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The first step to understanding brain function is to determine the brain's network structure. We report a three-dimensional analysis of the brain network of the fruit fly Drosophila melanogaster by synchrotron-radiation tomographic…

Neurons and Cognition · Quantitative Biology 2016-09-09 Ryuta Mizutani , Rino Saiga , Akihisa Takeuchi , Kentaro Uesugi , Yoshio Suzuki

One of the crucial questions in neuroscience is how a rich functional repertoire of brain states relates to its underlying structural organization. How to study the associations between these structural and functional layers is an open…

Neurons and Cognition · Quantitative Biology 2018-02-22 Enrico Amico , Joaquín Goñi

Volumetric brain reconstructions provide an unprecedented opportunity to gain insights into the complex connectivity patterns of neurons in an increasing number of organisms. Here, we model and quantify the complexity of the resulting…

Neurons and Cognition · Quantitative Biology 2024-05-13 Anastasiya Salova , István A. Kovács

We demonstrate the first-ever nontrivial, biologically realistic connectome simulated on neuromorphic computing hardware. Specifically, we implement the whole-brain connectome of the adult Drosophila melanogaster (fruit fly) from the…

Distributed, Parallel, and Cluster Computing · Computer Science 2025-08-26 Felix Wang , Bradley H. Theilman , Fred Rothganger , William Severa , Craig M. Vineyard , James B. Aimone

Human brain is a layered structure, and performs not only a feedforward process from a lower layer to an upper layer but also a feedback process from an upper layer to a lower layer. The layer is a collection of neurons, and neural network…

Computer Vision and Pattern Recognition · Computer Science 2020-05-01 Eisuke Shibuya , Kazuhiro Hotta

Deep convolutional neural networks (CNNs) have demonstrated impressive performance on many visual tasks. Recently, they became useful models for the visual system in neuroscience. However, it is still not clear what are learned by CNNs in…

Neurons and Cognition · Quantitative Biology 2020-02-19 Qi Yan , Yajing Zheng , Shanshan Jia , Yichen Zhang , Zhaofei Yu , Feng Chen , Yonghong Tian , Tiejun Huang , Jian K. Liu

Decoding the heterogeneity of biological neural systems is key to understanding the nervous system's complex dynamical behaviors. This study analyzes the comprehensive Drosophila brain connectome, which is the most recent data set,…

Neurons and Cognition · Quantitative Biology 2025-10-01 Xiaoyu Zhang , Pengcheng Yang , Yifei Zhang , Bowei Qin , Qiang Luo , Wei Lin , Xin Lu

Grand efforts in neuroscience are working toward mapping the connectomes of many new species, including the near completion of the Drosophila melanogaster. It is important to ask whether these models could benefit artificial intelligence.…

Neural and Evolutionary Computing · Computer Science 2022-12-26 Samuel Schmidgall , Catherine Schuman , Maryam Parsa

Machine learning techniques have become increasingly popular in the field of resting state fMRI (functional magnetic resonance imaging) network based classification. However, the application of convolutional networks has been proposed only…

Machine Learning · Statistics 2017-07-24 Regina Meszlényi , Krisztian Buza , Zoltán Vidnyánszky

The current neuron reconstruction pipeline for electron microscopy (EM) data usually includes automatic image segmentation followed by extensive human expert proofreading. In this work, we aim to reduce human workload by predicting…

Computer Vision and Pattern Recognition · Computer Science 2024-01-09 Qihua Chen , Xuejin Chen , Chenxuan Wang , Yixiong Liu , Zhiwei Xiong , Feng Wu

We investigate how a residual network can learn to predict the dynamics of interacting shapes purely as an image-to-image regression task. With a simple 2d physics simulator, we generate short sequences composed of rectangles put in motion…

Computer Vision and Pattern Recognition · Computer Science 2016-11-28 François Fleuret

Rectilinear crawling locomotion is a primitive and common mode of locomotion in slender, soft-bodied animals. It requires coordinated contractions that propagate along a body that interacts frictionally with its environment. We propose a…

Biological Physics · Physics 2021-08-31 Shruti Mishra , Wim M. van Rees , L. Mahadevan

Functional MRI (fMRI) and diffusion MRI (dMRI) are non-invasive imaging modalities that allow in-vivo analysis of a patient's brain network (known as a connectome). Use of these technologies has enabled faster and better diagnoses and…

Machine Learning · Computer Science 2016-12-06 Colin J Brown , Ghassan Hamarneh

In this work, we propose a learning framework for identifying synapses using a deep and wide multi-scale recursive (DAWMR) network, previously considered in image segmentation applications. We apply this approach on electron microscopy data…

Computer Vision and Pattern Recognition · Computer Science 2014-09-08 Gary B. Huang , Stephen Plaza

Understanding how the visual cortex of the human brain really works is still an open problem for science today. A better understanding of natural intelligence could also benefit object-recognition algorithms based on convolutional neural…

Computer Vision and Pattern Recognition · Computer Science 2019-06-28 Anne-Ruth José Meijer , Arnoud Visser

Realtime model learning proves challenging for complex dynamical systems, such as drones flying in variable wind conditions. Machine learning technique such as deep neural networks have high representation power but is often too slow to…

Robotics · Computer Science 2022-05-26 Michael O'Connell , Guanya Shi , Xichen Shi , Soon-Jo Chung

Detecting small moving objects in complex backgrounds from an overhead perspective is a highly challenging task for machine vision systems. As an inspiration from nature, the avian visual system is capable of processing motion information…

Computer Vision and Pattern Recognition · Computer Science 2024-04-02 Pignge Hu , Xiaoteng Zhang , Mengmeng Li , Yingjie Zhu , Li Shi

We tackle classification based on brain connectivity derived from diffusion magnetic resonance images. We propose a machine-learning model inspired by graph convolutional networks (GCNs), which takes a brain connectivity input graph and…

Neurons and Cognition · Quantitative Biology 2023-09-21 Anees Kazi , Jocelyn Mora , Bruce Fischl , Adrian V. Dalca , Iman Aganj

Motion perception is a critical capability determining a variety of aspects of insects' life, including avoiding predators, foraging and so forth. A good number of motion detectors have been identified in the insects' visual pathways.…

Computer Vision and Pattern Recognition · Computer Science 2019-04-04 Qinbing Fu , Hongxin Wang , Cheng Hu , Shigang Yue

We aimed to explore the capability of deep learning to approximate the function instantiated by biological neural circuits-the functional connectome. Using deep neural networks, we performed supervised learning with firing rate observations…

Neurons and Cognition · Quantitative Biology 2022-11-24 Sihao Liu , Augustine N Mavor-Parker , Caswell Barry