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Atypical Parkinsonian Disorders (APD), also known as Parkinson-plus syndrome, are a group of neurodegenerative diseases that include progressive supranuclear palsy (PSP) and multiple system atrophy (MSA). In the early stages, overlapping…
Parkinson's Disease (PD) is a chronic and progressive neurological disorder that results in rigidity, tremors and postural instability. There is no definite medical test to diagnose PD and diagnosis is mostly a clinical exercise. Although…
Parkinson's Disease(PD) is one of the major nervous system disorders that affect people over 60. PD can cause cognitive impairments. In this work, we explore various approaches to identify Parkinson's using Magnetic Resonance (MR) T1 images…
Parkinson's disease (PD), a severe and progressive neurological illness, affects millions of individuals worldwide. For effective treatment and management of PD, an accurate and early diagnosis is crucial. This study presents a deep…
Parkinson's disease is a widespread neurodegenerative condition necessitating early diagnosis for effective intervention. This paper introduces an innovative method for diagnosing Parkinson's disease through the analysis of human EEG…
Parkinson's disease (PD) is a common neurodegenerative disorder that severely diminishes patients' quality of life. Its global prevalence has increased markedly in recent decades. Current diagnostic workflows are complex and heavily reliant…
We present a web-based framework to screen for Parkinson's disease (PD) by allowing users to perform neurological tests in their homes. Our web framework guides the users to complete three tasks involving speech, facial expression, and…
Parkinson's disease (PD) poses challenges in diagnosis and monitoring due to its progressive nature and complex symptoms. This study introduces a novel approach utilizing surface electromyography (sEMG) to objectively assess PD severity,…
Parkinson's Disease (PD) is one of the most prevalent neurodegenerative diseases that affects tens of millions of Americans. PD is highly progressive and heterogeneous. Quite a few studies have been conducted in recent years on predictive…
One of the symptoms of Parkinson's disease (PD) is hypomimia or reduced facial expressions. In this paper, we present a digital biomarker for PD that utilizes the study of micro-expressions. We analyzed the facial action units (AU) from…
Parkinson's disease (PD) is a neurodegenerative disorder, manifesting with motor and non-motor symptoms. Depressive symptoms are prevalent in PD, affecting up to 45% of patients. They are often underdiagnosed due to overlapping motor…
Accurate and interpretable gait analysis plays a crucial role in the early detection of Parkinsons disease (PD),yet most existing approaches remain limited by single-modality inputs, low robustness, and a lack of clinical transparency. This…
Objective: We present the PaHaW Parkinson's disease handwriting database, consisting of handwriting samples from Parkinson's disease (PD) patients and healthy controls. Our goal is to show that kinematic features and pressure features in…
Parkinson's disease (PD) is a chronic neurodegenerative disease. Early diagnosis is essential to mitigate the progressive deterioration of patients' quality of life. The most characteristic motor symptoms are very mild in the early stages,…
Parkinson's disease (PD) is a common neurodegenerative disorder with a poorly understood physiopathology and no established biomarkers for the diagnosis of early stages and for prediction of disease progression. Several neuroimaging…
Speech impairments in Parkinson's disease (PD) provide significant early indicators for diagnosis. While models for speech-based PD detection have shown strong performance, their interpretability remains underexplored. This study…
Robot-led physical therapy (PT) offers a promising avenue to enhance the care provided by clinical exercise specialists (ES) and physical and occupational therapists to improve patients' adherence to prescribed exercises outside of a…
Parkinsons disease is the second most prevalent neurodegenerative disorder with over ten million active cases worldwide and one million new diagnoses per year. Detecting and subsequently diagnosing the disease is challenging because of…
Parkinson's disease is a neurodegenerative disorder characterized by the presence of different motor impairments. Information from speech, handwriting, and gait signals have been considered to evaluate the neurological state of the…
Case vs control comparisons have been the classical approach to the study of neurological diseases. However, most patients will not fall cleanly into either group. Instead, clinicians will typically find patients that cannot be classified…