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Objectives We aimed to evaluate the diagnostic performance of deep learning (DL)-based radiomics models for the noninvasive prediction of isocitrate dehydrogenase (IDH) mutation and 1p/19q co-deletion status in glioma patients using MRI…

Quantitative Methods · Quantitative Biology 2025-08-19 Somayeh Farahani , Marjaneh Hejazi , Mehnaz Tabassum , Antonio Di Ieva , Neda Mahdavifar , Sidong Liu

Glioblastoma is the most malignant form of brain cancer. It is extremely invasive; the mechanisms that govern invasion are not well understood. To better understand the process of invasion, we conducted an in vitro experiment in which a 3d…

Cell Behavior · Quantitative Biology 2007-05-23 A M Stein , D A Vader , T S Deisboeck , E A Chiocca , L M Sander , D A Weitz

This study estimated the planning quality of intensity-modulated radiotherapy in 42 lung cancer cases to provide preliminary data for the development of a planning quality assurance algorithm. Organs in or near the thoracic cavity…

Medical Physics · Physics 2015-03-11 Jihye Koo , Myonggeun Yoon , Weon Kuu Chung , Dong Wook Kim

Asymmetric partition of fate determinants during cell division is a hallmark of cell differentiation. Recent work suggested that such a mechanism is hijacked by cancer cells to increase both their phenotypic heterogeneity and plasticity and…

Spinal cord tumors lead to neurological morbidity and mortality. Being able to obtain morphometric quantification (size, location, growth rate) of the tumor, edema, and cavity can result in improved monitoring and treatment planning. Such…

Image and Video Processing · Electrical Eng. & Systems 2021-03-31 Andreanne Lemay , Charley Gros , Zhizheng Zhuo , Jie Zhang , Yunyun Duan , Julien Cohen-Adad , Yaou Liu

Glioma is the most common and aggressive brain tumor. Magnetic resonance imaging (MRI) plays a vital role to evaluate tumors for the arrangement of tumor surgery and the treatment of subsequent procedures. However, the manual segmentation…

Image and Video Processing · Electrical Eng. & Systems 2022-03-23 Wenbo Zhang , Guang Yang , He Huang , Weiji Yang , Xiaomei Xu , Yongkai Liu , Xiaobo Lai

Lung adenocarcinoma is a morphologically heterogeneous disease, characterized by five primary histologic growth patterns. The quantity of these patterns can be related to tumor behavior and has a significant impact on patient prognosis. In…

Image and Video Processing · Electrical Eng. & Systems 2024-05-17 Arwa Al-Rubaian , Gozde N. Gunesli , Wajd A. Althakfi , Ayesha Azam , Nasir Rajpoot , Shan E Ahmed Raza

Osteosarcoma, the most common primary bone cancer, often requires accurate necrosis assessment from whole slide images (WSIs) for effective treatment planning and prognosis. However, manual assessments are subjective and prone to…

Computer Vision and Pattern Recognition · Computer Science 2025-01-06 Manh Duong Nguyen , Dac Thai Nguyen , Trung Viet Nguyen , Homi Yamada , Huy Hieu Pham , Phi Le Nguyen

Existing approaches to modeling the dynamics of brain tumor growth, specifically glioma, employ biologically inspired models of cell diffusion, using image data to estimate the associated parameters. In this work, we propose an alternative…

Neurogliomas are among the most aggressive forms of cancer, presenting considerable challenges in both treatment and monitoring due to their unpredictable biological behavior. Magnetic resonance imaging (MRI) is currently the preferred…

Image and Video Processing · Electrical Eng. & Systems 2025-03-06 Shenghao Zhu , Yifei Chen , Shuo Jiang , Weihong Chen , Chang Liu , Yuanhan Wang , Xu Chen , Yifan Ke , Feiwei Qin , Changmiao Wang , Zhu Zhu

Oral squamous cell carcinomas (OSCC) are the 6th most common cancer and the diagnosis is often belated for a curative treatment. The reliable and early differentiation between healthy and diseased cells is the main aim of this study in…

Identifying concentrations of components from an observed mixture is a fundamental problem in signal processing. It has diverse applications in fields ranging from hyperspectral imaging to denoising biomedical sensors. This paper focuses on…

Computational Engineering, Finance, and Science · Computer Science 2016-11-17 Shahin Mohammadi , Neta Zuckerman , Andrea Goldsmith , Ananth Grama

We present deep H-band surface photometry and analysis of 40 Local Volume galaxies, a sample primarily composed of dwarf irregulars in the Cen A group, obtained using the IRIS2 detector at the 3.9m Anglo-Australian Telescope. We probe to a…

Astrophysics of Galaxies · Physics 2014-08-14 T. Young , H. Jerjen , Á. R. López-Sánchez , B. S. Koribalski

Glioma is a common type of brain tumor, and accurate detection of it plays a vital role in the diagnosis and treatment process. Despite advances in medical image analyzing, accurate tumor segmentation in brain magnetic resonance (MR) images…

Image and Video Processing · Electrical Eng. & Systems 2020-02-27 Fateme Mostafaie , Reihaneh Teimouri , Zahra Nabizadeh , Nader Karimi , Shadrokh Samavi

Background and Purpose: Glioma segmentation is crucial for clinical decisions and treatment planning. Uncertainty quantification methods, including conformal prediction (CP), can enhance segmentation models reliability. This study aims to…

Image and Video Processing · Electrical Eng. & Systems 2025-03-03 Danial Elyassirad , Benyamin Gheiji , Mahsa Vatanparast , Amir Mahmoud Ahmadzadeh , Shahriar Faghani

Gliomas are aggressive brain tumors that require accurate imaging-based diagnosis, with segmentation playing a critical role in evaluating morphology and treatment decisions. Manual delineation of gliomas is time-consuming and prone to…

Image and Video Processing · Electrical Eng. & Systems 2025-12-02 Cecilia Diana-Albelda , Roberto Alcover-Couso , Álvaro García-Martín , Jesus Bescos , Marcos Escudero-Viñolo

Central nervous system (CNS) tumors come with the vastly heterogeneous histologic, molecular and radiographic landscape, rendering their precise characterization challenging. The rapidly growing fields of biophysical modeling and radiomics…

Quantitative Methods · Quantitative Biology 2020-06-30 Andreas Mang , Spyridon Bakas , Shashank Subramanian , Christos Davatzikos , George Biros

Here we present the University of California San Francisco Preoperative Diffuse Glioma MRI (UCSF-PDGM) dataset. The UCSF-PDGM dataset includes 500 subjects with histopathologically-proven diffuse gliomas who were imaged with a standardized…

A glioma is a malignant brain tumor that seriously affects cognitive functions and lowers patients' life quality. Segmentation of brain glioma is challenging because of interclass ambiguities in tumor regions. Recently, deep learning…

Image and Video Processing · Electrical Eng. & Systems 2022-11-02 Yiming Yao , Peisheng Qian , Ziyuan Zhao , Zeng Zeng

Background: Accurate segmentation of diffuse large B-cell lymphoma (DLBCL) lesions is challenging due to their complex patterns in medical imaging. Objective: This study aims to develop a precise segmentation method for DLBCL using…

Image and Video Processing · Electrical Eng. & Systems 2024-09-10 Huan Huang , Liheng Qiu , Shenmiao Yang , Longxi Li , Jiaofen Nan , Yanting Li , Chuang Han , Fubao Zhu , Chen Zhao , Weihua Zhou