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Handheld Optical Coherence Tomography Angiography (OCTA) enables noninvasive retinal imaging in uncooperative or pediatric subjects, but is highly susceptible to motion artifacts that severely degrade volumetric image quality. Sudden motion…

Computer Vision and Pattern Recognition · Computer Science 2026-02-03 Nick DiSanto , Ehsan Khodapanah Aghdam , Han Liu , Jacob Watson , Yuankai K. Tao , Hao Li , Ipek Oguz

The area of the foveal avascular zone (FAZ) from en face images of optical coherence tomography angiography (OCTA) is one of the most common measurement based on this technology. However, its use in clinic is limited by the high variation…

Image and Video Processing · Electrical Eng. & Systems 2021-12-07 Giovanni Ometto , Giovanni Montesano , Usha Chakravarthy , Frank Kee , Ruth E. Hogg , David P. Crabb

Optical coherence tomography (OCT) is a non-invasive volumetric imaging modality with high spatial and temporal resolution. For imaging larger tissue structures, OCT probes need to be moved to scan the respective area. For handheld…

Computer Vision and Pattern Recognition · Computer Science 2026-03-24 Suresh Guttikonda , Maximilian Neidhardt , Vidas Raudonis , Alexander Schlaefer

Optical Coherence Tomography (OCT) imaging plays an important role in glaucoma diagnosis in clinical practice. Early detection and timely treatment can prevent glaucoma patients from permanent vision loss. However, only a dearth of…

Computer Vision and Pattern Recognition · Computer Science 2019-07-31 Xi Wang , Hao Chen , Luyang Luo , An-ran Ran , Poemen P. Chan , Clement C. Tham , Carol Y. Cheung , Pheng-Ann Heng

Optical Coherence Tomography (OCT) is a widely used non-invasive biomedical imaging modality that can rapidly provide volumetric images of samples. Here, we present a deep learning-based image reconstruction framework that can generate…

Image and Video Processing · Electrical Eng. & Systems 2021-07-30 Yijie Zhang , Tairan Liu , Manmohan Singh , Yilin Luo , Yair Rivenson , Kirill V. Larin , Aydogan Ozcan

Computational corrections of defocus and aberrations in optical coherence tomography (OCT) offers a promising approach to realize high-resolution imaging with deep imaging depth, but without additional high hardware costs. However, these…

Optics · Physics 2025-10-28 Shuichi Makita , Naoki Fukutake , Lida Zhu , Yoshiaki Yasuno

Our objective is to evaluate the efficacy of methods that use deep learning (DL) for the automatic fine-grained segmentation of optical coherence tomography (OCT) images of the retina. OCT images from 10 patients with mild non-proliferative…

Computer Vision and Pattern Recognition · Computer Science 2018-01-31 Mike Pekala , Neil Joshi , David E. Freund , Neil M. Bressler , Delia Cabrera DeBuc , Philippe M Burlina

Diabetic Retinopathy (DR) caused by diabetes occurs as a result of changes in the retinal vessels and causes visual impairment. Microaneurysms (MAs) are the early clinical signs of DR, whose timely diagnosis can help detecting DR in the…

Image and Video Processing · Electrical Eng. & Systems 2022-05-11 Elahe Sadat Kazemi Nasab , Ramin Almasi , Bijan Shoushtarian , Ehsan Golkar , Hossein Rabbani

In this work, we propose an advanced AI based grading system for OCT images. The proposed system is a very deep fully convolutional attentive classification network trained with end to end advanced transfer learning with online random…

Computer Vision and Pattern Recognition · Computer Science 2018-12-19 Mrinal Haloi

Segmenting specific targets or biomarkers is necessary to analyze optical coherence tomography angiography (OCTA) images. Previous methods typically segment all the targets in an OCTA sample, such as retinal vessels (RVs). Although these…

Machine Learning · Computer Science 2024-03-21 Xinrun Chen , Chengliang Wang , Haojian Ning , Shiying Li , Mei Shen

Purpose: To develop a deep learning approach to digitally-stain optical coherence tomography (OCT) images of the optic nerve head (ONH). Methods: A horizontal B-scan was acquired through the center of the ONH using OCT (Spectralis) for 1…

Optical coherence tomography (OCT) is widely used for diagnosing and monitoring retinal diseases, such as age-related macular degeneration (AMD). The segmentation of biomarkers such as layers and lesions is essential for patient diagnosis…

Computer Vision and Pattern Recognition · Computer Science 2025-09-26 Botond Fazekas , Guilherme Aresta , Philipp Seeböck , Julia Mai , Ursula Schmidt-Erfurth , Hrvoje Bogunović

Alterations in retinal layer thickness, measurable using Optical Coherence Tomography (OCT), have been associated with neurodegenerative diseases such as Alzheimer's disease (AD). While previous studies have mainly focused on segmented…

Computer Vision and Pattern Recognition · Computer Science 2025-11-10 Yasemin Turkan , F. Boray Tek , M. Serdar Nazlı , Öykü Eren

In this chapter a general mathematical model of Optical Coherence Tomography (OCT) is presented on the basis of the electromagnetic theory. OCT produces high resolution images of the inner structure of biological tissues. Images are…

Numerical Analysis · Mathematics 2016-04-19 Peter Elbau , Leonidas Mindrinos , Otmar Scherzer

Optical coherence tomography (OCT) has seen widespread success as an in vivo clinical diagnostic 3D imaging modality, impacting areas including ophthalmology, cardiology, and gastroenterology. Despite its many advantages, such as high…

Optical Coherence Tomography (OCT) was originally conceived as a volumetric imaging method. Quickly, OCT images went beyond structural data and started to provide functional information about an object enabling for example visualization of…

In this paper, we propose the use of Optical Coherence Tomography (OCT) imaging for the problem of iris presentation attack (PA) detection. We assess its viability by comparing its performance with respect to traditional iris imaging…

Computer Vision and Pattern Recognition · Computer Science 2020-11-24 Renu Sharma , Arun Ross

The aortic vessel tree is composed of the aorta and its branching arteries, and plays a key role in supplying the whole body with blood. Aortic diseases, like aneurysms or dissections, can lead to an aortic rupture, whose treatment with…

Image and Video Processing · Electrical Eng. & Systems 2023-04-04 Yuan Jin , Antonio Pepe , Jianning Li , Christina Gsaxner , Fen-hua Zhao , Kelsey L. Pomykala , Jens Kleesiek , Alejandro F. Frangi , Jan Egger

Automatic retinal layer segmentation with medical images, such as optical coherence tomography (OCT) images, serves as an important tool for diagnosing ophthalmic diseases. However, it is challenging to achieve accurate segmentation due to…

Image and Video Processing · Electrical Eng. & Systems 2024-04-26 Xiang He , Weiye Song , Yiming Wang , Fabio Poiesi , Ji Yi , Manishi Desai , Quanqing Xu , Kongzheng Yang , Yi Wan

This study is to characterize reflectance profiles of retinal blood vessels in optical coherence tomography (OCT), and to validate these vascular features to guide artery-vein classification in OCT angiography (OCTA) of human retina.…

Tissues and Organs · Quantitative Biology 2022-02-08 Tobiloba Adejumo , Tae-Hoon Kim , David Le , Taeyoon Son , Guangying Ma , Xincheng Yao