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Accurately assessing the postmortem interval (PMI) is an important task in forensic science. Some of the existing techniques use regression models that use a decomposition score to predict the PMI or accumulated degree days (ADD), however,…

Machine Learning · Computer Science 2024-09-17 Anna-Maria Nau , Phillip Ditto , Dawnie Wolfe Steadman , Audris Mockus

The last two decades have seen intense scientific and regulatory interest in the health effects of particulate matter (PM). Influential epidemiological studies that characterize chronic exposure of individuals rely on monitoring data that…

Applications · Statistics 2009-06-09 Christopher J. Paciorek , Jeff D. Yanosky , Robin C. Puett , Francine Laden , Helen H. Suh

There is an increasing interest in estimating heterogeneity in causal effects in randomized and observational studies. However, little research has been conducted to understand heterogeneity in an instrumental variables study. In this work,…

Methodology · Statistics 2021-01-20 Michael Johnson , Jiongyi Cao , Hyunseung Kang

Suppose, contrary to fact, in 1950, we had put the cohort of 18 year old non-smoking American men on a stringent mandatory diet that guaranteed that no one would ever weigh more than their baseline weight established at age 18. How would…

Applications · Statistics 2008-02-06 James Robins

Interference occurs when a unit's treatment (or exposure) affects another unit's outcome. In some settings, units may be grouped into clusters such that it is reasonable to assume that interference, if present, only occurs between…

Methodology · Statistics 2023-08-24 Chanhwa Lee , Donglin Zeng , Michael G. Hudgens

Air pollution is a major global environmental health threat, in particular for people who live or work near pollution sources. Areas adjacent to pollution sources often have high ambient pollution concentrations, and those areas are…

Machine Learning · Computer Science 2022-11-16 Yawen Zhang , Michael Hannigan , Qin Lv

Air pollution, particularly particulate matter (PM2.5), poses significant risks to public health and the environment, necessitating accurate prediction and continuous monitoring for effective air quality management. However, air quality…

Machine Learning · Computer Science 2024-09-19 Yohan Choi , Boaz Choi , Jachin Choi

Investigators often use multi-source data (e.g., multi-center trials, meta-analyses of randomized trials, pooled analyses of observational cohorts) to learn about the effects of interventions in subgroups of some well-defined target…

Methodology · Statistics 2024-02-06 Guanbo Wang , Alexander Levis , Jon Steingrimsson , Issa Dahabreh

We consider the problem in precision health of grouping people into subpopulations based on their degree of vulnerability to a risk factor. These subpopulations cannot be discovered with traditional clustering techniques because their…

Machine Learning · Statistics 2018-12-11 Alexander New , Kristin P. Bennett

Sensitivity analysis is widely used to assess the robustness of causal conclusions in observational studies, yet its interaction with the structure of measured covariates is often overlooked. When latent confounders cannot be directly…

Methodology · Statistics 2026-02-17 Abhinandan Dalal , Iris Horng , Yang Feng , Dylan S. Small

Given that hierarchical count data in many fields are not Normally-distributed and include random effects, this paper extends the Generalized Linear Mixed Models (GLMMs) into Poisson Mixed-Effect Linear Model (PMELM) and do numerical…

Methodology · Statistics 2018-05-09 N. Zhang

Several key metrics in public health convey the probability that a primary event will lead to a more serious secondary event in the future. These "severity rates" can change over the course of an epidemic in response to shifting conditions…

Two-stage randomized experiments are becoming an increasingly popular experimental design for causal inference when the outcome of one unit may be affected by the treatment assignments of other units in the same cluster. In this paper, we…

Methodology · Statistics 2022-10-21 Zhichao Jiang , Kosuke Imai , Anup Malani

Data collection in economically constrained countries often necessitates using approximate and biased measurements due to the low-cost of the sensors used. This leads to potentially invalid predictions and poor policies or decision making.…

Machine Learning · Computer Science 2019-12-02 Michael T. Smith , Joel Ssematimba , Mauricio A. Alvarez , Engineer Bainomugisha

Matching is a widely used causal inference design that aims to approximate a randomized experiment using observational data by forming matched sets of treated and control units based on similarities in their covariates. Ideally, treated…

Methodology · Statistics 2026-04-06 Jianan Zhu , Jeffrey Zhang , Zijian Guo , Siyu Heng

With medical tests becoming increasingly available, concerns about over-testing and over-treatment dramatically increase. Hence, it is important to understand the influence of testing on treatment selection in general practice. Most…

Methodology · Statistics 2020-08-11 Yun Li , Irina Bondarenko , Michael R. Elliott , Timothy P. Hofer , Jeremy M. G. Taylor

The causal link between victimization and violence later in life is largely accepted but has been understudied for victimized adolescents. In this work we use the Add Health dataset, the largest nationally representative longitudinal survey…

Methodology · Statistics 2023-09-25 Mateo Dulce Rubio , Edward H. Kennedy , Valerio Baćak , Daniel S. Nagin

For atoms embedded in dense plasma, the plasma screening effects will greatly alter their structure and dynamics, and then determine the radiation transport properties of the plasma. In the present work, a new statistical model is proposed…

Plasma Physics · Physics 2020-11-25 Fuyang Zhou , Yizhi Qu , Junwen Gao , Yulong Ma , Yong Wu , Jianguo Wang

Tests for paired censored outcomes have been extensively studied, with some justified in the context of randomization-based inference. These tests are primarily designed to detect an overall treatment effect across the entire follow-up…

Methodology · Statistics 2025-06-10 Sangjin Lee , Kwonsang Lee

Increasingly, medical research is dependent on data collected for non-research purposes, such as electronic health records data (EHR). EHR data and other large databases can be prone to measurement error in key exposures, and unadjusted…

Methodology · Statistics 2020-05-13 Kyunghee Han , Thomas Lumley , Bryan E. Shepherd , Pamela A. Shaw
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