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Epidemic models are a valuable tool in the decision making process. Once a mathematical model for an epidemics has been established, the very next step is calculating a mathematical expression for the basic reproductive number, $R_0$, which…

Populations and Evolution · Quantitative Biology 2022-09-07 Carlos Hernandez-Suarez , Osval Montesinos Lopez

When controlling an emerging outbreak of an infectious disease it is essential to know the key epidemiological parameters, such as the basic reproduction number $R_0$ and the control effort required to prevent a large outbreak. These…

Populations and Evolution · Quantitative Biology 2016-04-18 Pieter Trapman , Frank Ball , Jean-Stéphane Dhersin , Viet Chi Tran , Jacco Wallinga , Tom Britton

A pulse vaccination SIR model with periodic infection rate $\beta (t)$ have been proposed and studied. The basic reproductive number $R_0$ is defined. The dynamical behaviors of the model are analyzed with the help of persistence,…

Chaotic Dynamics · Physics 2009-05-29 Zhen Jin , Mainul Haque , Quanxing Liu

An SIR epidemic model with free boundary is investigated. This model describes the transmission of diseases. The behavior of positive solutions to a reaction-diffusion system in a radially symmetric domain is investigated. The existence and…

Analysis of PDEs · Mathematics 2013-02-05 Kwang Ik Kim , Zhigui Lin , Qunying Zhang

In order to explore the impact of periodically evolving domain on the transmission of disease, we study a SIS reaction-diffusion model with logistic term on a periodically evolving domain. The basic reproduction number ${\mathcal{R}}_0$ is…

Analysis of PDEs · Mathematics 2020-11-17 Yachun Tong , Zhigui Lin

Studies about epidemic modelling have been conducted since before 19th century. Both deterministic and stochastiic model were used to capture the dynamic of infection in the population. The purpose of this project is to investigate the…

Populations and Evolution · Quantitative Biology 2018-03-06 Kurnia Susvitasari

In the framework of population dynamics, the basic reproduction number R_0 is, by definition, the expected number of offspring that an individual has during its lifetime. In constant and time periodic environments it is calculated as the…

Analysis of PDEs · Mathematics 2026-04-16 Carles Barril , Àngel Calsina , Sílvia Cuadrado , Jordi Ripoll

In this paper, we consider a compartmental SIRS epidemic model with asymptomatic infection and seasonal succession, which is a periodic discontinuous differential system. The basic reproduction number $\mathcal{R}_0$ is defined and valuated…

Dynamical Systems · Mathematics 2017-08-15 Yilei Tang , Dongmei Xiao , Weinian Zhang , Di Zhu

The basic reproductive number -- $R_0$ -- is one of the most common and most commonly misapplied numbers in public health. Although often used to compare outbreaks and forecast pandemic risk, this single number belies the complexity that…

Populations and Evolution · Quantitative Biology 2020-04-15 Laurent Hébert-Dufresne , Benjamin M. Althouse , Samuel V. Scarpino , Antoine Allard

The basic reproduction number ($R_0$) is a threshold parameter for disease extinction or survival in isolated populations. However no human population is fully isolated from other human or animal populations. We use compartmental models to…

Populations and Evolution · Quantitative Biology 2018-09-05 Angus McLure , Kathryn Glass

The reproduction number of deterministic models is an essential quantity to predict whether an epidemic will spread or die out. Thresholds for disease extinction contribute crucial knowledge on disease control, elimination, and mitigation…

Populations and Evolution · Quantitative Biology 2013-08-08 Ling Xue , Caterina Scoglio

The basic reproduction ratio is a crucial threshold parameter in infectious disease models. In nonlocal dispersal systems, its variational characterization is challenging due to the possible absence of a principal eigenvalue caused by…

Analysis of PDEs · Mathematics 2026-05-27 Xiandong Lin , Jiazhuo Cheng , Qiru Wang

A social (sexual) network is modeled by an extension of the configuration model to the situation where edges have weights, e.g. reflecting the number of sex-contacts between the individuals. An epidemic model is defined on the network such…

Probability · Mathematics 2011-12-21 Tom Britton , David Lindenstrand

The basic reproduction number, $R_0$, is a well-known quantifier of epidemic spread. However, a class of existing methods for estimating $R_0$ from incidence data early in the epidemic can lead to an over-estimation of this quantity. In…

Populations and Evolution · Quantitative Biology 2024-03-27 Wajid Ali , Christopher E. Overton , Robert R. Wilkinson , Kieran J. Sharkey

A key parameter in models for the spread of infectious diseases is the basic reproduction number $R_0$, which is the expected number of secondary cases a typical infected primary case infects during its infectious period in a large mostly…

Populations and Evolution · Quantitative Biology 2017-09-05 Kristoffer Spricer , Pieter Trapman

A current challenge for disease modeling and public health is understanding pathogen dynamics across scales since their ecology and evolution ultimately operate on several coupled scales. This is particularly true for vector-borne diseases,…

Populations and Evolution · Quantitative Biology 2019-12-19 Hayriye Gulbudak

We consider a stochastic model of infection spread on the complete graph on $N$ vertices incorporating dynamic partnerships, which we assume to be monogamous. This can be seen as a variation on the contact process in which some form of edge…

Probability · Mathematics 2016-06-23 Eric Foxall , Roderick Edwards , P. van den Driessche

A multi-patch and multi-group modeling framework describing the dynamics of a class of diseases driven by the interactions between vectors and hosts structured by groups is formulated. Hosts' dispersal is modeled in terms of patch-residence…

Populations and Evolution · Quantitative Biology 2017-03-16 Derdei Bichara , Carlos Castillo-Chavez

When an infectious disease strikes a population, the number of newly reported cases is often the only available information that one can obtain during early stages of the outbreak. An important goal of early outbreak analysis is to obtain a…

Quantitative Methods · Quantitative Biology 2013-05-30 Bahman Davoudi , Babak Pourbohloul , Joel Miller , Rafael Meza , Lauren Ancel Meyers , David J. D. Earn

In this paper we first introduce the general stochastic epidemic model for the spread of infectious diseases. Then we give methods for inferring model parameters such as the basic reproduction number $R_0$ and vaccination coverage $v_c$…

Methodology · Statistics 2014-11-14 Tom Britton , Federica Giardina