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Renewal models are widely used in statistical epidemiology as semi-mechanistic models of disease transmission. While primarily used for estimating the instantaneous reproduction number, they can also be used for generating projections,…

Methodology · Statistics 2025-09-25 Nicholas Steyn , Kris V. Parag , Robin N. Thompson , Christl A. Donnelly

Here we treat the transmission of disease through a population as a standard Galton-Watson branching process, modified to take the presence of vaccination into account. Vaccination reduces the number of secondary infections produced per…

Probability · Mathematics 2021-06-15 Arni S. R. Srinivasa Rao , Chris T. Bauch

Vaccination campaigns have both direct and indirect effects that act to control an infectious disease as it spreads through a population. Indirect effects arise when vaccinated individuals block disease transmission in any infection chains…

Populations and Evolution · Quantitative Biology 2024-05-08 Lixin Lin , Homayoun Hamedmoghadam , Robert Shorten , Lewi Stone

In this work, we address a multicoupled dynamics on complex networks with tunable structural segregation. Specifically, we work on a networked epidemic spreading under a vaccination campaign with agents in favor and against the vaccine. Our…

Physics and Society · Physics 2021-09-15 Marcelo A. Pires , Andre L. Oestereich , Nuno Crokidakis , Sílvio M. Duarte Queirós

We consider the simple epidemiological SIS model for a general heterogeneous population introduced by Lajmanovich and Yorke (1976) in finite dimension, and its infinite dimensional generalization we introduced in previous works. In this…

Dynamical Systems · Mathematics 2022-11-29 Jean-François Delmas , Dylan Dronnier , Pierre-André Zitt

As the development of a dengue vaccine is ongoing, we simulate an hypothetical vaccine as an extra protection to the population. In a first phase, the vaccination process is studied as a new compartment in the model, and different ways of…

Optimization and Control · Mathematics 2013-11-26 Helena Sofia Rodrigues , M. Teresa T. Monteiro , Delfim F. M. Torres

We study a dynamics of the epidemiological infection spreading at different values of the risk factor $\beta$ (a control parameter) with the using of dynamic Monte Carlo approach (DMC). In our toy model, the infection transmits due to…

Physics and Society · Physics 2020-06-01 Gennadiy Burlak

The optimal allocation of vaccines to population subgroups over time is a challenging health care management problem. In the context of a pandemic, the interaction between vaccination policies adopted by multiple agents and the cooperation…

Optimization and Control · Mathematics 2021-09-22 David Rey , Ahmed W Hammad , Meead Saberi

Many epidemic models are naturally defined as individual-based models: where we track the state of each individual within a susceptible population. Inference for individual-based models is challenging due to the high-dimensional state-space…

Methodology · Statistics 2025-08-04 Lorenzo Rimella , Christopher Jewell , Paul Fearnhead

In this paper, we address a social planner's optimal control problem for a partially observable stochastic epidemic model. The control measures include social distancing, testing, and vaccination. Using a diffusion approximation for the…

Optimization and Control · Mathematics 2025-03-11 Ibrahim Mbouandi Njiasse , Florent Ouabo Kamkumo , Ralf Wunderlich

We analyze equilibrium behavior and optimal policy within a Susceptible-Infected-Recovered epidemic model augmented with potentially undiagnosed agents who infer their health status and a social planner with imperfect enforcement of social…

Theoretical Economics · Economics 2022-11-01 Thomas Phelan , Alexis Akira Toda

Simulations of infectious disease spread have long been used to understand how epidemics evolve and how to effectively treat them. However, comparatively little attention has been paid to understanding the fairness implications of different…

Social and Information Networks · Computer Science 2019-11-14 James Atwood , Hansa Srinivasan , Yoni Halpern , D Sculley

We consider the problem of distributing a vaccine for immunizing a scale-free network against a given virus or worm. We introduce a new method, based on vaccine dissemination, that seems to reflect more accurately what is expected to occur…

Networking and Internet Architecture · Computer Science 2007-05-23 Alexandre O. Stauffer , Valmir C. Barbosa

A central challenge in every field of biology is to use existing measurements to predict the outcomes of future experiments. In this work, we consider the wealth of antibody inhibition data against variants of the influenza virus. Due to…

Quantitative Methods · Quantitative Biology 2023-07-27 Tal Einav , Rong Ma

We investigate different mean-field-like approximations for stochastic dynamics on graphs, within the framework of a cluster-variational approach. In analogy with its equilibrium counterpart, this approach allows one to give a unified view…

Statistical Mechanics · Physics 2017-07-31 Alessandro Pelizzola , Marco Pretti

When an infectious disease propagates throughout society, the incidence function may rise at first due to an increase in pathogenicity and then decrease due to inhibitory effects until it reaches saturation. Effective vaccination and…

Dynamical Systems · Mathematics 2023-07-11 Sushil Pathak , G. Shirisha , K. Venkata Ratnam

Epidemic spreading can be suppressed by the introduction of containment measures such as social distancing and lock downs. Yet, when such measures are relaxed, new epidemic waves and infection cycles may occur. Here we explore this issue in…

Physics and Society · Physics 2020-12-07 Fabio Caccioli , Daniele De Martino

Compartmental epidemic models are among the most popular ones in epidemiology. For the parameters (e.g., the transmission rate) characterizing these models, the majority of researchers simplify them as constants, while some others manage to…

Machine Learning · Statistics 2020-06-02 Wenjie Zheng

Since the start of the still ongoing COVID-19 pandemic, there have been many modeling efforts to assess several issues of importance to public health. In this work, we review the theory behind some important mathematical models that have…

Populations and Evolution · Quantitative Biology 2022-01-06 Fernando Saldaña , Jorge X Velasco-Hernández

We propose a mathematical model to investigate the effects of information-dependent vaccination behavior on meningitis transmission. The information is represented by means of information index as early proposed in (d'Onofrio et al., Theor.…

Populations and Evolution · Quantitative Biology 2020-05-26 Bruno Buonomo , Alberto d'Onofrio , Semu Mitiku Kassa , Yetwale Hailu Workineh
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