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In the applications of Boolean networks to modeling biological systems, an important computational problem is the detection of the fixed points of these networks. This is an NP-complete problem in general. There have been various attempts…

Quantitative Methods · Quantitative Biology 2014-04-23 Yi Ming Zou

For a fixed type of Petri nets $\tau$, \textsc{$\tau$-Synthesis} is the task of finding for a given transition system $A$ a Petri net $N$ of type $\tau$ ($\tau$-net, for short) whose reachability graph is isomorphic to $A$ if there is one.…

Computational Complexity · Computer Science 2023-06-22 Ronny Tredup

Petri-nets are a simple formalism for modeling concurrent computation. Recently, they have emerged as a powerful tool for the modeling and analysis of biochemical reaction networks, bridging the gap between purely qualitative and…

Computational Engineering, Finance, and Science · Computer Science 2013-04-11 Faten Nabli , François Fages , Thierry Martinez , Sylvain Soliman

The {\em asynchronous automaton} associated with a Boolean network $f:\{0,1\}^n\to\{0,1\}^n$, considered in many applications, is the finite deterministic automaton where the set of states is $\{0,1\}^n$, the alphabet is $[n]$, and the…

Combinatorics · Mathematics 2023-04-14 Julio Aracena , Adrien Richard , Lilian Salinas

We define and study a class of (random) Boolean constraint satisfaction problems representing minimal feasibility constraints for networks of chemical reactions. The constraints we consider encode, respectively, for hard mass-balance…

Molecular Networks · Quantitative Biology 2014-10-14 Alessandro Seganti , Andrea De Martino , Federico Ricci-Tersenghi

Automata networks are a versatile model of finite discrete dynamical systems composed of interacting entities (the automata), able to embed any directed graph as a dynamics on its space of configurations (the set of vertices, representing…

Discrete Mathematics · Computer Science 2025-09-24 Aliénor Goubault-Larrecq , Kévin Perrot

We investigate classes of systems based on different interaction patterns with the aim of achieving distributability. As our system model we use Petri nets. In Petri nets, an inherent concept of simultaneity is built in, since when a…

Logic in Computer Science · Computer Science 2009-01-05 Rob van Glabbeek , Ursula Goltz , Jens-Wolfhard Schicke

Boolean networks have been used in a variety of settings, as models for general complex systems as well as models of specific systems in diverse fields, such as biology, engineering, and computer science. Traditionally, their properties as…

Dynamical Systems · Mathematics 2024-02-02 Matthew Wheeler , Claus Kadelka , Alan Veliz-Cuba , David Murrugarra , Reinhard Laubenbacher

Theoretical complexity is a vital subfield of computer science that enables us to mathematically investigate computation and answer many interesting queries about the nature of computational problems. It provides theoretical tools to assess…

Computational Complexity · Computer Science 2021-12-23 Mohamed Ghanem , Dauod Siniora

Boolean networks are special types of finite state time-discrete dynamical systems. A Boolean network can be described by a function from an n-dimensional vector space over the field of two elements to itself. A fundamental problem in…

Quantitative Methods · Quantitative Biology 2013-07-03 Yi Ming Zou

We investigate the expressive power of neural networks from the point of view of descriptive complexity. We study neural networks that use floating-point numbers and piecewise polynomial activation functions from two perspectives: 1) the…

Computational Complexity · Computer Science 2025-05-12 Veeti Ahvonen , Damian Heiman , Antti Kuusisto

We investigate how classifiers for Boolean networks (BNs) can be constructed and modified under constraints. A typical constraint is to observe only states in attractors or even more specifically steady states of BNs. Steady states of BNs…

Commutative Algebra · Mathematics 2021-08-20 Robert Schwieger , Matías R. Bender , Heike Siebert , Christian Haase

Despite their apparent simplicity, random Boolean networks display a rich variety of dynamical behaviors. Much work has been focused on the properties and abundance of attractors. We here derive an expression for the number of attractors in…

Molecular Networks · Quantitative Biology 2007-05-23 Björn Samuelsson , Carl Troein

A Boolean control network (BCN) is a discrete-time dynamical system whose variables take values from a binary set $\{0,1\}$. At each time step, each variable of the BCN updates its value simultaneously according to a Boolean function which…

Systems and Control · Computer Science 2019-07-23 Qunxi Zhu , Zuguang Gao , Yang Liu , Weihua Gui

Boolean networks (BNs) are discrete dynamical systems with applications to the modeling of cellular behaviors. In this paper, we demonstrate how the software BoNesis can be employed to exhaustively identify combinations of perturbations…

Systems and Control · Electrical Eng. & Systems 2023-05-03 Loïc Paulevé

As shown in (http://dx.doi.org/10.1101/2020.03.22.998377), the usual update modes of Boolean networks (BNs), including synchronous and (generalized) asynchronous, fail to capture behaviors introduced by multivalued refinements. Thus, update…

Formal Languages and Automata Theory · Computer Science 2020-04-09 Thomas Chatain , Stefan Haar , Juraj Kol{č}ák , Loïc Paulevé

We consider a model for gene regulatory networks that is a modification of Kauffmann's (1969) random Boolean networks. There are three parameters: $n =$ the number of nodes, $r =$ the number of inputs to each node, and $p =$ the expected…

Probability · Mathematics 2009-12-01 Shirshendu Chatterjee , Rick Durrett

Boolean networks (BNs) are widely used to model the qualitative dynamics of biological systems. Besides the logical rules determining the evolution of each component with respect to the state of its regulators, the scheduling of component…

Logic in Computer Science · Computer Science 2019-06-03 Thomas Chatain , Stefan Haar , Juraj Kolčák , Loïc Paulevé , Aalok Thakkar

Boolean control networks (BCNs) are discrete-time dynamical systems with Boolean state-variables and inputs that are interconnected via Boolean functions. BCNs are recently attracting considerable interest as computational models for…

Optimization and Control · Mathematics 2014-07-08 Dmitriy Laschov , Michael Margaliot

In this work, several random Boolean networks (RBN) are generated and analyzed from two characteristics: their time evolution diagram and their transition diagram. For this purpose, its randomness is estimated using three measures, of which…

Information Theory · Computer Science 2024-09-04 Manuel de J. Luevano , Alejandro Puga