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Joinpoint regression is used to determine the number of segments needed to adequately explain the relationship between two variables. This methodology can be widely applied to real problems, but we focus on epidemiological data, the main…

Applications · Statistics 2011-12-08 Miguel A. Martinez-Beneito , Gonzalo García-Donato , Diego Salmerón

In the aftermath of the COVID-19 pandemic, empirical data have revealed that large-scale health crises not only cause immediate disruptions in mortality dynamics but also have persistent effects that may last for several years. Existing…

Applications · Statistics 2026-03-26 Yanxin Liu , Kenneth Q. Zhou

Heterogeneity is a dominant factor in the behaviour of many biological processes. Despite this, it is common for mathematical and statistical analyses to ignore biological heterogeneity as a source of variability in experimental data.…

Worldwide, many millions of people die suddenly and unexpectedly each year, either with or without a prior history of cardiovascular disease. Such events are sparse (once in a lifetime), many victims will not have had prior investigations…

Machine Learning · Computer Science 2023-09-06 Yola Jones , Fani Deligianni , Jeff Dalton , Pierpaolo Pellicori , John G F Cleland

We propose a stochastic model for evolution. Births and deaths of species occur with constant probabilities. Each new species is associated with a fitness sampled from the uniform distribution on [0,1]. Every time there is a death event…

Probability · Mathematics 2010-11-09 Herve Guiol , Fabio P. Machado , Rinaldo B. Schinazi

Machine learning models that aim to predict dementia onset usually follow the classification methodology ignoring the time until an event happens. This study presents an alternative, using survival analysis within the context of machine…

Machine Learning · Computer Science 2023-06-21 Daniel Stamate , Henry Musto , Olesya Ajnakina , Daniel Stahl

In this article we suggest a new statistical approach considering survival heterogeneity as a breakpoint model in an ordered sequence of time to event variables. The survival responses need to be ordered according to a numerical covariate.…

Applications · Statistics 2016-09-26 Olivier Bouaziz , Grégory Nuel

Control rate regression is a diffuse approach to account for heterogeneity among studies in meta-analysis by including information about the outcome risk of patients in the control condition. Correcting for the presence of measurement error…

Methodology · Statistics 2018-03-29 Annamaria Guolo

This paper proposes a linear categorical random coefficient model, in which the random coefficients follow parametric categorical distributions. The distributional parameters are identified based on a linear recurrence structure of moments…

Econometrics · Economics 2023-03-01 Zhan Gao , M. Hashem Pesaran

We develop a formalism for insurance profit optimisation for the in-force business constraint by regulatory and risk policy related requirements. This approach is applicable to Life, P&C and Reinsurance businesses and applies in all…

Statistical Finance · Quantitative Finance 2025-11-19 Jan Maelger

This paper considers the problem of forecasting mortality rates. A large number of models have already been proposed for this task, but they generally have the disadvantage of either estimating the model in a two-step process, possibly…

Applications · Statistics 2023-05-26 Patrik Andersson , Mathias Lindholm

The current outbreak of COVID-19 has called renewed attention to the need for sound statistical analysis for monitoring mortality patterns and trends over time. Excess mortality has been suggested as the most appropriate indicator to…

Applications · Statistics 2020-10-13 Patrizio Vanella , Ugofilippo Basellini , Berit Lange

The existing life table method needs to calculate the age-specific mortality first, not only has too many and complicated calculation steps, but also introduces the multiple approximation to bring error. This paper redefines the probability…

Other Quantitative Biology · Quantitative Biology 2020-04-21 Weidong Huang

The paper provides a stochastic model useful for assessing the capital requirement for demographic risk. The model extends to the market consistent context classical methodologies developed in a local accounting framework. In particular we…

Risk Management · Quantitative Finance 2022-01-12 Gian Paolo Clemente , Francesco Della Corte , Nino Savelli

Model averaging techniques in the actuarial literature aim to forecast future longevity appropriately by combining forecasts derived from various models. This approach often yields more accurate predictions than those generated by a single…

Applications · Statistics 2025-10-28 Giovanna Bimonte , Maria Russolillo , Han Lin Shang , Yang Yang

Multiple species in the ecosystem are believed to compete cyclically for survival and thus maintain balance in nature. Stochasticity has also an inevitable role in this dynamics. Considering these attributes of nature, the stochastic…

Populations and Evolution · Quantitative Biology 2020-08-05 Sirshendu Bhattacharyya , Pritam Sinha , Rina De , Chittaranjan Hens

Accuracy and interpretability of a (non-life) insurance pricing model are essential qualities to ensure fair and transparent premiums for policy-holders, that reflect their risk. In recent years, the classification and regression trees…

Machine Learning · Statistics 2023-12-04 Yaojun Zhang , Lanpeng Ji , Georgios Aivaliotis , Charles Taylor

Binomial data with unknown sizes often appear in biological and medical sciences. The previous methods either use the Poisson approximation or the quasi-likelihood approach. A full likelihood approach is proposed by treating unknown sizes…

Statistics Theory · Mathematics 2007-06-13 Wei Zhang

Accurate simulation of complex physical systems enables the development, testing, and certification of control strategies before they are deployed into the real systems. As simulators become more advanced, the analytical tractability of the…

Robotics · Computer Science 2020-05-27 Lucas Barcelos , Rafael Oliveira , Rafael Possas , Lionel Ott , Fabio Ramos

New and efficient methods based on noise addition to protect the confidentiality in population statistics have been developed, tested and applied in census production by various members of the European Statistical System over the past…

Methodology · Statistics 2026-02-04 Fabian Bach
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