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We study instrumental-variable designs where policy reforms strongly shift the distribution of an endogenous variable but only weakly move its mean. We formalize this by introducing distributional relevance: instruments may be purely…

Econometrics · Economics 2026-02-12 Rowan Cherodian , Guy Tchuente

Mendelian randomization (MR) has become a popular approach to study the effect of a modifiable exposure on an outcome by using genetic variants as instrumental variables. A challenge in MR is that each genetic variant explains a relatively…

Methodology · Statistics 2020-10-13 Ting Ye , Jun Shao , Hyunseung Kang

Under treatment effect heterogeneity, an instrument identifies the instrument-specific local average treatment effect (LATE). With multiple instruments, two-stage least squares (2SLS) estimand is a weighted average of different LATEs. What…

Econometrics · Economics 2026-02-03 Seojeong Lee

In this paper, we propose a Bayesian channel estimator for intelligent reflecting surface-aided (IRS-aided) millimeter wave (mmWave) massive multiple-input multiple-output (MIMO) systems with semi-passive elements that can receive the…

Information Theory · Computer Science 2023-12-29 In-soo Kim , Mehdi Bennis , Jaeky Oh , Jaehoon Chung , Junil Choi

This paper studies the identification and estimation of the optimal linear approximation of a structural regression function. The parameter in the linear approximation is called the Optimal Linear Instrumental Variables Approximation…

Econometrics · Economics 2020-02-06 Juan Carlos Escanciano , Wei Li

We consider estimation and inference in a linear model with endogenous regressors where the parameters of interest change across two samples. If the first-stage is common, we show how to use this information to obtain more efficient…

Econometrics · Economics 2024-06-26 Bertille Antoine , Otilia Boldea , Niccolo Zaccaria

In a linear instrumental variables (IV) setting for estimating the causal effects of multiple confounded exposure/treatment variables on an outcome, we investigate the adaptive Lasso method for selecting valid instrumental variables from a…

Methodology · Statistics 2022-08-11 Xiaoran Liang , Eleanor Sanderson , Frank Windmeijer

Instrumental variable (IV) regression is a strategy for learning causal relationships in observational data. If measurements of input X and output Y are confounded, the causal relationship can nonetheless be identified if an instrumental…

Machine Learning · Computer Science 2020-07-17 Rahul Singh , Maneesh Sahani , Arthur Gretton

We discuss the fundamental issue of identification in linear instrumental variable (IV) models with unknown IV validity. With the assumption of the "sparsest rule", which is equivalent to the plurality rule but becomes operational in…

Methodology · Statistics 2023-12-06 Yiqi Lin , Frank Windmeijer , Xinyuan Song , Qingliang Fan

Mendelian randomization uses genetic variants as instrumental variables to make causal inferences about the effects of modifiable risk factors on diseases from observational data. One of the major challenges in Mendelian randomization is…

Methodology · Statistics 2024-10-29 Youpeng Su , Siqi Xu , Yilei Ma , Ping Yin , Wing Kam Fung , Hongwei Jiang , Peng Wang

Many applications in mechanical, acoustic, and electronic engineering require estimating complex dynamical models, often represented as additive multi-input multi-output (MIMO) transfer functions with structural constraints. This paper…

Systems and Control · Electrical Eng. & Systems 2025-05-21 Rodrigo A. González , Maarten van der Hulst , Koen Classens , Tom Oomen

Recent advances in the literature have demonstrated that standard supervised learning algorithms are ill-suited for problems with endogenous explanatory variables. To correct for the endogeneity bias, many variants of nonparameteric…

Econometrics · Economics 2021-01-18 Edvard Bakhitov , Amandeep Singh

This paper is concerned with inference about low-dimensional components of a high-dimensional parameter vector $\beta^0$ which is identified through instrumental variables. We allow for eigenvalues of the expected outer product of included…

Econometrics · Economics 2020-08-05 Christoph Breunig , Enno Mammen , Anna Simoni

Methodological development of the Model-implied Instrumental Variable (MIIV) estimation framework has proved fruitful over the last three decades. Major milestones include Bollen's (1996) original development of the MIIV estimator and its…

Methodology · Statistics 2025-01-08 Zachary F. Fisher , Kenneth A. Bollen

Instrumental variable (IV) strategies are widely used in political science to establish causal relationships. However, the identifying assumptions required by an IV design are demanding, and it remains challenging for researchers to assess…

Econometrics · Economics 2023-11-08 Apoorva Lal , Mac Lockhart , Yiqing Xu , Ziwen Zu

Nonparametric Instrumental Variables (NPIV) analysis is based on a conditional moment restriction. We show that if this moment condition is even slightly misspecified, say because instruments are not quite valid, then NPIV estimates can be…

Econometrics · Economics 2022-12-13 Ben Deaner

This paper develops a new specification test for the instrument weakness when the number of instruments $K_n$ is large with a magnitude comparable to the sample size $n$. The test relies on the fact that the difference between the two-stage…

Econometrics · Economics 2023-03-01 Zhenhong Huang , Chen Wang , Jianfeng Yao

We establish the first global convergence result of neural networks for two stage least squares (2SLS) approach in nonparametric instrumental variable regression (NPIV). This is achieved by adopting a lifted perspective through mean-field…

Machine Learning · Statistics 2025-11-19 Zonghao Chen , Atsushi Nitanda , Arthur Gretton , Taiji Suzuki

Finding valid instruments is difficult. We propose Validity Set Instrumental Variable (VSIV) estimation, a method for estimating local average treatment effects (LATEs) in heterogeneous causal effect models when the instruments are…

Econometrics · Economics 2025-02-11 Zhenting Sun , Kaspar Wüthrich

As longitudinal data becomes more available in many settings, policy makers are increasingly interested in the effect of time-varying treatments (e.g. sustained treatment strategies). In settings such as this, the preferred analysis…

Methodology · Statistics 2024-07-11 Daniel Tompsett , Stijn Vansteelandt , Richard Grieve , Irene Petersen , Manuel Gomes