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Many research works indicate that EEG bands, specifically the alpha and theta bands, have been potentially helpful cognitive load indicators. However, minimal research exists to validate this claim. This study aims to assess and analyze the…

Signal Processing · Electrical Eng. & Systems 2022-03-03 Bujar Raufi , Luca Longo

Background: Depression is a common mental disorder with societal and economic burden. Current diagnosis relies on self-reports and assessment scales, which have reliability issues. Objective approaches are needed for diagnosing depression.…

Neurons and Cognition · Quantitative Biology 2023-07-18 Sijin Cai , Nanfeng Zhang , Jiaying Zhu , Yanjie Liu , Yongjin Zhou

Progression to dialysis or end-stage renal disease is a rare but clinically important outcome. Clinicians need evidence on how medication exposures influence downstream risk. We constructed a fixed-window EHR cohort (90-day observation,…

Machine Learning · Computer Science 2026-04-28 Kalyani P. Pande , Evan Yang , Bryan Zhu , Sandeep K. Mallipattu , Alisa Yurovsky , Tengfei Ma

Introduction. Low-cost health monitoring devices are increasingly being used for mental health related studies including stress. While cortisol response magnitude remains the gold standard indicator for stress assessment, a growing number…

Human-Computer Interaction · Computer Science 2024-03-12 Gideon Vos , Maryam Ebrahimpour , Liza van Eijk , Zoltan Sarnyai , Mostafa Rahimi Azghadi

The wearable EEG device sector is advancing rapidly, enabling fast and reliable detection of brain activity for investigating brain function and pathology. However, many current EEG systems remain challenging for users with neurological…

Emerging Technologies · Computer Science 2026-01-23 Komal Komal , Frances Cleary , Ram Prasadh Narayanan , John Wells , Marco Buiatti , Louise Bennett

Estimating heterogeneous treatment effect (HTE) for survival outcomes has gained increasing attention, as it captures the variation in treatment efficacy across patients or subgroups in delaying disease progression. However, most existing…

Methodology · Statistics 2025-11-27 Na Bo , Ying Ding

Auxiliary diagnosis of cardiac electrophysiological status can be obtained through the analysis of 12-lead electrocardiograms (ECGs). This work proposes a dual-scale lead-separated transformer with lead-orthogonal attention and…

Computer Vision and Pattern Recognition · Computer Science 2022-11-24 Yang Li , Guijin Wang , Zhourui Xia , Wenming Yang , Li Sun

When treating depression, clinicians are interested in determining the optimal treatment for a given patient, which is challenging given the amount of treatments available. To advance individualized treatment allocation, integrating data…

The electroretinogram (ERG) is a clinical test that records the retina's electrical response to light. The ERG is a promising way to study different neurodevelopmental and neurodegenerative disorders, including autism spectrum disorder…

Predicting a driver's cognitive state, or more specifically, modeling a driver's reaction time (RT) in response to the appearance of a potential hazard warrants urgent research. In the last two decades, the electric field that is generated…

Human-Computer Interaction · Computer Science 2019-05-28 Chun-Hsiang Chuang , Zehong Cao , Po-Tsang Chen , Chih-Sheng Huang , Nikhil R. Pal , Chin-Teng Lin

Pain remains one of the most pressing health challenges, yet its measurement still relies heavily on self-report, limiting monitoring in non-communicative patients and hindering translational research. Neural oscillations recorded with…

Neurons and Cognition · Quantitative Biology 2025-09-16 D. A. Blanco-Mora , A. Dierolf , J. Gonçalves , M. van Der Meulen

In electroencephalogram (EEG) recordings, the presence of interictal epileptiform discharges (IEDs) serves as a critical biomarker for seizures or seizure-like events.Detecting IEDs can be difficult; even highly trained experts disagree on…

The accurate interpretation of Electrocardiogram (ECG) signals is pivotal for diagnosing cardiovascular diseases. Integrating ECG signals with accompanying textual reports further holds immense potential to enhance clinical diagnostics by…

Machine Learning · Computer Science 2025-05-08 Hung Manh Pham , Aaqib Saeed , Dong Ma

Despite extensive standardization, diagnostic interviews for mental health disorders encompass substantial subjective judgment. Previous studies have demonstrated that EEG-based neural measures can function as reliable objective correlates…

Machine Learning · Computer Science 2020-11-19 Garrett Honke , Irina Higgins , Nina Thigpen , Vladimir Miskovic , Katie Link , Sunny Duan , Pramod Gupta , Julia Klawohn , Greg Hajcak

Depression and suicidality affect cognitive and emotional processes, yet objective, task-evoked neural readouts of mental health remain limited. We investigated the spatiotemporal dynamics of affective semantic processing using multivariate…

Emotions are crucial in human life, influencing perceptions, relationships, behaviour, and choices. Emotion recognition using Electroencephalography (EEG) in the Brain-Computer Interface (BCI) domain presents significant challenges,…

Human-Computer Interaction · Computer Science 2025-12-12 Gourav Siddhad , Masakazu Iwamura , Partha Pratim Roy

Parkinsons disease (PD) alters cortical neural dynamics, yet reliable non-invasive electrophysiological biomarkers remain elusive. This study examined whether interpretable EEG features capturing complementary aspects of neural dynamics can…

Neurons and Cognition · Quantitative Biology 2026-04-14 Antonios G. Dougalis

Estimation of conditional average treatment effects (CATEs) plays an essential role in modern medicine by informing treatment decision-making at a patient level. Several metalearners have been proposed recently to estimate CATEs in an…

Applications · Statistics 2022-09-07 Yizhe Xu , Nikolaos Ignatiadis , Erik Sverdrup , Scott Fleming , Stefan Wager , Nigam Shah

Alzheimers disease (AD) is a progressive disorder that affects cognitive brain functions and starts many years before its clinical manifestations. A biomarker that provides a quantitative measure of changes in the brain due to AD in the…

Neurons and Cognition · Quantitative Biology 2022-05-19 Ali H. Al-Nuaimi , Emmanuel Jammeh , Lingfen Sun , Emmanuel Ifeachor

EEG foundation models are typically pretrained on narrow-source clinical archives and evaluated on benchmarks from the same ecosystem, leaving unclear whether representations encode neural physiology or recording-distribution artifacts. We…