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Diffuse gliomas are highly infiltrative tumors whose early diagnosis and follow-up usually rely on magnetic resonance imaging (MRI). However, the limited sensitivity of this technique makes it impossible to directly assess the extent of the…

Collective cell movement, characterized by multiple cells that are in contact for substantial periods of time and undergo correlated motion, plays a central role in cancer and embryogenesis. Recent imaging experiments have provided…

Biological Physics · Physics 2020-06-03 Sumit Sinha , Abdul N Malmi-Kakkada , Xin Li , Himadri S. Samanta , D. Thirumalai

Diffuse low grade gliomas are slowly growing tumors that always recur after treatment. In this paper, we revisit the modeling of the tumor radius evolution before and after the radiotherapy process and propose a novel model that is simple,…

Medical Physics · Physics 2021-07-07 Leo Adenis , Stephane Plaszczynski , Basile Grammaticos , Johan Pallud , Mathilde Badoual

Glioblastoma multiforme (GBM), the most aggressive primary brain tumour, exhibits low survival rates due to its rapid growth, infiltrates surrounding brain tissue, and is highly resistant to treatment. One major challenge is oedema…

The most common primary brain tumors are gliomas, evolving from the cerebral supportive cells. For clinical follow-up, the evaluation of the preoperative tumor volume is essential. Volumetric assessment of tumor volume with manual…

Computer Vision and Pattern Recognition · Computer Science 2011-03-11 Jan Egger , Dženan Zukić , Miriam H. A. Bauer , Daniela Kuhnt , Barbara Carl , Bernd Freisleben , Andreas Kolb , Christopher Nimsky

Glioma is one of the most common and aggressive types of primary brain tumors. The accurate segmentation of subcortical brain structures is crucial to the study of gliomas in that it helps the monitoring of the progression of gliomas and…

Image and Video Processing · Electrical Eng. & Systems 2018-03-02 Lele Chen , Yue Wu , Adora M. DSouza , Anas Z. Abidin , Axel Wismuller , Chenliang Xu

Glioblastoma is the most malignant type of central nervous system tumor with GBM subtypes cleaved based on molecular level gene alterations. These alterations are also happened to affect the histology. Thus, it can cause visible changes in…

Quantitative Methods · Quantitative Biology 2020-10-28 Navodini Wijethilake , Mobarakol Islam , Dulani Meedeniya , Charith Chitraranjan , Indika Perera , Hongliang Ren

The concept of tumor field effect implies that cancer is a systemic disease with its impact way beyond the visible tumor confines. For instance, in Glioblastoma (GBM), an aggressive brain tumor, the increase in intracranial pressure due to…

Grade II gliomas are slowly growing primary brain tumors that affect mostly young patients and become fatal after a few years. Current clinical handling includes surgery as first line treatment. Cytotoxic therapies (radiotherapy RT or…

Quantitative Methods · Quantitative Biology 2014-07-09 Victor M. Perez-Garcia

Glioblastoma are known to infiltrate the brain parenchyma instead of forming a solid tumor mass with a defined boundary. Only the part of the tumor with high tumor cell density can be localized through imaging directly. In contrast, brain…

Gliomas are brain tumors composed of different highly heterogeneous histological subregions. Image analysis techniques to identify relevant tumor substructures have high potential for improving patient diagnosis, treatment and prognosis.…

Image and Video Processing · Electrical Eng. & Systems 2022-07-18 José Gerardo Suárez-García Javier Miguel Hernández-López , Eduardo Moreno-Barbosa , Benito de Celis-Alonso

Automatic segmentation is essential for the brain tumor diagnosis, disease prognosis, and follow-up therapy of patients with gliomas. Still, accurate detection of gliomas and their sub-regions in multimodal MRI is very challenging due to…

Image and Video Processing · Electrical Eng. & Systems 2022-12-20 Ramy A. Zeineldin , Mohamed E. Karar , Oliver Burgert , Franziska Mathis-Ullrich

Gliomas are the most prevalent type of primary brain tumors, and their accurate segmentation from MRI is critical for diagnosis, treatment planning, and longitudinal monitoring. However, the scarcity of high-quality annotated imaging data…

Glioma, the prevalent primary brain tumor, exhibits diverse aggressiveness levels and prognoses. Precise classification of glioma is paramount for treatment planning and predicting prognosis. This study aims to develop an algorithm to fuse…

Image and Video Processing · Electrical Eng. & Systems 2026-03-10 Kiranmayee Janardhan , Christy Bobby Thomas

In this study, Brillouin spectroscopy was employed to investigate the viscoelastic properties of melanoma cells in vitro. Using a custom-built confocal Brillouin microspectrometer, we obtained Brillouin shifts and full width at half maximum…

Precise molecular subtyping of gliomas, including isocitrate dehydrogenase (IDH) mutation and 1p/19q codeletion, directly guides surgical and therapeutic decisions, yet currently relies on invasive tissue sampling. Deep learning on…

Computer Vision and Pattern Recognition · Computer Science 2026-05-11 Han Jang , Junhyeok Lee , Heeseong Eum , Joon Jang , Yoseob Han , Seung Hong Choi , Kyu Sung Choi

Recent analysis identified distinct genomic subtypes of lower-grade glioma tumors which are associated with shape features. In this study, we propose a fully automatic way to quantify tumor imaging characteristics using deep learning-based…

Image and Video Processing · Electrical Eng. & Systems 2019-06-11 Mateusz Buda , Ashirbani Saha , Maciej A Mazurowski

This paper investigates the correlation between magnetic resonance spectroscopic imaging (MRSI) and magnetic resonance fingerprinting (MRF) in glioma patients by comparing neuro-oncological markers obtained from MRSI to T1/T2 maps from MRF.…

We present cytometric classification of live healthy and cancer cells by using the spatial morphological and textural information found in the label-free quantitative phase images of the cells. We compare both healthy cells to primary tumor…

Quantitative Methods · Quantitative Biology 2020-01-23 Darina Roitshtain , Lauren Wolbromsky , Evgeny Bal , Hayit Greenspan , Lisa L. Satterwhite , Natan T. Shaked

Diffuse gliomas are malignant brain tumors that grow widespread through the brain. The complex interactions between neoplastic cells and normal tissue, as well as the treatment-induced changes often encountered, make glioma tumor growth…

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