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Miniature fluorescence microscopes are a standard tool in systems biology. However, widefield miniature microscopes capture only 2D information, and modifications that enable 3D capabilities increase the size and weight and have poor…

Image and Video Processing · Electrical Eng. & Systems 2020-10-13 Kyrollos Yanny , Nick Antipa , William Liberti , Sam Dehaeck , Kristina Monakhova , Fanglin Linda Liu , Konlin Shen , Ren Ng , Laura Waller

Single fluorescent molecules, behaving as ideal electric dipole emitters, are powerful nanoscopic probes of complex optical fields. Here, this property is exploited to precisely map the polarization and vectorial structure of tightly…

I propose a superoscillation measurement method for subdiffraction incoherent optical sources, with potential applications in astronomy, remote sensing, fluorescence microscopy, and spectroscopy. The proposal, based on coherent optical…

Quantum Physics · Physics 2022-10-10 Mankei Tsang

Fabricating freeform mirrors relies on accurate optical figuring processes capable of arbitrarily modifying low-spatial frequency height without creating higher-spatial frequency errors. We present a scalable process to accurately figure…

Optics · Physics 2022-05-12 Brandon D. Chalifoux , Kevin A. Laverty , Ian J. Arnold

Absolute calibration of the Pierre Auger Observatory fluorescence detectors uses a light source at the telescope aperture. The technique accounts for the ombined effects of all detector components in a single measurement. The calibrated 2.5…

Astrophysics · Physics 2019-08-14 P. Bauleo , J. Brack , L. Garrard , J. Harton , R. Knapik , R. Meyhandan , A. C. Rovero , A. Tamashiro , D. Warner

Recently, imaging by microspheres and dielectric particle-lenses emerged as a simple solution to obtaining super-resolution images of nanoscale devices and structures. Calibrated resolution of ~{\lambda}/6 - {\lambda}/8 has been…

Optics · Physics 2021-08-26 Zengbo Wang , Boris Luk'yanchuk

Although cardiovascular diseases are the leading cause of death globally, non-invasive and inexpensive diagnostic tools for the identification of associated unstable atherosclerotic plaques are not yet available. Scanning acoustic…

With the advent of microsphere assisted microscopy in 2011, this technique emerged as a simple and easy way to obtain optical super-resolution. Although the possible mechanisms of imaging by microspheres are debated in the literature, most…

Optics · Physics 2015-08-27 Navid Farahi

Multiple lidars are prevalently used on mobile vehicles for rendering a broad view to enhance the performance of localization and perception systems. However, precise calibration of multiple lidars is challenging since the feature…

Computer Vision and Pattern Recognition · Computer Science 2019-04-30 Jianhao Jiao , Qinghai Liao , Yilong Zhu , Tianyu Liu , Yang Yu , Rui Fan , Lujia Wang , Ming Liu

Low-light optical imaging refers to the use of cameras to capture images with minimal photon flux. This area has broad application to diverse fields, including optical microscopy for biological studies. In such studies, it is important to…

A powerful fabrication strategy based on three-dimensional direct laser writing for the rapid prototyping of opto-mechanical components with critical features ranging from several hundred nm to a few mm is demonstrated here. As an example,…

Applied Physics · Physics 2020-01-10 Y. Li , S. Park , M. McLamb , M. Lata , D. Childers , T. Hofmann

Diffractive lenses have recently been applied to the domain of multispectral imaging in the X-ray and UV regimes where they can achieve very high resolution as compared to reflective and refractive optics. Conventionally, spectral…

Image and Video Processing · Electrical Eng. & Systems 2020-05-26 Evan Widloski , Ulas Kamaci , Farzad Kamalabadi

Nonlinear optical microscopy allows rapid high-resolution microscopy with image contrast generated from intrinsic properties of the sample. Established modalities such as multiphoton excited fluorescence and second/third-harmonic generation…

Colouration by surface nanostructuring has attracted a great deal of attention by the virtue of making use of environment-friendly recyclable materials and generating non-bleaching colours [1-8]. Recently, it was found possible to delegate…

A fast and practical method is described for calculating the microlensed flux variance of an arbitrary source by uncorrelated stars. The required inputs are the mean convergence and shear due to the smoothed potential of the lensing galaxy,…

Cosmology and Nongalactic Astrophysics · Physics 2015-06-17 Jeremy Goodman , Ai-Lei Sun

Colocalization is a powerful tool to study the interactions between fluorescently labeled molecules in biological fluorescence microscopy. However, existing techniques for colocalization analysis have not undergone continued development…

Methodology · Statistics 2018-02-14 Shulei Wang , Ellen T. Arena , Kevin W. Eliceiri , Ming Yuan

In this paper, we provide an overview of development of a structured light 3D-scanner based on combination of binary-coded patterns and sinusoidal phase-shifted fringe patterns called Coded Phase-shift technique. Further, we describe the…

Image and Video Processing · Electrical Eng. & Systems 2021-10-22 Pranav Kant Gaur , D. M. Sarode , S. K. Bose

Laser frequency combs (LFCs) are well on their way to becoming the next-generation calibration sources for precision astronomical spectroscopy. This development is considered key in the hunt for low-mass rocky exoplanets around solar-type…

An integrated microscope that combines different optical techniques for simultaneous imaging is demonstrated. The microscope enables spectral-domain optical coherence microscopy based on optical backscatter, and multi-photon microscopy for…

Optics · Physics 2009-11-11 C. Vinegoni , T. Ralston , W. Tan , W. Luo , D. L. Marks , S. A. Boppart

We have demonstrated several inexpensive methods which can be used to measure the deflection angles of prisms with microradian precision. The methods are self-referenced, using various reversals to achieve absolute measurements without the…

Optics · Physics 2009-11-11 Rebecca Olson , Justin Paul , Scott Bergeson , Dallin S. Durfee
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