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The propulsion of mammalian spermatozoa relies on the spontaneous periodic oscillation of their flagella. These oscillations are driven internally by the coordinated action of ATP-powered dynein motors that exert sliding forces between…

Fluid Dynamics · Physics 2022-10-13 Chenji Li , Brato Chakrabarti , Pedro Castilla , Achal Mahajan , David Saintillan

Turbulence plays a major role in shaping marine community structure as it affects organism dispersal and guides fundamental ecological interactions. Below oceanographic mesoscale dynamics, turbulence also impinges on subtle…

Biological Physics · Physics 2019-10-29 Matteo Borgnino , Jorge Arrieta , Guido Boffetta , Filippo De Lillo , Idan Tuval

Eukaryotic swimming cells such as spermatozoa, algae or protozoa use flagella or cilia to move in viscous fluids. The motion of their flexible appendages in the surrounding fluid induces propulsive forces that balance with the viscous drag…

Soft Condensed Matter · Physics 2023-10-06 Maciej Lisicki , Marcos F. Velho Rodrigues , Eric Lauga

Topological defects are increasingly being identified in various biological systems, where their characteristic flow fields and stress patterns are associated with continuous active stress generation by biological entities. Here, using…

Soft Condensed Matter · Physics 2022-11-09 Lasse Bonn , Aleksandra Ardaseva , Romain Mueller , Tyler N. Shendruk , Amin Doostmohammadi

Swimming eukaryotic microorganisms such as spermatozoa, algae and ciliates self-propel in viscous fluids using travelling wave-like deformations of slender appendages called flagella. Waves are predominant because Purcell's scallop theorem…

Fluid Dynamics · Physics 2020-11-18 Eric Lauga

Many cells exploit the bending or rotation of flagellar filaments in order to self-propel in viscous fluids. While appropriate theoretical modelling is available to capture flagella locomotion in simple, Newtonian fluids, formidable…

Biological Physics · Physics 2017-08-02 Emily E. Riley , Eric Lauga

Gene regulatory dynamics is governed by molecular processes and therefore exhibits an inherent stochasticity. However, for the survival of an organism it is a strict necessity that this intrinsic noise does not prevent robust functioning of…

Molecular Networks · Quantitative Biology 2007-05-23 Stefan Braunewell , Stefan Bornholdt

The bending of cilia and flagella is driven by forces generated by dynein motor proteins. These forces slide adjacent microtubule doublets within the axoneme, the motile cytoskeletal structure. To create regular, oscilla- tory beating…

Biological Physics · Physics 2015-06-19 V. Mukundan , P. Sartori , V. F. Geyer , F. Julicher , J. Howard

To mimic the mechanical response of passive biological cilia in complex fluids, we study the bending dynamics of an anchored elastic fiber submitted to a dilute granular suspension under shear. We show that the bending fluctuations of the…

Left-right axis specification establishes embryonic laterality through asymmetric signaling cascades originating at the cellular scale. We previously reported the presence of a directionality bias in confined pairs of endothelial (and…

Cell Behavior · Quantitative Biology 2026-03-31 Egun Im , Ghina Badih , Laetitia Kurzawa , Andreas Buttenschön , Calina Copos

Many swimming bacteria are propelled by flagellar motors that stochastically switch between the clockwise and counterclockwise rotation direction. While the switching dynamics are one of the most important characteristics of flagellar…

Subcellular Processes · Quantitative Biology 2008-11-18 Siebe B. van Albada , Sorin Tanase-Nicola , Pieter Rein ten Wolde

Geometric confinement plays an important role in the dynamics of natural and synthetic microswimmers from bacterial cells to self-propelled particles in high-throughput microfluidic devices. However, little is known about the effects of…

Fluid Dynamics · Physics 2014-11-13 Alan Cheng Hou Tsang , Eva Kanso

Ciliary oscillations driven by molecular motors cause fluid motion at micron scale. Stable oscillations require a substantial source of dissipation to balance the energy input of motors. Conventionally, it stems from external fluid. We…

Soft Condensed Matter · Physics 2021-02-23 Debasmita Mondal , Ronojoy Adhikari , Prerna Sharma

Sustained rhythmic oscillations, pulsing dynamics, emerge spontaneously when the local connection scheme is randomised in 3-value cellular automata that feature"glider" dynamics. Time-plots of pulsing measures maintain a distinct waveform…

Cellular Automata and Lattice Gases · Physics 2021-03-02 Andrew Wuensche , Edward Coxon

We develop a framework for the general interpretation of the stochastic dynamical system near a limit cycle. Such quasi-periodic dynamics are commonly found in a variety of nonequilibrium systems, including the spontaneous oscillations of…

Statistical Mechanics · Physics 2018-10-30 Janaki Sheth , Dolores Bozovic , Alex Levine

The motility of cilia and flagella is driven by thousands of dynein motors that hydrolyze adenosine triphosphate (ATP). Despite decades of genetic, biochemical, structural and biophysical studies, some aspects of ciliary motility remain…

Biological Physics · Physics 2015-12-22 Daniel T. N. Chen , Michael Heymann , Seth Fraden , Daniela Nicastro , Zvonimir Dogic

We present a simplified theory for semiflexible flagella under the action of a traveling-wave perturbation that emulates the organized active forces generated by molecular motors, capable of inducing beating patterns to the filament. By…

Soft Condensed Matter · Physics 2025-07-16 Fabio Cecconi , Dario Lucente , Andrea Puglisi , Massimiliano Viale

In the past decade the volvocine green algae, spanning from the unicellular $Chlamydomonas$ to multicellular $Volvox$, have emerged as model organisms for a number of problems in biological fluid dynamics. These include flagellar…

Soft Condensed Matter · Physics 2014-09-22 Raymond E. Goldstein

Pancreatic beta cells are coupled excitable oscillators that synchronize their activity via different communication pathways. Their oscillatory activity manifests itself on multiple timescales and consists of bursting electrical activity,…

Biological Physics · Physics 2023-09-14 Marko Šterk , Uroš Barać , Andraž Stožer , Marko Gosak

Since the earliest electroencephalography experiments, large scale oscillations have been observed in the mammalian brain. More recently, episodes of oscillation and bursting have been identified not only in the cerebral cortex and…

Neurons and Cognition · Quantitative Biology 2025-09-03 Daniel Pouzzner
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