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Modeling coupled systems of free flow adjacent to a porous medium by means of fully resolved Navier-Stokes equations is limited by the immense computational cost and is thus only feasible for relatively small domains. Model reduction allows…

Computational Physics · Physics 2019-08-07 Kilian Weishaupt , Alexandros Terzis , Ioannis Zarikos , Guang Yang , Matthijs de Winter , Rainer Helmig

Multiphase shear flows often show banded structures that affect the global behavior of complex fluids e.g. in microdevices. Here we investigate numerically the banding of emulsions, i.e. the formation of regions of high and low volume…

Fluid Dynamics · Physics 2020-04-30 Francesco De Vita , Marco Edoardo Rosti , Sergio Caserta , Luca Brandt

In this work we study the hemodynamics in a stented artery connected either to a collateral artery or to an aneurysmal sac. The blood flow is driven by the pressure drop. Our aim is to characterize the flow-rate and the pressure in the…

Analysis of PDEs · Mathematics 2010-07-07 Vuk Milisic

One route to improved predictive modeling of magnetically confined fusion reactors is to couple transport solvers with direct numerical simulations (DNS) of turbulence, rather than with surrogate models. An additional challenge presented by…

Plasma Physics · Physics 2018-07-16 Jeffrey B. Parker , Lynda L. LoDestro , Alejandro Campos

A recent conceptual model of tumor-driven angiogenesis including branching, elongation, and anastomosis of blood vessels captures some of the intrinsic multiscale structures of this complex system, yet allowing to extract a deterministic…

Tissues and Organs · Quantitative Biology 2016-02-24 F. Terragni , M. Carretero , V. Capasso , L. L. Bonilla

The aim of this paper is to investigate the asymptotic behavior of a biphase tumor fluid flow derived by 2-scale homogenisation techniques in recent works. This biphase fluid flow model accounts for the capillary wall permeability, and the…

Analysis of PDEs · Mathematics 2021-01-12 Cristina Vaghi , Sébastien Benzekry , Clair Poignard

Ultrasound localization microscopy offers new radiation-free diagnostic tools for vascular imaging deep within the tissue. Sequential localization of echoes returned from inert microbubbles with low-concentration within the bloodstream…

Medical Physics · Physics 2018-04-11 Oren Solomon , Ruud J. G. van Sloun , Hessel Wijkstra , Massimo Mischi , Yonina C. Eldar

A sparse modeling approach is proposed for analyzing scanning tunneling microscopy topography data, which contains numerous peaks corresponding to surface atoms. The method, based on the relevance vector machine with $\mathrm{L}_1$…

Data Analysis, Statistics and Probability · Physics 2018-03-13 Masamichi J. Miyama , Koji Hukushima

Damage to the blood vessel triggers formation of a hemostatic plug, which is meant to prevent bleeding, yet the same phenomenon may result in a total blockade of a blood vessel by a thrombus, causing severe medical conditions. Here, we show…

Fluid Dynamics · Physics 2015-07-23 Aleksey V. Belyaev , Mikhail A. Panteleev , Fazly I. Ataullakhanov

Internal haemorrhage, often leading to cardio-vascular arrest happens to be one of the prime sources of high fatality rates in mammals. We propose a simplistic model of fluid flow to specify the location of the haemorrhagic spots, which, if…

Soft Condensed Matter · Physics 2013-04-01 Amit K. Chattopadhyay , Shreekantha Sil

Fast and realistic coupling of blood flow and vessel wall is of great importance to virtual surgery. In this paper, we propose a novel data-driven coupling method that formulates physics-based blood flow simulation as a regression problem,…

Graphics · Computer Science 2019-01-25 Xuejie Mai , Zhiyong Yuan , Qianqian Tong , Tianchen Yuan , Jianhui Zhao

In the field of biomedicine magnetic beads are used for drug delivery and to treat hyperthermia. Here we propose to use self-organized bead structures to isolate circulating tumor cells using lab-on-chip technologies. Typically blood flows…

Complex fluids such as emulsions, colloidal gels, polymer or surfactant solutions are all characterized by the existence of a "microstructure" which may couple to an external flow on timescales that are easily probed in experiments. Such a…

Soft Condensed Matter · Physics 2015-02-11 Christophe Perge , Marc-Antoine Fardin , Sebastien Manneville

We present a novel machine learning based surrogate modeling method for predicting spatially resolved 3D microstructure evolution of polycrystalline materials under uniaxial tensile loading. Our approach is orders of magnitude faster than…

Materials Science · Physics 2020-05-05 Anup Pandey , Reeju Pokharel

Blood vessel constriction is simulated with particle-based method using a molecular dynamics authoring software known as Molecular Workbench (WM). Blood flow and vessel wall, the only components considered in constructing a blood vessel,…

Biological Physics · Physics 2014-04-01 Mohamad Rendi , Suprijadi , Sparisoma Viridi

We present a new method for modeling tissue perfusion on the capillary scale. The microvasculature is represented by a network of one-dimensional vessel segments embedded in the extra-vascular space. Vascular and extra-vascular space…

Computational Physics · Physics 2020-03-23 Timo Koch , Martin Schneider , Rainer Helmig , Patrick Jenny

Accurate and integrable control of different flows within microfluidic channels is crucial to further development of lab-on-a-chip and fully integrated adaptable structures. Here we introduce a flexible microactuator that buckles at a high…

Fluid Dynamics · Physics 2016-04-20 Behrouz Tavakol , Douglas P. Holmes

Minimally invasive medical procedures, such as endovascular catheterization, have drastically reduced procedure time and associated complications. However, many regions inside the body, such as in the brain vasculature, still remain…

Applied Physics · Physics 2021-01-27 Lucio Pancaldi , Pietro Dirix , Adele Fanelli , Diego Ghezzi , Mahmut Selman Sakar

We performed numerical simulations of blood flow in arteries with a variable stiffness and cross-section at rest using a finite volume method coupled with a hydrostatic reconstruction of the variables at the interface of each mesh cell. The…

Numerical Analysis · Mathematics 2015-09-15 Olivier Delestre , Arthur Ghigo , Jose-Maria Fullana , Pierre-Yves Lagrée

Mathematical models are widely recognized as a valuable tool for cardiovascular diagnosis and the study of circulatory diseases, especially to obtain data that require otherwise invasive measurements. To correctly simulate body…