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The brain's intricate connectome, a blueprint for its function, presents immense complexity, yet it arises from a compact genetic code, hinting at underlying low-dimensional organizational principles. This work bridges connectomics and…

Artificial Intelligence · Computer Science 2025-05-28 Yubin Li , Xingyu Liu , Guozhang Chen

Decoding the direction of translating objects in front of cluttered moving backgrounds, accurately and efficiently, is still a challenging problem. In nature, lightweight and low-powered flying insects apply motion vision to detect a moving…

Neurons and Cognition · Quantitative Biology 2020-07-03 Qinbing Fu , Shigang Yue

The dynamical evolution of complex networks underpins the structure-function relationships in natural and artificial systems. Yet, restoring a network's formation from a single static snapshot remains challenging. Here, we present a…

Physics and Society · Physics 2025-12-10 Jiu Zhang , Zhanwei Du , Hongwei Hu , Ke Wu , Tongchao Li , Chuan Shi , Xiaohui Huang , Yamir Moreno , Yanqing Hu

With respect to biological findings underlying fly's physiology in the past decade, we present a directionally selective neural network, with a feed-forward structure and entirely low-level visual processing, so as to implement direction…

Neural and Evolutionary Computing · Computer Science 2018-08-24 Qinbing Fu , Nicola Bellotto , Shigang Yue

Mapping the connectivity of neurons in the brain (i.e., connectomics) is a challenging problem due to both the number of connections in even the smallest organisms and the nanometer resolution required to resolve them. Because of this,…

Neurons and Cognition · Quantitative Biology 2014-09-08 Ting Zhao , Stephen M Plaza

Whole-brain biological neural networks naturally support the learning and control of whole-body movements. However, the use of brain connectomes as neural network controllers in embodied reinforcement learning remains unexplored. We…

Machine Learning · Computer Science 2026-03-10 Zehao Jin , Yaoye Zhu , Chen Zhang , Yanan Sui

Connectome-constrained neural networks are often evaluated against sparse random controls and then interpreted as evidence that biological graph topology improves learning efficiency. We revisit that claim in a controlled flyvis-based study…

Neurons and Cognition · Quantitative Biology 2026-04-07 Nalin Dhiman

Insects have tiny brains but complicated visual systems for motion perception. A handful of insect visual neurons have been computationally modeled and successfully applied for robotics. How different neurons collaborate on motion…

Neural and Evolutionary Computing · Computer Science 2019-04-16 Qinbing Fu , Cheng Hu , Pengcheng Liu , Shigang Yue

Accurately predicting individual neurons' responses and spatial functional properties in complex visual tasks remains a key challenge in understanding neural computation. Existing whole-brain connectome models of Drosophila often rely on…

Neurons and Cognition · Quantitative Biology 2025-12-09 Jiangping Xie , Ruohan Ren , Xiao Zhou , Ao Zheng , Jiasong Zhu , Wenyu Jiang , Ziran Zhao

Connectomics is an emerging field in neuroscience that aims to reconstruct the 3-dimensional morphology of neurons from electron microscopy (EM) images. Recent studies have successfully demonstrated the use of convolutional neural networks…

Computer Vision and Pattern Recognition · Computer Science 2017-02-27 Shibani Santurkar , David Budden , Alexander Matveev , Heather Berlin , Hayk Saribekyan , Yaron Meirovitch , Nir Shavit

We introduce and analyze a class of neural network models motivated by the Drosophila central complex nervous system, designed to capture the emergence and dynamics of orientation-selective activity bumps. Starting from a biologically…

Dynamical Systems · Mathematics 2026-04-22 S. Ismail , B. Ambrosio , M. A. Aziz-Alaoui , Y. Souleiman

How intelligence emerges from living beings has been a fundamental question in neuroscience. However, it remains largely unanswered due to the complex neuronal dynamics and intricate connections between neurons in real neural systems. To…

Neurons and Cognition · Quantitative Biology 2024-09-04 Xiaoyu Zhang , Pengcheng Yang , Jiawei Feng , Qiang Luo , Wei Lin , Xin Lu

The static synaptic connectivity of neuronal circuits stands in direct contrast to the dynamics of their function. As in changing community interactions, different neurons can participate actively in various combinations to effect behaviors…

Neurons and Cognition · Quantitative Biology 2024-02-29 Luciano Dyballa , Samuel Lang , Alexandra Haslund-Gourley , Eviatar Yemini , Steven W. Zucker

This paper presents a new artificial neuron model capable of learning its receptive field in the topological domain of inputs. The model provides adaptive and differentiable local connectivity (plasticity) applicable to any domain. It…

Neural and Evolutionary Computing · Computer Science 2020-09-08 F. Boray Tek

Despite the progress in deep learning networks, efficient learning at the edge (enabling adaptable, low-complexity machine learning solutions) remains a critical need for defense and commercial applications. We envision a pipeline to…

The connectome is a wiring diagram mapping all the neural connections in the brain. At the cellular level, it provides a map of the neurons and synapses within a part or all of the brain of an organism. In recent years, significant advances…

Neurons and Cognition · Quantitative Biology 2022-06-01 Adrián Hernández , José M. Amigó

The complete connectome of the Drosophila larva brain offers a unique opportunity to investigate whether biologically evolved circuits can support artificial intelligence. We convert this wiring diagram into a Biological Processing Unit…

Neural and Evolutionary Computing · Computer Science 2025-07-16 Siyu Yu , Zihan Qin , Tingshan Liu , Beiya Xu , R. Jacob Vogelstein , Jason Brown , Joshua T. Vogelstein

Cerebellar-like networks, in which input activity patterns are separated by projection to a much higher-dimensional space before classification, are a recurring neurobiological motif, present in the cerebellum, dentate gyrus, insect…

Neurons and Cognition · Quantitative Biology 2026-03-23 William Dorrell , Peter E. Latham

Deep convolutional neural networks (CNNs) have demonstrated impressive performance on visual object classification tasks. In addition, it is a useful model for predication of neuronal responses recorded in visual system. However, there is…

Machine Learning · Statistics 2017-11-15 Qi Yan , Zhaofei Yu , Feng Chen , Jian K. Liu

Anyone who has tried to swat a fly has likely been frustrated by its remarkable agility.This ability stems from its visual neural perception system, particularly the collision-selective neurons within its small brain.For autonomous robots…

Robotics · Computer Science 2025-09-18 Renyuan Liu , Haoting Zhou , Chuankai Fang , Qinbing Fu
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