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Comparative binary outcome data are of fundamental interest in statistics and are often pooled in meta-analyses. Here we examine the simplest case where for each study there are two patient groups and a binary event of interest, giving rise…

Methodology · Statistics 2018-06-12 Rose Baker , Dan Jackson

In mediation analysis, the effect of an exposure (or treatment) on an outcome variable is decomposed into two components: a direct effect, which pertains to an immediate influence of the exposure on the outcome, and an indirect effect,…

Methodology · Statistics 2017-10-04 Marco Geraci , Alessandra Mattei

Laboratory experiments have shown that cardiovascular diseases are positively correlated to the concentration of ambient air pollutants, such as SO2, NO2, PM10, etc. It has also been repeatedly reported in many countries that increased…

Applications · Statistics 2013-08-08 Menghui Li , Dasheng Luo , Chenghua Cao , Xiaochuan Pan , Qixin Wang

Nowadays air pollution becomes one of the biggest world issues in both developing and developed countries. Helping individuals understand their air pollution exposure and health risks, the traditional way is to utilize data from static…

Computers and Society · Computer Science 2020-05-29 Ke Hu , Ashfaqur Rahman , Hassan Habibi Gharakheili , Vijay Sivaraman

Unobserved confounding is one of the main challenges when estimating causal effects. We propose a causal reduction method that, given a causal model, replaces an arbitrary number of possibly high-dimensional latent confounders with a single…

Machine Learning · Statistics 2023-02-24 Maximilian Ilse , Patrick Forré , Max Welling , Joris M. Mooij

Many studies have proposed a relationship between COVID-19 transmissibility and ambient pollution levels. However, a major limitation in establishing such associations is to adequately account for complex disease dynamics, influenced by…

Populations and Evolution · Quantitative Biology 2021-09-07 Ognjen Milicevic , Igor Salom , Andjela Rodic , Sofija Markovic , Marko Tumbas , Dusan Zigic , Magdalena Djordjevic , Marko Djordjevic

This paper explores the topic of preferential sampling, specifically situations where monitoring sites in environmental networks are preferentially located by the designers. This means the data arising from such networks may not accurately…

Applications · Statistics 2014-12-04 James V. Zidek , Gavin Shaddick , Carolyn G. Taylor

Pollutant exposure during gestation is a known and adverse factor for birth and health outcomes. However, the links between prenatal air pollution exposures and educational outcomes are less clear, in particular the critical windows of…

Methodology · Statistics 2022-10-11 Yunan Gao , Daniel R. Kowal

Random disturbances such as air pollution may affect cognitive performance, which, particularly in high-stakes settings, may have severe consequences for an individual's productivity and well-being. This paper examines the short-term…

General Economics · Economics 2025-06-25 Agata Galkiewicz

Knowledge of the severity of an influenza outbreak is crucial for informing and monitoring appropriate public health responses, both during and after an epidemic. However, case-fatality, case-intensive care admission and…

Observational cohort studies with oversampled exposed subjects are typically implemented to understand the causal effect of a rare exposure. Because the distribution of exposed subjects in the sample differs from the source population,…

Methodology · Statistics 2019-02-14 Sherri Rose

Air pollution, especially the particulate matter 2.5 (PM2.5), has become a growing concern in recent years, primarily in urban areas. Being exposed to air pollution is linked to developing numerous health problems, like the aggravation of…

Machine Learning · Computer Science 2025-11-04 Dragoş-Andrei Şerban , Răzvan-Alexandru Smădu , Dumitru-Clementin Cercel

Small area ecological studies are commonly used in epidemiology to assess the impact of area level risk factors on health outcomes when data are only available in an aggregated form. However the resulting estimates are often biased due to…

Applications · Statistics 2017-01-19 Yingbo Wang , Sylvia Richardson , Anna Hansell , Marta Blangiardo

Establishing cause-effect relationships from observational data often relies on untestable assumptions. It is crucial to know whether, and to what extent, the conclusions drawn from non-experimental studies are robust to potential…

Real-time air pollution monitoring is a valuable tool for public health and environmental surveillance. In recent years, there has been a dramatic increase in air pollution forecasting and monitoring research using artificial neural…

Machine Learning · Computer Science 2022-11-11 Chen Lin , Safoora Yousefi , Elvis Kahoro , Payam Karisani , Donghai Liang , Jeremy Sarnat , Eugene Agichtein

Modified treatment policies are a widely applicable class of interventions useful for studying the causal effects of continuous exposures. Approaches to evaluating their causal effects assume no interference, meaning that such effects…

Methodology · Statistics 2025-12-12 Salvador V. Balkus , Scott W. Delaney , Nima S. Hejazi

Alcohol misuse is a key target of public health strategies aimed at reducing cardiovascular risk. The effect of excessive alcohol consumption on blood pressure may vary systematically with individuals' unobserved propensity to engage in…

Methodology · Statistics 2026-03-11 Ashish Patel , Francis J DiTraglia , Stephen Burgess

Difference-in-differences (DID) is a popular approach to identify the causal effects of treatments and policies in the presence of unmeasured confounding. DID identifies the sample average treatment effect in the treated (SATT). However, a…

Methodology · Statistics 2024-06-21 Audrey Renson , Ellicott C. Matthay , Kara E. Rudolph

Estimating health benefits of reducing fossil fuel use from improved air quality provides important rationales for carbon emissions abatement. Simulating pollution concentration is a crucial step of the estimation, but traditional…

General Economics · Economics 2021-06-01 Da Zhang , Qingyi Wang , Shaojie Song , Simiao Chen , Mingwei Li , Lu Shen , Siqi Zheng , Bofeng Cai , Shenhao Wang

Air pollution (e.g., PM2.5) has a negative effect on human health. Recently, the population-weighted annual mean PM2.5 concentration (PWAM) has been selected as an indicator 11.6.2 in Sustainable Development Goals (SDGs), for various…

Computers and Society · Computer Science 2022-08-31 Yuheng Zhang , Qi Zhou , Ke Chang