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Large pools of synthetic DNA molecules have been recently used to reliably store significant volumes of digital data. While DNA as a storage medium has enormous potential because of its high storage density, its practical use is currently…

Data Structures and Algorithms · Computer Science 2021-02-25 Konstantin Makarychev , Miklos Z. Racz , Cyrus Rashtchian , Sergey Yekhanin

DNA pattern matching is essential for many widely used bioinformatics applications. Disease diagnosis is one of these applications, since analyzing changes in DNA sequences can increase our understanding of possible genetic diseases. The…

Hardware Architecture · Computer Science 2022-06-01 Jinane Bazzi , Jana Sweidan , Mohammed E. Fouda , Rouwaida Kanj , Ahmed M. Eltawil

The Gene or DNA sequence in every cell does not control genetic properties on its own; Rather, this is done through translation of DNA into protein and subsequent formation of a certain 3D structure. The biological function of a protein is…

Computational Engineering, Finance, and Science · Computer Science 2019-05-30 Leila Khalatbari , Mohammad Reza Kangavari , Saeid Hosseini , Hongzhi Yin , Ngai-Man Cheung

To overcome range anxiety problem of Electric Vehicles (EVs), an accurate real-time energy consumption estimation is necessary, which can be used to provide the EV's driver with information about the remaining range in real-time. A hybrid…

Signal Processing · Electrical Eng. & Systems 2021-04-22 Shatrughan Modi , Jhilik Bhattacharya , Prasenjit Basak

This work introduces a novel interpretable machine learning method called Mixture of Decision Trees (MoDT). It constitutes a special case of the Mixture of Experts ensemble architecture, which utilizes a linear model as gating function and…

Machine Learning · Computer Science 2022-11-29 Simeon Brüggenjürgen , Nina Schaaf , Pascal Kerschke , Marco F. Huber

Model-based clustering is widely used for identifying and distinguishing types of diseases. However, modern biomedical data coming with high dimensions make it challenging to perform the model estimation in traditional cluster analysis. The…

Methodology · Statistics 2025-07-22 Kazeem Kareem , Fan Dai

Machine learning (ML) algorithms have been employed in the problem of classifying signal and background events with high accuracy in particle physics. In this paper, we compare the performance of a widespread ML technique, namely,…

High Energy Physics - Phenomenology · Physics 2017-06-01 Alexandre Alves

For the first time, we enable the execution of hybrid machine learning methods on real quantum computers with 100 data samples and real-device-based simulations with 5,000 data samples, thereby outperforming the current state of research of…

Currently, data-driven discovery in biological sciences resides in finding segmentation strategies in multivariate data that produce sensible descriptions of the data. Clustering is but one of several approaches and sometimes falls short…

Quantitative Methods · Quantitative Biology 2022-08-12 Richard Tjörnhammar

We introduce a novel Bayesian hybrid matrix factorisation model (HMF) for data integration, based on combining multiple matrix factorisation methods, that can be used for in- and out-of-matrix prediction of missing values. The model is very…

Machine Learning · Statistics 2017-04-18 Thomas Brouwer , Pietro Lió

The field of drug discovery hinges on the accurate prediction of binding affinity between prospective drug molecules and target proteins, especially when such proteins directly influence disease progression. However, estimating binding…

Artificial intelligence is one of the drivers of modern technological development. The current approach to the development of intelligent systems is data-centric. It has several limitations: it is fundamentally impossible to collect data…

Artificial Intelligence · Computer Science 2021-12-10 Kirill Krinkin , Yulia Shichkina , Andrey Ignatyev

DNA is a leading candidate as the next archival storage media due to its density, durability and sustainability. To read (and write) data DNA storage exploits technology that has been developed over decades to sequence naturally occurring…

Emerging Technologies · Computer Science 2022-05-12 Jasmine Quah , Omer Sella , Thomas Heinis

In order to speed-up classification models when facing a large number of categories, one usual approach consists in organizing the categories in a particular structure, this structure being then used as a way to speed-up the prediction…

Machine Learning · Computer Science 2015-11-26 Aurélia Léon , Ludovic Denoyer

The past years have seen a considerable increase in cancer cases. However, a cancer diagnosis is often complex and depends on the types of images provided for analysis. It requires highly skilled practitioners but is often time-consuming…

Image and Video Processing · Electrical Eng. & Systems 2022-10-24 Solene Bechelli

Training efficiency is one of the main problems for Neural Machine Translation (NMT). Deep networks need for very large data as well as many training iterations to achieve state-of-the-art performance. This results in very high computation…

Computation and Language · Computer Science 2017-10-04 Dakun Zhang , Jungi Kim , Josep Crego , Jean Senellart

A mutation in a protein-coding gene in DNA can alter the protein structure coded by the same gene. Structurally altered proteins usually lose their functions and sometimes gain an undesirable function instead. These types of mutations and…

Quantitative Methods · Quantitative Biology 2017-08-29 Kaan Aygen , Berkay Celik , Umut Eser

This work presents a novel technique that integrates the methodologies of machine learning and system identification to solve multiclass problems. Such an approach allows to extract and select sets of representative features with reduced…

Machine Learning · Computer Science 2021-06-09 P. H. O. Silva , A. S. Cerqueira , E. G. Nepomuceno

Statistically resolving the underlying haplotype pair for a genotype measurement is an important intermediate step in gene mapping studies, and has received much attention recently. Consequently, a variety of methods for this problem have…

Machine Learning · Computer Science 2007-10-29 Matti Kääriäinen , Niels Landwehr , Sampsa Lappalainen , Taneli Mielikäinen

Molecular and genomic properties are critical in selecting cancer treatments to target individual tumors, particularly for immunotherapy. However, the methods to assess such properties are expensive, time-consuming, and often not routinely…

Image and Video Processing · Electrical Eng. & Systems 2022-11-29 Heather D. Couture
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