Related papers: Modelling pulsatile blood flow through surgically …
The unacceptably high stroke rate of HeartMate III VAD without signs of adherent pump thrombosis is hypothesized to be the result of the thrombi originating on the inflow cannula, ingesting and ejecting emboli from the VAD. Therefore,…
The assisted tunneling of a metastable state between barriers is investigated analytically by means of a simplified one dimensional model. A time dependent perturbation changes the pole spectrum of the wave function introducing a larger…
The spread of metastases is a crucial process in which some questions remain unanswered. In this work, we focus on tumor cells circulating in the bloodstream, the so-called Circulating Tumor Cells (CTCs). Our aim is to characterize their…
The study of viscous fluid flow coupled with rigid or deformable solids has many applications in biological and engineering problems, e.g., blood cell transport, drug delivery, and particulate flow. We developed a partitioned approach to…
In this paper, we present a mathematical and numerical model for blood solidification and its rupture in stenosed arteries. The interaction between the blood flow and an existing stenosis in the arterial wall is modeled as a three…
The transitional flow which initiates within the junction (anastomosis) of an arteriovenous fistula (AVF) is known to be a contributing factor in the onset of vascular disease. A novel treatment method involving the implantation of a…
Background and Objective: The role of red blood cell dynamics is emphasised in certain cardiovascular diseases, and thus needs to be closely studied. A multiphase model of blood flow allows the resolution of locally varying density of red…
Thrombolytic occlusions in stroke, pulmonary embolism and the peripheral vasculature are increasingly treated with aspiration, a catheter-based approach that employs suction to extract clots through a hollow catheter lumen. Unfortunately,…
Cardiac disease and clinical intervention may both lead to an increased risk for thrombosis events due to modified blood flow in the heart, and thereby a change in the mechanical stimuli of blood cells passing through the chambers of the…
Asymptotic post-buckling theory is applied to sizing and topology optimization of trusses and frames, exploring its potential and current computational difficulties. We show that a designs' post-buckling response can be controlled by…
Mechanisms for non-invasive target drug delivery using microbubbles and ultrasound have attracted growing interest. Microbubbles can be loaded with a therapeutic payload and tracked via ultrasound imaging to selectively release their…
In this paper, we introduce an adapted one-dimensional (1D) reduced model aimed at analyzing blood flow within stenosed arteries. Differing from the prevailing 1D model \cite{Formaggia2003, Sherwin2003_2, Sherwin2003, Quarteroni2004,…
This paper presents the coupled model of a hydraulic fracturing and proppant transport. The former is described in terms of enhanced pseudo-3D model that considers height growth across two symmetric stress barriers, while the latter is…
When a blood vessel ruptures or gets inflamed, the human body responds by rapidly forming a clot to restrict the loss of blood. Platelets aggregation at the injury site of the blood vessel occurring via platelet-platelet adhesion, tethering…
In this work, we introduce an algorithmic approach to generate microvascular networks starting from larger vessels that can be reconstructed without noticeable segmentation errors. Contrary to larger vessels, the reconstruction of…
Super-resolution ultrasound can image microvascular structure and flow at sub-wave-diffraction resolution based on localising and tracking microbubbles. Currently, tracking microbubbles accurately under limited imaging frame rates and high…
High-precision micromanipulation techniques, including optical tweezers and hydrodynamic trapping, have garnered wide-spread interest. Recent advances in optofluidic multiplexed assembly and microrobotics demonstrate significant progress,…
Wall-bounded turbulent flows can be challenging to measure within experiments due to the breadth of spatial and temporal scales inherent in such flows. Instrumentation capable of obtaining time-resolved data (e.g., Hot-Wire Anemometers)…
In the last years, medical computer simulation has seen a great growth in several scientific branches, from modelling to numerical methods, going through computer science. The main goals of this incipient discipline are testing hypotheses…
Vascular anastomosis, the surgical connection of blood vessels, is essential in procedures such as organ transplants and reconstructive surgeries. The precision required limits accessibility due to the extensive training needed, with manual…