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Efficient early diagnosis is paramount in addressing the complexities of Parkinson's disease because timely intervention can substantially mitigate symptom progression and improve patient outcomes. In this paper, we present a pioneering…

Signal Processing · Electrical Eng. & Systems 2024-04-25 Alireza Rashnu , Armin Salimi-Badr

Identification of risk factors associated with falls in people with Parkinson's Disease (PD) is important due to their high risk of falling. In this study, various ways of utilizing the Unified Parkinson's Disease Rating Scale (UPDRS) were…

Applications · Statistics 2019-10-04 Sarini Abdullah , Nicole White , James McGree , Kerrie Mengersen , Graham Kerr

Severity assessment of Parkinson's disease (PD) using wearable sensors offers an effective, objective basis for clinical management. However, general-purpose time series models often lack pathological specificity in feature extraction,…

Machine Learning · Computer Science 2025-10-14 Weiming Zhao , Xulong Wang , Jun Qi , Yun Yang , Po Yang

The rapid advancement of medical technology has led to an exponential increase in multi-modal medical data, including imaging, genomics, and electronic health records (EHRs). Graph neural networks (GNNs) have been widely used to represent…

Quantitative Methods · Quantitative Biology 2024-10-03 Favour Nerrise , Alice Louise Heiman , Ehsan Adeli

In many clinical trials studying neurodegenerative diseases such as Parkinson's disease (PD), multiple longitudinal outcomes are collected to fully explore the multidimensional impairment caused by this disease. If the outcomes deteriorate…

Applications · Statistics 2017-05-18 Jue Wang , Sheng Luo , Liang Li

We seek to identify genes involved in Parkinson's Disease (PD) by combining information across different experiment types. Each experiment, taken individually, may contain too little information to distinguish some important genes from…

During the preceding decades, human gait analysis has been the center of attention for the scientific community, while the association between gait analysis and overall health monitoring has been extensively reported. Technological advances…

In recent years, applications of data mining methods are become more popular in many fields of medical diagnosis and evaluations. The data mining methods are appropriate tools for discovering and extracting of available knowledge in medical…

Computational Engineering, Finance, and Science · Computer Science 2013-12-10 Peyman Mohammadi , Abdolreza Hatamlou , Mohammad Masdari

Multivariate regression models for age estimation are a powerful tool for assessing abnormal brain morphology associated to neuropathology. Age prediction models are built on cohorts of healthy subjects and are built to reflect normal aging…

Computer Vision and Pattern Recognition · Computer Science 2018-04-05 Benjamin Gutierrez Becker , Tassilo Klein , Christian Wachinger

There is a growing interest in using pose estimation algorithms for video-based assessment of Bradykinesia in Parkinson's Disease (PD) to facilitate remote disease assessment and monitoring. However, the accuracy of pose estimation…

Computer Vision and Pattern Recognition · Computer Science 2023-08-29 Gabriela T. Acevedo Trebbau , Andrea Bandini , Diego L. Guarin

Differential diagnosis among parkinsonian syndromes remains a clinical challenge due to overlapping motor symptoms and subtle gait abnormalities. Accurate differentiation is crucial for treatment planning and prognosis. While gait analysis…

Machine Learning · Computer Science 2026-03-09 Jhonathan Barrios , Wolfram Erlhagen , Miguel F. Gago , Estela Bicho , Flora Ferreira

We present a computational model that highlights the role of basal ganglia (BG) in generating simple reaching movements. The model is cast within the reinforcement learning (RL) framework with the correspondence between RL components and…

Neurons and Cognition · Quantitative Biology 2011-01-26 K. N. Magdoom , D. Subramanian , V. S. Chakravarthy , B. Ravindran , Shun-ichi Amari , N. Meenakshisundaram

In this paper, we leverage gait to potentially detect some of the important neurological disorders, namely Parkinson's disease, Diplegia, Hemiplegia, and Huntington's Chorea. Persons with these neurological disorders often have a very…

Computer Vision and Pattern Recognition · Computer Science 2020-08-18 Daksh Goyal , Koteswar Rao Jerripothula , Ankush Mittal

This paper presents an efficient deep neural network model for diagnosing Parkinson's disease from gait. More specifically, we introduce a hybrid ConvNet-Transformer architecture to accurately diagnose the disease by detecting the severity…

Computer Vision and Pattern Recognition · Computer Science 2023-11-07 Safwen Naimi , Wassim Bouachir , Guillaume-Alexandre Bilodeau

Freezing of gait is a Parkinson's Disease symptom that episodically inflicts a patient with the inability to step or turn while walking. While medical experts have discovered various triggers and alleviating actions for freezing of gait,…

Machine Learning · Computer Science 2023-10-11 Wen Tao Mo , Jonathan H. Chan

In this paper, an explainable deep learning-based classifier based on adaptive sinc filters for Parkinson's Disease diagnosis (PD) along with determining its severity, based on analyzing the gait cycle (SincPD) is presented. Considering the…

Signal Processing · Electrical Eng. & Systems 2025-02-26 Armin Salimi-Badr , Mahan Veisi , Sadra Berangi

Electroencephalography has been established as an effective method for detecting Parkinson's disease, typically diagnosed early.Current Parkinson's disease detection methods have shown significant success within individual datasets,…

Machine Learning · Computer Science 2025-08-21 Qian Zhang , Ruilin Zhang , Biaokai Zhu , Xun Han , Jun Xiao , Yifan Liu , Zhe Wang

A widely used test for the diagnosis of Parkinson's disease (PD) and Essential tremor (ET) is hand-drawn shapes,where the analysis is observationally performed by the examining neurologist. This method is subjective and is prone to bias…

Computer Vision and Pattern Recognition · Computer Science 2020-06-23 Nabeel Seedat , Vered Aharonson , Ilana Schlesinger

Sensors from smart consumer devices have demonstrated high potential to serve as digital biomarkers in the identification of movement disorders in recent years. With the usage of broadly available smartwatches we have recorded participants…

Machine Learning · Computer Science 2022-05-12 Alexander Brenner , Michael Fujarski , Tobias Warnecke , Julian Varghese

Parkinson's Disease (PD) is a neurodegenerative disorder characterized by motor symptoms, including altered voice production in the early stages. Early diagnosis is crucial not only to improve PD patients' quality of life but also to…

Audio and Speech Processing · Electrical Eng. & Systems 2025-01-15 Maksim Siniukov , Ellie Xing , Sanaz Attaripour Isfahani , Mohammad Soleymani