Related papers: Modelling pulsatile blood flow through surgically …
Understanding the physics of blood is challenging due to its nature as a suspension of soft particles and the fact that typical problems involve different scales. This is valid also for numerical investigations. In fact, many computational…
Ultrasound localization microscopy (ULM) refers to a promising medical imaging modality that systematically leverages the advantages of contrast-enhanced ultrasound (CEUS) to surpass the diffraction barrier and delineate the microvascular…
We consider the Navier-Stokes equations in a channel with a narrowing and walls of varying curvature. By applying the empirical interpolation method to generate an affine parameter dependency, the offline-online procedure can be used to…
Intracranial aneurysms remain a major cause of neurological morbidity and mortality worldwide, where rupture risk is tightly coupled to local hemodynamics particularly wall shear stress and oscillatory shear index. Conventional…
We present a model for the spontaneous formation of a striated pattern in polymerizing microtubule solutions. It describes the buckling of a single microtubule (MT) bundle within an elastic network formed by other similarly aligned and…
Super-resolution ultrasound imaging relies on the sub-wavelength localization of microbubble contrast agents. By tracking individual microbubbles, the velocity and flow within microvessels can be estimated. However, a 2D super-resolution…
The blood vascular system consists of blood vessels such as arteries, arterioles, capillaries and veins that convey blood throughout the body. The pressure difference which exists between the ends of the vessels provides the living force…
The possible disruption of a microtubule during mitosis can control the duplication of a cancer cell. Cancer detection and treatment may be possible based on the detection and control of microtubule mechanical oscillations in cells through…
Magnetic reconnection is a process that changes magnetic field topology in highly conducting fluids. Within the standard Sweet-Parker model, this process would be too slow to explain observations (e.g. solar flares). In reality, the process…
Super-Resolution Ultrasound (SRUS) imaging through localising and tracking microbubbles, also known as Ultrasound Localisation Microscopy (ULM), has demonstrated significant potential for reconstructing microvasculature and flows with…
Transpiration cooling is an active thermal protection system of increasing interest in aerospace applications wherein a coolant is effused through a porous wall into a hot external flow. The present work focuses on the interaction between…
Several cardiovascular diseases are caused from localised abnormal blood flow such as in the case of stenosis or aneurysms. Prevailing theories propose that the development is caused by abnormal wall-shear stress in focused areas.…
We present a phenomenological model for the mixing length used in turbulence models. It has the advantage of naturally accounting for the object's geometry while satisfying the standard symmetries of the Navier-Stokes equations. We employ…
Long, shallow microchannels embedded in thick soft materials are widely used in microfluidic devices for lab-on-a-chip applications. However, the bulging effect caused by fluid--structure interactions between the internal viscous flow and…
Cardiovascular disease arises from interactions between inherited risk, molecular programmes, and tissue-scale remodelling that are observed clinically through imaging. Health systems now routinely generate large volumes of cardiac MRI, CT…
Presented are two techniques that are designed to help streamline the discretization of complex vascular geometries within the numerical modeling process. The first method integrates multiple software tools into a single pipeline which can…
A noteworthy aspect in blood flow modeling is the definition of the mechanical interaction between the fluid flow and the biological structure that contains it, namely the vessel wall. It has been demonstrated that the addition of a viscous…
We study a mesoscopic model for the flow of amorphous solids. The model is based on the key features identified at the microscopic level, namely peri- ods of elastic deformation interspersed with localised rearrangements of parti- cles that…
Human blood flow is a multi-scale problem: in first approximation, blood is a dense suspension of plasma and deformable red cells. Physiological vessel diameters range from about one to thousands of cell radii. Current computational models…
The circulatory system, comprising the heart and blood vessels, is vital for nutrient transport, waste removal, and homeostasis. Traditional computational models often treat cardiac electromechanics and blood flow dynamics separately,…