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We assess electrical brain dynamics before, during, and after one-hundred human epileptic seizures with different anatomical onset locations by statistical and spectral properties of functionally defined networks. We observe a concave-like…

Neurons and Cognition · Quantitative Biology 2013-11-25 Kaspar A. Schindler , Stephan Bialonski , Marie-Therese Horstmann , Christian E. Elger , Klaus Lehnertz

Intracranial EEG (IEEG) is used for 2 main purposes, to determine: (1) if epileptic networks are amenable to focal treatment and (2) where to intervene. Currently these questions are answered qualitatively and sometimes differently across…

Epilepsy is known to drastically alter brain dynamics during seizures (ictal periods), but its effects on background (non-ictal) brain dynamics remain poorly understood. To investigate this, we analyzed an in-house dataset of brain activity…

The identification of abnormal electrographic activity is important in a wide range of neurological disorders, including epilepsy for localising epileptogenic tissue. However, this identification may be challenging during non-seizure…

Epilepsy is a chronic neurological disorder affecting more than 50 million people globally. An epileptic seizure acts like a temporary shock to the neuronal system, disrupting normal electrical activity in the brain. Epilepsy is frequently…

Neurons and Cognition · Quantitative Biology 2021-01-26 Matheus B. Guerrero , Raphaël Huser , Hernando Ombao

Epilepsy is a chronic neurological disorder affecting more than 65 million people worldwide and manifested by recurrent unprovoked seizures. The unpredictability of seizures not only degrades the quality of life of the patients, but it can…

Signal Processing · Electrical Eng. & Systems 2019-11-13 Damian Pascual , Amir Aminifar , David Atienza , Philippe Ryvlin , Roger Wattenhofer

Targeted electrical stimulation of the brain perturbs neural networks and modulates their rhythmic activity both at the site of stimulation and at remote brain regions. Understanding, or even predicting, this neuromodulatory effect is…

Neurons and Cognition · Quantitative Biology 2021-06-29 Christoforos Papasavvas , Peter Neal Taylor , Yujiang Wang

Accurate prediction of epileptic seizures has remained elusive, despite the many advances in machine learning and time-series classification. In this work, we develop a convolutional network module that exploits Electroencephalogram (EEG)…

Image and Video Processing · Electrical Eng. & Systems 2020-07-24 Ramy Hussein , Soojin Lee , Rabab Ward , Martin J. McKeown

Epilepsy is a dynamic and complex neurological disease affecting about 1% of the worldwide population, among which 30% of the patients are drug-resistant. Epilepsy is characterized by recurrent episodes of paroxysmal neural discharges (the…

Neurons and Cognition · Quantitative Biology 2021-01-27 Elif Köksal Ersöz , Julien Modolo , Fabrice Bartolomei , Fabrice Wendling

Understanding the relationship between the dynamics of neural processes and the anatomical substrate of the brain is a central question in neuroscience. On the one hand, modern neuroimaging technologies, such as diffusion tensor imaging,…

In many realistic networks, the edges representing the interactions between the nodes are time-varying. There is growing evidence that the complex network that models the dynamics of the human brain has time-varying interconnections, i.e.,…

Neurons and Cognition · Quantitative Biology 2016-11-29 G Manjunath

Objective: This work investigates the hypothesis that focal seizures can be predicted using scalp electroencephalogram (EEG) data. Our first aim is to learn features that distinguish between the interictal and preictal regions. The second…

Machine Learning · Computer Science 2018-05-30 Haidar Khan , Lara Marcuse , Madeline Fields , Kalina Swann , Bülent Yener

Epilepsy which is characterized by seizures is studied using EEG signals by recording the electrical activity of the brain. Different types of communication between different parts of the brain are characterized by many state of the art…

Machine Learning · Computer Science 2020-09-29 Mohammad Mansour , Fouad Khnaisser , Hmayag Partamian

Early warning for epilepsy patients is crucial for their safety and well-being, in particular to prevent or minimize the severity of seizures. Through the patients' EEG data, we propose a meta learning framework to improve the prediction of…

Machine Learning · Computer Science 2024-01-12 Peng Zhang , Ting Gao , Jin Guo , Jinqiao Duan , Sergey Nikolenko

The distributed nature of the neural substrate, and the difficulty of establishing necessity from correlative data, combine to render the mapping of brain function a far harder task than it seems. Methods capable of combining connective…

Epileptic seizures are characterised by abnormal brain dynamics at multiple scales, engaging single neurons, neuronal ensembles and coarse brain regions. Key to understanding the cause of such emergent population dynamics, is capturing the…

Neurons and Cognition · Quantitative Biology 2022-12-13 Dominic RW Burrows

Multi-channel EEG signals are commonly used for the diagnosis and assessment of diseases such as epilepsy. Currently, various EEG diagnostic algorithms based on deep learning have been developed. However, most research efforts focus solely…

Signal Processing · Electrical Eng. & Systems 2024-10-24 Zekun Jiang , Wei Dai , Qu Wei , Ziyuan Qin , Kang Li , Le Zhang

Epileptic seizures are characterized by abnormal and excessive neural activity, where cortical network dynamics seem to become unstable. However, most of the time, during seizure-free periods, cortex of epilepsy patients shows perfectly…

Neurons and Cognition · Quantitative Biology 2021-04-06 Annika Hagemann , Jens Wilting , Bita Samimizad , Florian Mormann , Viola Priesemann

We investigate assortativity of functional brain networks before, during, and after one-hundred epileptic seizures with different anatomical onset locations. We construct binary functional networks from multi-channel electroencephalographic…

Data Analysis, Statistics and Probability · Physics 2013-09-24 Stephan Bialonski , Klaus Lehnertz

Epilepsy is one of the most common neurological disorders globally, affecting millions of individuals. Despite significant advancements, the precise mechanisms underlying this condition remain largely unknown, making accurately predicting…

Systems and Control · Electrical Eng. & Systems 2024-04-05 Yuzhen Qin , Ahmed El-Gazzar , Danielle S. Bassett , Fabio Pasqualetti , Marcel van Gerven