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Hair cells, the sensory receptors of the internal ear, subserve different functions in various receptor organs: they detect oscillatory stimuli in the auditory system, but transduce constant and step stimuli in the vestibular and…
Alzheimer's disease (AD) is a prominent, worldwide, age-related neurodegenerative disease that currently has no systemic treatment. Strong evidence suggests that permeable amyloid-beta peptide (Abeta) oligomers, astrogliosis and reactive…
Rafts, or functional domains, are transient nano- or mesoscopic structures in the plasma membrane and are thought to be essential for many cellular processes such as signal transduction, adhesion, trafficking and lipid/protein sorting.…
A volume coil with squared slots-end ring was developed to attain improved sensitivity for imaging of rat's brain at 7 T. The principles of the high cavity resonator for the low-pass case and the law of Biot-Savart were used to derive a…
Prion is a misfolded protein found in mammals that causes infectious diseases of the nervous system in humans and animals. Prion diseases are invariably fatal and highly infectious neurodegenerative diseases that affect a wide variety of…
A simplified model of periodic chiral beam-lattices containing local resonators has been formulated to obtain a better understanding of the influence of the chirality and of the dynamic characteristics of the local resonators on the…
A significant association between a polymorphism in the D repeat of the gene encoding asporin and osteoarthritis, the most frequent of articular diseases, has been recently reported. The goal of the present study was to investigate the…
Epicardial adipose tissue (EAT) is known for its pro-inflammatory properties and association with Coronavirus Disease 2019 (COVID-19) severity. However, current EAT segmentation methods do not consider positional information. Additionally,…
We analyze images of a rock on Ryugu acquired in situ by MASCam, camera of the MASCOT lander, with the aim of identifying possible carbonaceous chondrite (CC) analogs. The rock's reflectance ($r_{\rm F} = 0.034 \pm 0.003$ at phase angle…
Adenosine receptors are G-protein-coupled receptors involved in a wide range of physiological and pathological phenomena in most mammalian systems. All four receptors are widely expressed in the central nervous system, where they modulate…
In this paper, we propose a deep learning-based method to segment the skeletal structures in the micro-CT images of Dutch-Belted rabbit fetuses which can assist in the assessment of drug-induced skeletal abnormalities as a required study in…
We present simple parametric equations in terms of Jacobi elliptic functions that provide a realistic model of the shape of human normal erythrocytes as well as of variations in size (anisocytosis) and shape (poikilocytosis) thereof. We…
EGG recordings performed on 13 local white rabbits (O. cuniculus) which divided into 3 groups; acetosal 35 mg/kgBM receiver, reserpine 37.5 mg/kgBM receiver, and control group. A total of 72 EGG recordings obtained from them, which divided…
Osteoarthritis (OA), a chronic disease characterized by articular cartilage degeneration, is a leading cause of disability and pain worldwide. In OA, chondrocytes in cartilage undergo phenotypic changes and senescence, restricting cartilage…
Recent Alzheimer's disease (AD) patient studies have focused on retinal analysis, as the retina is the only part of the central nervous system which can be imaged non-invasively by optical methods. However as this is a relatively new…
The auditory pathway is widely distributed throughout the brain, and is perhaps one of the most interesting networks in the context of neuroplasticity. Accurate mapping of neural activity in the entire pathway, preferably noninvasively, and…
Phagocytosis and receptor-mediated endocytosis are vitally important particle uptake mechanisms in many cell types, ranging from single-cell organisms to immune cells. In both processes, engulfment by the cell depends critically on both…
Structural microvascular alterations and dysfunction serve as key disease indicators of cancer, diabetes, ischemic stroke, neurodegenerative disorders and many other conditions. In vivo visualization of the microvasculature has…
A mathematical model describing the coupling between two independent amplification mechanisms in auditory hair cells is proposed and analyzed. Hair cells are cells in the inner ear responsible for translating sound-induced mechanical…
Epicardial adipose tissue (EAT) is a type of visceral fat that can secrete large amounts of adipokines to affect the myocardium and coronary arteries. EAT volume and density can be used as independent risk markers measurement of volume by…