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How many times a diffusing molecule can permeate across a membrane or be adsorbed on a substrate? We employ the encounter-based approach to find the statistics of adsorption or permeation events for molecular diffusion in a general…

Chemical Physics · Physics 2025-07-15 Denis S. Grebenkov

Measurements of lifetimes can be done in two ways. For very short lived particles, the width can be measured. For long lived ones, the lifetime can be directly measured, for example, using a displaced vertex. Practically, the lifetime…

High Energy Physics - Phenomenology · Physics 2009-01-06 Yuval Grossman , Itay Nachshon

For problems in astrophysics, planetary science and beyond, numerical simulations are often limited to simulating fewer particles than in the real system. To model collisions, the simulated particles (aka superparticles) need to be inflated…

Earth and Planetary Astrophysics · Physics 2020-06-03 David Nesvorny , Andrew N. Youdin , Raphael Marschall , Derek C. Richardson

Using some knowledge of multiplicity disributions for high energy reactions, it is possible to propose a simple analytical model of particle production by strong external sources. The model describes qualitatively most peculiar properties…

High Energy Physics - Phenomenology · Physics 2008-11-26 I. M. Dremin

Particle dynamics are investigated in plasma turbulence, using self-consistent kinetic simulations, in two dimensions. In steady state, the trajectories of single protons and proton-pairs are studied, at different values of plasma "beta"…

Plasma Physics · Physics 2016-08-31 S. Servidio , C. T. Haynes , W. H. Matthaeus , D. Burgess , V. Carbone , P. Veltri

The diffusion of finite-size hard-core interacting particles in two- or three-dimensional confined domains is considered in the limit that the confinement dimensions become comparable to the particle's dimensions. The result is a nonlinear…

Mathematical Physics · Physics 2017-03-23 Maria Bruna , S. Jonathan Chapman

The migration of active particles in slowly moving, crowded, and heterogeneous media is fundamental to various biological processes and technological applications, such as cargo transport. In this study, we numerically investigate the…

Soft Condensed Matter · Physics 2024-12-04 Meng-Yuan Li , Ning Zheng , Yan-Wei Li

Biomolecular folding, at least in simple systems, can be described as a two state transition in a free energy landscape with two deep wells separated by a high barrier. Transition paths are the short part of the trajectories that cross the…

Statistical Mechanics · Physics 2018-12-10 M. Laleman , E. Carlon , H. Orland

We present an efficient point-particle approach to simulate reaction-diffusion processes of spherical absorbing particles in the diffusion-limited regime, as simple models of cellular uptake. The exact solution for a single absorber is used…

Fluid Dynamics · Physics 2018-02-14 A. Sozza , F. Piazza , M. Cencini , F. De Lillo , G. Boffetta

Long DNA molecules can be mapped by cutting them with restriction enzymes inside a narrow channel. Once cut, the individual fragments thus produced move away from each other due to diffusion and entropic effects. We investigate how long it…

Soft Condensed Matter · Physics 2025-06-11 Hanyang. Wang , Gary W Slater

Single-molecule tracking is a powerful way to look at the dynamic organization of plasma membranes. However, there are some limitations to its use. For example, it was recently observed, using numerical simulation, that time-averaging…

Quantitative Methods · Quantitative Biology 2009-11-13 Nicolas Destainville , Laurence Salome

In light of the widespread success of generative models, a significant amount of research has gone into speeding up their sampling time. However, generative models are often sampled multiple times to obtain a diverse set incurring a cost…

Machine Learning · Computer Science 2023-11-27 Gabriele Corso , Yilun Xu , Valentin de Bortoli , Regina Barzilay , Tommi Jaakkola

We investigate how confinement may drastically change both the probability density of the first-encounter time and the related survival probability in the case of two diffusing particles. To obtain analytical insights into this problem, we…

Statistical Mechanics · Physics 2020-09-16 F. Le Vot , S. B. Yuste , E. Abad , D. S. Grebenkov

Diffusion in the crowded environments of the biological membranes or materials interfaces often involves intermittent binding to surface proteins or defects. To account for this situation we study a 2-dimensional lattice gas in a field of…

Soft Condensed Matter · Physics 2021-06-25 Mislav Cvitković , Dipanwita Ghanti , Niklas Raake , Ana-Sunčana Smith

Many problems in physics, biology, and economics depend upon the duration of time required for a diffusing particle to cross a boundary. As such, calculations of the distribution of first passage time, and in particular the mean first…

Biological Physics · Physics 2021-05-26 Matthew J Simpson , Daniel J Vandenheuvel , Joshua M Wilson , Scott W McCue , Elliot J Carr

Living organisms survive and multiply even though they have uncertain and incomplete information about their environment and imperfect models to predict the consequences of their actions. Bayesian models have been proposed to face this…

Emerging Technologies · Computer Science 2015-11-13 Jacques Droulez , David Colliaux , Audrey Houillon , Pierre Bessière

Robustly handling collisions between individual particles in a large particle-based simulation has been a challenging problem. We introduce particle merging-and-splitting, a simple scheme for robustly handling collisions between particles…

Graphics · Computer Science 2021-07-20 Nghia Truong , Cem Yuksel , Chakrit Watcharopas , Joshua A. Levine , Robert M. Kirby

In order to approximate the exit time of a one-dimensional diffusion process, we propose an algorithm based on a random walk. Such an algorithm was already introduced in both the Brownian context and in the Ornstein-Uhlenbeck context. Here…

Probability · Mathematics 2019-12-12 Samuel Herrmann , Nicolas Massin

We present an experimental study on the evaporation of drops on fibers. More specifically, we focus on the droplet lifetime both in quiescent air and in an air flow of constant velocity. We propose a model to describe the evaporation rate…

Fluid Dynamics · Physics 2024-12-13 Marie Corpart , Frédéric Restagno , François Boulogne

We present a model for diffusion in a molecularly crowded environment. The model consists of random barriers in percolation network. Random walks in the presence of slowly moving barriers show normal diffusion for long times, but anomalous…

Subcellular Processes · Quantitative Biology 2007-06-06 Dietrich Stauffer , Christian Schulze , Dieter W. Heermann