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Endoluminal reconstruction using flow diverters represents a novel paradigm for the minimally invasive treatment of intracranial aneurysms. The configuration assumed by these very dense braided stents once deployed within the parent vessel…

Computational Engineering, Finance, and Science · Computer Science 2023-01-23 Beatrice Bisighini , Miquel Aguirre , Marco Evangelos Biancolini , Federica Trovalusci , David Perrin , Stephane Avril , Baptiste Pierrat

A microfluidic device is constructed from PDMS with a single channel having a short section that is a thin flexible membrane, in order to investigate the complex fluid-structure interaction that arises between a flowing fluid and a…

Soft Condensed Matter · Physics 2020-07-03 Debadi Chakraborty , J. Ravi Prakash , Leslie Yeo , James Friend

Blockage of blood flow in arteries or veins by blood clots can lead to serious medical conditions. Mechanical thrombectomy (MT), minimally invasive endovascular procedures that utilize aspiration, stent retriever, or cutting mechanisms for…

Applied Physics · Physics 2024-07-29 Yilong Chang , Qi Li , Shuai Wu , Benjamin Pulli , Darren Samli , Paul Yock , Jeremy J. Heit , Ruike Renee Zhao

We study the dynamics of pattern formation in a minimal model for active mixtures made of microtubules and molecular motors. We monitor the evolution of the (conserved) microtubule density and of the (non-conserved) nematic order parameter,…

Soft Condensed Matter · Physics 2020-05-25 Ivan Maryshev , Alexander Morozov , Andrew B. Goryachev , Davide Marenduzzo

Intracranial aneurysms are the leading cause of hemorrhagic stroke. One of the established treatment approaches is the embolization induced by coil insertion. However, the prediction of treatment and subsequent changed flow characteristics…

Numerical Analysis · Mathematics 2026-05-20 Medeea Horvat , Stephan B. Lunowa , Dmytro Sytnyk , Barbara Wohlmuth

The work analyzes a one-dimensional viscoelastic model of blood vessel growth under nonlinear friction with surroundings, and provides numerical simulations for various growing cases. For the nonlinear differential equations, two sufficient…

Analysis of PDEs · Mathematics 2010-10-18 Chunjing Xie , Xiaoming Zheng

Dynamics of a cluster of chaotic oscillators on a network are studied using coupled maps. By introducing the association schemes, we obtain coupling strength in the adjacency matrices form, which satisfies Markov matrices property. We…

Chaotic Dynamics · Physics 2018-02-19 S. Behnia , M. Yahyavi , R. Habibpourbisafar

In this paper, our aim is to present (1) an embedded fracture model (EFM) for coupled flow and mechanics problem based on the dual continuum approach on the fine grid and (2) an upscaled model for the resulting fine grid equations. The…

Numerical Analysis · Mathematics 2018-11-14 Maria Vasilyeva , Eric T. Chung , Yalchin Efendiev , Jihoon Kim

Rupture of intracranial aneurysms results in severe subarachnoidal hemorrhage, which is associated with high morbidity and mortality. Neurointerventional occlusion of the aneurysm through coiling has evolved to a therapeutical standard. The…

Computational Engineering, Finance, and Science · Computer Science 2024-03-12 Julian Schwarting , Fabian Holzberger , Markus Muhr , Martin Renz , Tobias Boeckh-Behrens , Barbara Wohlmuth , Jan Kirschke

This text presents one of the first successful applications of a rare events method for the study of multistability in a turbulent flow without stochastic energy injection. The trajectories of collapse of turbulence in plane Couette flow,…

Fluid Dynamics · Physics 2021-11-29 Joran Rolland

During cell division, sister chromatids are segregated by the mitotic spindle, a bipolar assembly of interdigitating antiparallel polar filaments called microtubules. Establishing a stable overlap region is essential for maintenance of…

Biological Physics · Physics 2015-09-16 D. Johann , D. Goswami , K. Kruse

Soluble alpha-amylases play an important role in the catabolism of polysaccharides. In this work, we show that the enzyme can interact with the lipid membrane and further alter its mechanical properties. Vesicle fluctuation spectroscopy is…

The field of connectomics faces unprecedented "big data" challenges. To reconstruct neuronal connectivity, automated pixel-level segmentation is required for petabytes of streaming electron microscopy data. Existing algorithms provide…

Coupling is a widely used technique in the theoretical study of interacting stochastic processes. In this paper I present an example demonstrating its usefulness also in the efficient computer simulation of such processes. I first describe…

Populations and Evolution · Quantitative Biology 2012-04-16 Ilmari Karonen

The micromixing process in microfluidic devices is of central importance in quite a few applications, with microfluidic studies on carbon capture and environmental monitoring being two examples. High surface area to volume ratio in…

Fluid Dynamics · Physics 2025-11-21 Seyed Shahriar Riazi , Seyed Mostafa Hosseinalipour

In this paper we develop a general framework for constructing and analysing coupled Markov chain Monte Carlo samplers, allowing for both (possibly degenerate) diffusion and piecewise deterministic Markov processes. For many performance…

Probability · Mathematics 2018-06-29 N. Nuesken , G. A. Pavliotis

The asymptotic derivation of a new family of one-dimensional, weakly nonlinear and weakly dispersive equations that model the flow of an ideal fluid in an elastic vessel is presented. Dissipative effects due to the viscous nature of the…

Fluid Dynamics · Physics 2020-02-20 Dimitrios Mitsotakis , Denys Dutykh , Li Qian

Medical therapy for patients with severe heart disease often relies on left ventricular assist devices (LVADs). It is an ongoing topic of research how complications like stagnation and thrombosis can be prevented by using artificial…

Fluid Dynamics · Physics 2025-03-31 Maximilian R. Schuster , Nico Dirkes , Fabian Key , Stefanie Elgeti , Marek Behr

Numerical predictions of blood flow and hemodynamic properties through a stenotic and aneurysmal rigid artery are studied in the presence of blood clot at constricted area. Finite element method has been used to solve the steady partial…

Fluid Dynamics · Physics 2020-05-20 Mohammed Nasir Uddin , M. Monir Uddin , Md. Monjarul Alam

The use of nanoparticles for targeted drug delivery, especially in diseased arteries, is a novel procedure. We are incorporating nanoparticles into blood vessels using a catheter, which could potentially deliver drugs precisely to affected…

Fluid Dynamics · Physics 2023-08-31 Surabhi Rathore , Dasari Srikanth