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There is increasing evidence for specific cortical and subcortical large-scale human epileptic networks to be involved in the generation, spread, and termination of not only primary generalized but also focal onset seizures. The complex…

Neurons and Cognition · Quantitative Biology 2016-10-07 Christian Geier , Marie-Therese Kuhnert , Christian E. Elger , Klaus Lehnertz

Epilepsy is one of the most occurring neurological diseases. The main characteristic of this disease is a frequent seizure, which is an electrical imbalance in the brain. It is generally accompanied by shaking of body parts and even leads…

Machine Learning · Computer Science 2023-03-22 Shivam Gupta , Virender Ranga , Priyansh Agrawal

Epileptic seizures are generated in cerebral networks that propagate ictal and interictal activity. The structure of cerebral networks underpinning epileptic activity can be inferred from diffusion-weighted MRI (DWI). However, publicly…

Epileptic seizures are neurological disorders characterized by abnormal and excessive electrical activity in the brain, resulting in recurrent seizure events. Electroencephalogram (EEG) signals are widely used for seizure diagnosis due to…

Machine Learning · Computer Science 2026-04-02 Ferdaus Anam Jibon , Fazlul Hasan Siddiqui , F. Deeba , Gahangir Hossain

An ability to map seizure-generating brain tissue, i.e., the seizure onset zone (SOZ), without recording actual seizures could reduce the duration of invasive EEG monitoring for patients with drug-resistant epilepsy. A widely-adopted…

Predicting seizure freedom is essential for tailoring epilepsy treatment. But accurate prediction remains challenging with traditional methods, especially with diverse patient populations. This study developed a deep learning-based graph…

A brain wide association study (BWAS) based on the logistic regression was first developed and applied to a large population of epilepsy patients (168) and healthy controls (136). It was found that the most significant links associated with…

Medical Physics · Physics 2012-09-26 Wei Cheng , Xuejuan Zhang , Ge Tian , Jianfeng Feng , Zhengge Wang , Zhiqiang Zhang , GuangMing Lu

Electrocorticography (ECoG) provides direct measurements of synchronized postsynaptic potentials at the exposed cortical surface. Patterns of signal covariance across ECoG sensors have been associated with diverse cognitive functions and…

Neurons and Cognition · Quantitative Biology 2017-06-20 Richard F. Betzel , John D. Medaglia , Ari E. Kahn , Jonathan Soffer , Daniel R. Schonhaut , Danielle S. Bassett

The evidence indicates that intracranial EEG connectivity, as estimated from daily resting state recordings from epileptic patients, may be capable of identifying preictal states. In this study, we employed hyperbolic embedding of brain…

Neurons and Cognition · Quantitative Biology 2025-05-28 Martin Guillemaud , Louis Cousyn , Vincent Navarro , Mario Chavez

Epilepsy is a chronic neurological disorder affecting 1\% of people worldwide, deep learning (DL) algorithms-based electroencephalograph (EEG) analysis provides the possibility for accurate epileptic seizure (ES) prediction, thereby…

Signal Processing · Electrical Eng. & Systems 2022-05-10 Yankun Xu , Jie Yang , Mohamad Sawan

Epilepsy is a neurological disorder identified by sudden and recurrent seizures, which are believed to be accompanied by distinct changes in brain dynamics. Exploring the dynamic changes of brain network states during seizures can pave the…

Signal Processing · Electrical Eng. & Systems 2023-10-06 Atefeh Khoshkhahtinat , Hoda Mohammadzade

Epilepsy is the most common neurological disorder and an accurate forecast of seizures would help to overcome the patient's uncertainty and helplessness. In this contribution, we present and discuss a novel methodology for the…

Epilepsy affects more than 50 million people worldwide, making it one of the world's most prevalent neurological diseases. The main symptom of epilepsy is seizures, which occur abruptly and can cause serious injury or death. The ability to…

Signal Processing · Electrical Eng. & Systems 2024-02-06 Zakary Georgis-Yap , Milos R. Popovic , Shehroz S. Khan

In this paper, we introduce SeizNet, a closed-loop system for predicting epileptic seizures through the use of Deep Learning (DL) method and implantable sensor networks. While pharmacological treatment is effective for some epilepsy…

Introduction: Approximately 23 million or 30% of epilepsy patients worldwide suffer from drug-resistant epilepsy (DRE). The unpredictability of seizure occurrences, which causes safety issues as well as social concerns, restrict the…

Machine Learning · Computer Science 2024-10-10 Shriya Jaddu , Sidh Jaddu , Camilo Gutierrez , Quincy K. Tran

Magnetic resonance imaging (MRI) is a crucial tool to identify brain abnormalities in a wide range of neurological disorders. In focal epilepsy MRI is used to identify structural cerebral abnormalities. For covert lesions, machine learning…

Epilepsy is a disorder of the brain denoted by frequent seizures. The symptoms of seizure include confusion, abnormal staring, and rapid, sudden, and uncontrollable hand movements. Epileptic seizure detection methods involve neurological…

Complex spatial connectivity patterns, such as interictal suppression and ictal propagation, complicate accurate drug-resistant epilepsy (DRE) seizure detection using stereotactic electroencephalography (SEEG) and traditional machine…

Signal Processing · Electrical Eng. & Systems 2025-12-03 Yiping Wang , Peiren Wang , Zhenye Li , Fang Liu , Jinguo Huang

Epilepsy surgery, particularly for temporal lobe epilepsy (TLE), remains a vital treatment option for patients with drug-resistant seizures. However, accurately predicting surgical outcomes remains a significant challenge. This study…

Neurons and Cognition · Quantitative Biology 2025-07-22 Martin Guillemaud , Alice Longhena , Louis Cousyn , Valerio Frazzini , Bertrand Mathon , Vincent Navarro , Mario Chavez

Epilepsy is a disease in which frequent seizures occur due to abnormal activity of neurons. Patients affected by this disease can be treated with the help of medicines or surgical procedures. However, both of these methods are not quite…

Neurons and Cognition · Quantitative Biology 2020-04-20 Syed Muhammad Usman , Shahzad Latif , Arshad Beg