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Previous deep learning approaches for survival analysis have primarily relied on ranking losses to improve discrimination performance, which often comes at the expense of calibration performance. To address such an issue, we propose a novel…

Machine Learning · Computer Science 2024-11-22 Dongjoon Lee , Hyeryn Park , Changhee Lee

Machine learning models that aim to predict dementia onset usually follow the classification methodology ignoring the time until an event happens. This study presents an alternative, using survival analysis within the context of machine…

Machine Learning · Computer Science 2023-06-21 Daniel Stamate , Henry Musto , Olesya Ajnakina , Daniel Stahl

In the era of precision medicine, time-to-event outcomes such as time to death or progression are routinely collected, along with high-throughput covariates. These high-dimensional data defy classical survival regression models, which are…

Methodology · Statistics 2025-07-15 Stephen Salerno , Yi Li

Motion analysis is used in computer vision to understand the behaviour of moving objects in sequences of images. Optimising the interpretation of dynamic biological systems requires accurate and precise motion tracking as well as efficient…

It is standard practice for covariates to enter a parametric model through a single distributional parameter of interest, for example, the scale parameter in many standard survival models. Indeed, the well-known proportional hazards model…

Methodology · Statistics 2020-08-10 Kevin Burke , Gilbert MacKenzie

Traditional survival analysis methods often struggle with complex time-dependent data,failing to capture and interpret dynamic characteristics adequately.This study aims to evaluate the performance of three long-sequence…

Machine Learning · Computer Science 2024-07-22 Runquan Zhang , Jiawen Jiang , Xiaoping Shi

Variational Inference (VI) is a commonly used technique for approximate Bayesian inference and uncertainty estimation in deep learning models, yet it comes at a computational cost, as it doubles the number of trainable parameters to…

Machine Learning · Computer Science 2024-06-25 Christian Marius Lillelund , Martin Magris , Christian Fischer Pedersen

In survival studies it is important to record the values of key longitudinal covariates until the occurrence of event of a subject. For this reason, it is essential to study the association between longitudinal and time-to-event outcomes…

Methodology · Statistics 2021-06-09 Khandoker Akib Mohammad , Yuichi Hirose , Yuan Yao , Budhi Surya

Accurate survival prediction in head and neck cancer (HNC) is essential for guiding clinical decision-making and optimizing treatment strategies. Traditional models, such as Cox proportional hazards, have been widely used but are limited in…

Computer Vision and Pattern Recognition · Computer Science 2024-10-30 Aiman Farooq , Utkarsh Sharma , Deepak Mishra

We propose Lomax delegate racing (LDR) to explicitly model the mechanism of survival under competing risks and to interpret how the covariates accelerate or decelerate the time to event. LDR explains non-monotonic covariate effects by…

Methodology · Statistics 2019-01-03 Quan Zhang , Mingyuan Zhou

The use of massive survival data has become common in survival analysis. In this study, a subsampling algorithm is proposed for the Cox proportional hazards model with time-dependent covariates when the sample is extraordinarily large but…

Computation · Statistics 2023-02-07 Nan Qiao , Wangcheng Li , Feng Xiao , Cunjie Lin , Yong Zhou

Survival prognosis is crucial for medical informatics. Practitioners often confront small-sized clinical data, especially cancer patient cases, which can be insufficient to induce useful patterns for survival predictions. This study deals…

Machine Learning · Computer Science 2025-01-23 Yonghao Zhao , Changtao Li , Chi Shu , Qingbin Wu , Hong Li , Chuan Xu , Tianrui Li , Ziqiang Wang , Zhipeng Luo , Yazhou He

While analysing time-to-event data, it is possible that a certain fraction of subjects will never experience the event of interest and they are said to be cured. When this feature of survival models is taken into account, the models are…

Methodology · Statistics 2020-01-27 Khandoker Akib Mohammad , Yuichi Hirose , Budhi Surya , Yuan Yao

In this manuscript we analyze a data set containing information on children with Hodgkin Lymphoma (HL) enrolled on a clinical trial. Treatments received and survival status were collected together with other covariates such as demographics…

Quantitative Methods · Quantitative Biology 2021-03-29 Cédric Beaulac , Jeffrey S. Rosenthal , Qinglin Pei , Debra Friedman , Suzanne Wolden , David Hodgson

Deep reinforcement learning (DRL) has reached super human levels in complex tasks like game solving (Go and autonomous driving). However, it remains an open question whether DRL can reach human level in applications to financial problems…

Portfolio Management · Quantitative Finance 2020-11-10 Eric Benhamou , David Saltiel , Jean-Jacques Ohana , Jamal Atif

Organizations interact with the environment and with other organizations, and these interactions constitute an important way of learning and evolution. To overcome the problems that they face during their existence, organizations must…

Applications · Statistics 2020-05-05 Paula Lopes , Pedro Campos , Luis Meira-Machado

Survival analysis aims to estimate a time-to-event distribution from data with censored observations. Many existing methods either impose structural assumptions on the hazard function or discretize the time axis, which may limit flexibility…

Machine Learning · Computer Science 2026-05-22 Stanislav R. Kirpichenko , Andrei V. Konstantinov , Lev V. Utkin

This paper describes a method for a model-based analysis of clinical safety data called multivariate Bayesian logistic regression (MBLR). Parallel logistic regression models are fit to a set of medically related issues, or response…

Methodology · Statistics 2012-10-02 William DuMouchel

When dealing with right-censored data, where some outcomes are missing due to a limited observation period, survival analysis -- known as time-to-event analysis -- focuses on predicting the time until an event of interest occurs. Multiple…

Machine Learning · Statistics 2024-10-23 Julie Alberge , Vincent Maladière , Olivier Grisel , Judith Abécassis , Gaël Varoquaux

Conventional survival analysis approaches estimate risk scores or individualized time-to-event distributions conditioned on covariates. In practice, there is often great population-level phenotypic heterogeneity, resulting from (unknown)…

Machine Learning · Statistics 2020-03-03 Paidamoyo Chapfuwa , Chunyuan Li , Nikhil Mehta , Lawrence Carin , Ricardo Henao