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Increasingly sophisticated mathematical modelling processes from Machine Learning are being used to analyse complex data. However, the performance and explainability of these models within practical critical systems requires a rigorous and…

Machine Learning · Computer Science 2020-12-08 Xingyu Zhao , Alec Banks , James Sharp , Valentin Robu , David Flynn , Michael Fisher , Xiaowei Huang

Esophageal cancer is a major cause of cancer-related mortality internationally, with high recurrence rates and poor survival even among patients treated with curative-intent surgery. Investigating relevant prognostic factors and predicting…

Machine Learning · Computer Science 2024-09-04 Yuhan Zheng , Jessie A Elliott , John V Reynolds , Sheraz R Markar , Bartłomiej W. Papież , ENSURE study group

There is currently great interest in applying neural networks to prediction tasks in medicine. It is important for predictive models to be able to use survival data, where each patient has a known follow-up time and event/censoring…

Machine Learning · Statistics 2020-02-12 Michael F. Gensheimer , Balasubramanian Narasimhan

Survival regression aims to predict the time when an event of interest will take place, typically a death or a failure. A fully parametric method [18] is proposed to estimate the survival function as a mixture of individual parametric…

Machine Learning · Computer Science 2024-04-25 Qinxin Wang , Jiayuan Huang , Junhui Li , Jiaming Liu

The Cox Proportional Hazards (PH) model is widely used in survival analysis. Recently, artificial neural network (ANN)-based Cox-PH models have been developed. However, training these Cox models with high-dimensional features typically…

Machine Learning · Computer Science 2026-01-29 Anchen Sun , Zhibin Chen , Xiaodong Cai

The computational prediction algorithm of neural network, or deep learning, has drawn much attention recently in statistics as well as in image recognition and natural language processing. Particularly in statistical application for…

Machine Learning · Statistics 2021-04-13 Yichen Jia , Jong-Hyeon Jeong

For prediction of clustered time-to-event data, we propose a new deep neural network based gamma frailty model (DNN-FM). An advantage of the proposed model is that the joint maximization of the new h-likelihood provides maximum likelihood…

Machine Learning · Statistics 2023-07-14 Hangbin Lee , IL DO HA , Youngjo Lee

Time-to-event modelling, known as survival analysis, differs from standard regression as it addresses censoring in patients who do not experience the event of interest. Despite competitive performances in tackling this problem, machine…

Machine Learning · Computer Science 2023-05-12 Vincent Jeanselme , Chang Ho Yoon , Brian Tom , Jessica Barrett

In the fight against the COVID-19 pandemic, leveraging artificial intelligence to predict disease outcomes from chest radiographic images represents a significant scientific aim. The challenge, however, lies in the scarcity of large,…

Image and Video Processing · Electrical Eng. & Systems 2026-02-16 Filippo Ruffini , Lorenzo Tronchin , Zhuoru Wu , Wenting Chen , Paolo Soda , Linlin Shen , Valerio Guarrasi

While tabular foundation models have achieved remarkable success in classification and regression, adapting them to model time-to-event outcomes for survival analysis is non-trivial due to right-censoring, where data observations may end…

Machine Learning · Computer Science 2026-02-02 Da In Kim , Wei Siang Lai , Kelly W. Zhang

Fast approximations of power flow results are beneficial in power system planning and live operation. In planning, millions of power flow calculations are necessary if multiple years, different control strategies or contingency policies are…

Machine Learning · Computer Science 2020-08-24 Florian Schaefer , Jan-Hendrik Menke , Martin Braun

The Cox Proportional Hazards (CPH) model has long been the preferred survival model for its explainability. However, to increase its predictive power beyond its linear log-risk, it was extended to utilize deep neural networks, sacrificing…

Machine Learning · Computer Science 2025-12-02 Abdallah Alabdallah , Omar Hamed , Mattias Ohlsson , Thorsteinn Rögnvaldsson , Sepideh Pashami

Lung cancer is a major cause of cancer-related deaths, and early diagnosis and treatment are crucial for improving patients' survival outcomes. In this paper, we propose to employ convolutional neural networks to model the non-linear…

Image and Video Processing · Electrical Eng. & Systems 2024-08-20 Xiawei Wang , James Sharpnack , Thomas C. M. Lee

All machine learning algorithms use a loss, cost, utility or reward function to encode the learning objective and oversee the learning process. This function that supervises learning is a frequently unrecognized hyperparameter that…

Neural and Evolutionary Computing · Computer Science 2024-11-06 Mathew Mithra Noel , Arindam Banerjee , Yug Oswal , Geraldine Bessie Amali D , Venkataraman Muthiah-Nakarajan

The aim of survival analysis in healthcare is to estimate the probability of occurrence of an event, such as a patient's death in an intensive care unit (ICU). Recent developments in deep neural networks (DNNs) for survival analysis show…

We propose a versatile framework for survival analysis that combines advanced concepts from statistics with deep learning. The presented framework is based on piecewise exponential models and thereby supports various survival tasks, such as…

Machine Learning · Computer Science 2021-03-02 Philipp Kopper , Sebastian Pölsterl , Christian Wachinger , Bernd Bischl , Andreas Bender , David Rügamer

Survival analysis models time-to-event distributions with censorship. Recently, deep survival models using neural networks have dominated due to their representational power and state-of-the-art performance. However, their "black-box"…

Machine Learning · Computer Science 2024-08-16 Xiaotong Sun , Peijie Qiu , Shengfan Zhang

Machine learning applications for longitudinal electronic health records often forecast the risk of events at fixed time points, whereas survival analysis achieves dynamic risk prediction by estimating time-to-event distributions. Here, we…

Machine Learning · Computer Science 2024-11-26 Munib Mesinovic , Peter Watkinson , Tingting Zhu

Survival prediction of cancers is crucial for clinical practice, as it informs mortality risks and influences treatment plans. However, a static model trained on a single dataset fails to adapt to the dynamically evolving clinical…

Machine Learning · Computer Science 2026-01-21 Dianzhi Yu , Conghao Xiong , Yankai Chen , Wenqian Cui , Xinni Zhang , Yifei Zhang , Hao Chen , Joseph J. Y. Sung , Irwin King

Multi-task learning (MTL) is an active field in deep learning in which we train a model to jointly learn multiple tasks by exploiting relationships between the tasks. It has been shown that MTL helps the model share the learned features…

Computer Vision and Pattern Recognition · Computer Science 2021-11-30 Akihiro Nakano , Shi Chen , Kazuyuki Demachi