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Parkinson's Disease (PD) medication management presents unique challenges due to heterogeneous disease progression and treatment response. Neurologists must balance symptom control with optimal dopaminergic dosing based on functional…

Machine Learning · Computer Science 2025-08-15 Ricardo Diaz-Rincon , Muxuan Liang , Adolfo Ramirez-Zamora , Benjamin Shickel

Orofacial deficits are common in people with Parkinson's disease (PD) and their evolution might represent an important biomarker of disease progression. We are developing an automated system for assessment of orofacial function in PD that…

Computer Vision and Pattern Recognition · Computer Science 2020-03-19 Diego L. Guarin , Aidan Dempster , Andrea Bandini , Yana Yunusova , Babak Taati

Objective gait assessment in Parkinson's Disease (PD) is limited by the absence of large, diverse, and clinically annotated motion datasets. We introduce CARE-PD, the largest publicly available archive of 3D mesh gait data for PD, and the…

This paper presents a novel deep learning enabled, video based analysis framework for assessing the Unified Parkinsons Disease Rating Scale (UPDRS) that can be used in the clinic or at home. We report results from comparing the performance…

Computer Vision and Pattern Recognition · Computer Science 2021-04-13 Deval Mehta , Umar Asif , Tian Hao , Erhan Bilal , Stefan Von Cavallar , Stefan Harrer , Jeffrey Rogers

Parkinson's disease (PD) is a non-curable disease that commonly found among elders that greatly reduce their quality of life. PD primarily affects the gait pattern and slowly changes the walking gait from the normality to disability. The…

Machine Learning · Computer Science 2021-02-02 Musthaq Ahamed , P. D. S. H. Gunawardane , Nimali T. Medagedara

Parkinson's disease (PD) is a prevalent neurodegenerative disorder known for its impact on motor neurons, causing symptoms like tremors, stiffness, and gait difficulties. This study explores the potential of vocal feature alterations in PD…

Parkinson's Disease (PD) affects millions globally, impacting movement. Prior research utilized deep learning for PD prediction, primarily focusing on medical images, neglecting the data's underlying manifold structure. This work proposes a…

Computer Vision and Pattern Recognition · Computer Science 2024-08-27 Jun-En Ding , Chien-Chin Hsu , Feng Liu

Parkinson's disease (PD) is a common neurodegenerative disorder with a prevalence rate estimated to 2.0% for people aged over 65 years. Cardinal motor symptoms of PD such as rigidity and bradykinesia affect the muscles involved in the…

Systems and Control · Electrical Eng. & Systems 2023-01-23 Jan Mucha , Zoltan Galaz , Jiri Mekyska , Marcos Faundez-Zanuy , Vojtech Zvoncak , Zdenek Smekal , Lubos Brabenec , Irena Rektorova

Parkinson's Disease (PD) is a neurodegenerative disorder that significantly impacts motor and non-motor functions. There is currently no treatment that slows or stops neurodegeneration in PD. In this context, assistive technologies (ATs)…

Human-Computer Interaction · Computer Science 2025-05-27 Subek Acharya , Sansrit Paudel

Accurate diagnosis of Parkinson disease, especially in its early stages, can be a challenging task. The application of machine learning techniques helps improve the diagnostic accuracy of Parkinson disease detection but only few studies…

Machine Learning · Computer Science 2024-12-25 Majid Ali , Hina Shakir , Asia Samreen , Sohaib Ahmed

Parkinson's disease (PD) is a degenerative and progressive neurological condition. Early diagnosis can improve treatment for patients and is performed through dopaminergic imaging techniques like the SPECT DaTscan. In this study, we propose…

Computer Vision and Pattern Recognition · Computer Science 2020-08-04 Pavan Rajkumar Magesh , Richard Delwin Myloth , Rijo Jackson Tom

Background and Objective: Parkinson's disease (PD) is the second most common progressive neurological condition after Alzheimer's, characterized by motor and non-motor symptoms. Developing a method to diagnose the condition in its beginning…

Machine Learning · Computer Science 2022-10-05 Paria Ghaheri , Hamid Nasiri , Ahmadreza Shateri , Arman Homafar

Quantitative estimation of human joint motion in daily living spaces is essential for early detection and rehabilitation tracking of neuromusculoskeletal disorders (e.g., Parkinson's) and mitigating trip and fall risks for older adults.…

Human-Computer Interaction · Computer Science 2025-03-24 Yiwen Dong , Jessica Rose , Hae Young Noh

Sit-to-stand transitions are an important part of activities of daily living and play a key role in functional mobility in humans. The sit-to-stand movement is often affected in older adults due to frailty and in patients with motor…

Falls are detrimental to people with Parkinson's Disease (PD) because of the potentially severe consequences to the patients' quality of life. While many studies have attempted to predict falls/non-falls, this study aimed to determine…

Applications · Statistics 2019-10-07 Sarini Abdullah , James McGree , Nicole White , Kerrie Mengersen , Graham Kerr

Parkinson's disease (PD) is a chronic, degenerative neurological disorder. PD cannot be prevented, slowed or cured as of today but highly effective symptomatic treatments are available. We consider relevant estimands and treatment effect…

Parkinson's disease is a common neurological disease, entailing a multitude of motor deficiency symptoms. In this project, we developed a device with an uploaded edge machine learning algorithm that can detect the onset of freezing of gait…

Signal Processing · Electrical Eng. & Systems 2022-11-15 Purnoor Ghuman , Tyama Lyall , Usama Mahboob , Alia Aamir , Xilin Liu

This paper deals with a complex acoustic analysis of phonation in patients with Parkinson's disease (PD) with a special focus on estimation of disease progress that is described by 7 different clinical scales ,e. g. Unified Parkinson's…

Freezing-of-gait a mysterious symptom of Parkinsons disease and defined as a sudden loss of ability to move forward. Common treatments of freezing episodes are currently of moderate efficacy and can likely be improved through a reliable…

Signal Processing · Electrical Eng. & Systems 2020-09-29 Ying Wang , Floris Beuving , Jorik Nonnekes , Mike X Cohen , Xi Long , Ronald M Aarts , Richard Van Wezel

Objective: To apply deep learning pose estimation algorithms for vision-based assessment of parkinsonism and levodopa-induced dyskinesia (LID). Methods: Nine participants with Parkinson's disease (PD) and LID completed a levodopa infusion…

Computer Vision and Pattern Recognition · Computer Science 2018-11-12 Michael H. Li , Tiago A. Mestre , Susan H. Fox , Babak Taati
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