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Diffusion is a fundamental phenomenon that occurs ubiquitously in nature and remains the subject of continuous research interest. Understanding diffusion is a key to understanding leaving systems. In this Chapter, I discuss diffusion of…

Soft Condensed Matter · Physics 2018-10-15 Svyatoslav Kondrat

Mathematical models of diffusive transport underpin our understanding of chemical, biochemical and biological transport phenomena. Analysis of such models often focusses on relatively simple geometries and deals with diffusion through…

Biological Physics · Physics 2020-08-27 Elliot J. Carr , Jacob M. Ryan , Matthew J. Simpson

We present a multiscale approach to model diffusion in a crowded environment and its effect on the reaction rates. Diffusion in biological systems is often modeled by a discrete space jump process in order to capture the inherent noise of…

Subcellular Processes · Quantitative Biology 2016-03-18 Lina Meinecke

The transport of particles in cells is influenced by the properties of intracellular networks they traverse while searching for localized target regions or reaction partners. Moreover, given the rapid turnover in many intracellular…

Biological Physics · Physics 2024-06-21 Lachlan Elam , Mónica C. Quiñones-Frías , Ying Zhang , Avital A. Rodal , Thomas G. Fai

The first passage time for a single diffusing particle has been studied extensively, but the first passage time of a system of many diffusing particles, as is often the case in physical systems, has received little attention until recently.…

Statistical Mechanics · Physics 2024-11-22 Jacob B. Hass , Ivan Corwin , Eric I. Corwin

We study here the escape time for the fastest diffusing particle from the boundary of an interval with point-sink killing sources. Killing represents a degradation that leads to the probabilistic removal of the moving Brownian particles. We…

Statistical Mechanics · Physics 2023-02-27 Suney Toste , David Holcman

Consider a particle diffusing in a confined volume which is divided into two equal regions. In one region the diffusion coefficient is twice the value of the diffusion coefficient in the other region. Will the particle spend equal…

Dynamical Systems · Mathematics 2015-06-04 P. F. Tupper , Xin Yang

Chemical reactions inside cells are generally considered to happen within fixed-size compartments. Needless to say, cells and their compartments are highly dynamic. Thus, such stringent assumptions may not reflect biochemical reality, and…

Quantitative Methods · Quantitative Biology 2016-02-17 Atiyo Ghosh , Tatiana T. Marquez-Lago

Inside every living cell is the cytoplasm: a fluid mixture of thousands of different macromolecules, predominantly proteins. This mixture is where most of the biochemistry occurs that enables living cells to function, and it is perhaps the…

Soft Condensed Matter · Physics 2009-11-11 Richard P. Sear

We formulate a model for the dynamics of respiratory droplets and use it to study their airborne lifetime in turbulent air representative of indoor settings. This lifetime is a common metric to assess the risk of respiratory transmission of…

Medical Physics · Physics 2022-06-15 Avshalom Offner , Jacques Vanneste

Molecular diffusion measurements are widely used to probe microstructure in materials and living organisms noninvasively. The precise relation of diffusion metrics to microstructure remains a major challenge: In complex samples, it is often…

Biological Physics · Physics 2014-04-15 Dmitry S. Novikov , Els Fieremans , Jens H. Jensen , Joseph A. Helpern

The tasks of identifying separation structures and clusters in flow data are fundamental to flow visualization. Significant work has been devoted to these tasks in flow represented by vector fields, but there are unique challenges in…

Graphics · Computer Science 2017-08-15 Matthew Berger , Joshua A. Levine

The chaotic diffusion for particles moving in a time dependent potential well is described by using two different procedures: (i) via direct evolution of the mapping describing the dynamics and ; (ii) by the solution of the diffusion…

Statistical Mechanics · Physics 2020-08-26 Edson D. Leonel , Celia Mayumi Kuwana , Makoto Yoshida , Juliano Antonio de Oliveira

The diffusion of a particle in a crowded environment typically proceeds through three regimes: for very short times the particle diffuses freely until it collides with an obstacle for the first time, while for very long times diffusion the…

Biological Physics · Physics 2019-10-09 Nguiya P. Neo , Gary W. Slater

At finite concentrations of reacting molecules, kinetics of diffusion-controlled reactions is affected by intra-reactant interactions. As a result, multi-particle reaction statistics cannot be deduced from single-particle results. Here we…

Statistical Mechanics · Physics 2019-08-23 Tal Agranov , Baruch Meerson

We determine how long a diffusing particle spends in a given spatial range before it dies at an absorbing boundary. In one dimension, for a particle that starts at $x_0$ and is absorbed at $x=0$, the average residence time in the range…

Statistical Mechanics · Physics 2018-10-23 J. Randon-Furling , S. Redner

The diffusion of active microscopic organisms in complex environments plays an important role in a wide range of biological phenomena from cell colony growth to single organism transport. Here, we investigate theoretically and…

Fluid Dynamics · Physics 2018-01-16 Juan L. Aragones , Shahrzad Yazdi , Alfredo Alexander-Katz

Diffusion-mediated surface phenomena are crucial for human life and industry, with examples ranging from oxygen capture by lung alveolar surface to heterogeneous catalysis, gene regulation, membrane permeation and filtration processes.…

Statistical Mechanics · Physics 2020-08-19 Denis S. Grebenkov

We describe a concept that has the potential to change how we think about the underlying mechanisms of cell membrane electroporation (EP). Prior experimental, theoretical and modeling have emphasized a single pore lifetime as adequate for…

Biological Physics · Physics 2017-08-28 Julie V. Stern , Thiruvallur R. Gowrishankar , Kyle C. Smith , James C. Weaver

We consider a particle diffusing inside a wedge with absorbing boundaries and driven by a radial flow of incompressible fluid generated by a source at the apex. The survival probability decays as (time)^{-b} with exponent depending on the…

Fluid Dynamics · Physics 2022-08-02 P. L. Krapivsky
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