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Diabetic retinopathy (DR) is a leading cause of vision impairment worldwide, and automated grading systems play a crucial role in large-scale screening programs. However, deep learning models often exhibit degraded performance when deployed…

Computer Vision and Pattern Recognition · Computer Science 2026-04-21 Afshan Hashmi

Retinal diseases remain among the leading preventable causes of visual impairment worldwide. Automated screening based on fundus image analysis has the potential to expand access to early detection, particularly in underserved populations.…

Computer Vision and Pattern Recognition · Computer Science 2026-03-26 Ali Akram

In this work, we propose a novel microaneurysm (MA) detection for early diabetic retinopathy screening using color fundus images. Since MA usually the first lesions to appear as an indicator of diabetic retinopathy, accurate detection of MA…

Computer Vision and Pattern Recognition · Computer Science 2016-07-19 Mrinal Haloi

Diabetic retinopathy is one of the most threatening complications of diabetes that leads to permanent blindness if left untreated. One of the essential challenges is early detection, which is very important for treatment success.…

Machine Learning · Computer Science 2020-03-06 Borys Tymchenko , Philip Marchenko , Dmitry Spodarets

Vision impairment due to pathological damage of the retina can largely be prevented through periodic screening using fundus color imaging. However the challenge with large scale screening is the inability to exhaustively detect fine blood…

Machine Learning · Computer Science 2016-03-16 Debapriya Maji , Anirban Santara , Pabitra Mitra , Debdoot Sheet

Retinopathy represents a group of retinal diseases that, if not treated timely, can cause severe visual impairments or even blindness. Many researchers have developed autonomous systems to recognize retinopathy via fundus and optical…

Image and Video Processing · Electrical Eng. & Systems 2021-11-05 Taimur Hassan , Bilal Hassan , Muhammad Usman Akram , Shahrukh Hashmi , Abdel Hakim Taguri , Naoufel Werghi

Retinal fundus images play a crucial role in the early detection of eye diseases. However, the impact of technical factors on these images can pose challenges for reliable AI applications in ophthalmology. For example, large fundus cohorts…

Computer Vision and Pattern Recognition · Computer Science 2025-06-24 Sarah Müller , Lisa M. Koch , Hendrik P. A. Lensch , Philipp Berens

Diabetic retinopathy (DR) is a major cause of visual impairment, and effective treatment options depend heavily on timely and accurate diagnosis. Deep learning models have demonstrated great success identifying DR from retinal images.…

Image and Video Processing · Electrical Eng. & Systems 2025-10-02 Madhushan Ramalingam , Yaish Riaz , Priyanthi Rajamanoharan , Piyumi Dasanayaka

Early detection of cardiovascular disease risk factors is essential to alter the course of the disease. Previous studies showed that deep learning can successfully be used to detect such risk factors from retinal images. This study uses…

Image and Video Processing · Electrical Eng. & Systems 2024-10-16 Andrea Prenner

Diabetic Retinopathy (DR) is a serious microvascular complication of diabetes, and one of the leading causes of vision loss worldwide. Although automated detection and grading, with Deep Learning (DL), can reduce the burden on…

Image and Video Processing · Electrical Eng. & Systems 2026-04-06 Shramana Dey , Zahir Khan , T. A. PramodKumar , B. Uma Shankar , Ashis K. Dhara , Ramachandran Rajalakshmi , Rajiv Raman , Sushmita Mitra

Abnormalities in retinal fundus images may indicate certain pathologies such as diabetic retinopathy, hypertension, stroke, glaucoma, retinal macular edema, venous occlusion, and atherosclerosis, making the study and analysis of retinal…

Image and Video Processing · Electrical Eng. & Systems 2024-05-28 Yuzhuo Chen , Zetong Chen , Yuanyuan Liu

Purpose: Convolutional neural networks can be trained to detect various conditions or patient traits based on retinal fundus photographs, some of which, such as the patient sex, are invisible to the expert human eye. Here we propose a…

Computer Vision and Pattern Recognition · Computer Science 2023-01-18 Parsa Delavari , Gulcenur Ozturan , Ozgur Yilmaz , Ipek Oruc

Diabetic retinopathy (DR), a microvascular complication of diabetes and a leading cause of preventable blindness, is projected to affect more than 130 million individuals worldwide by 2030. Early identification is essential to reduce…

Quantitative Methods · Quantitative Biology 2025-11-12 Jophy Lin

Although deep learning based diabetic retinopathy (DR) classification methods typically benefit from well-designed architectures of convolutional neural networks, the training setting also has a non-negligible impact on the prediction…

Image and Video Processing · Electrical Eng. & Systems 2022-10-19 Yijin Huang , Li Lin , Pujin Cheng , Junyan Lyu , Roger Tam , Xiaoying Tang

Type 2 Diabetes (T2D) is a chronic metabolic disorder that can lead to blindness and cardiovascular disease. Information about early stage T2D might be present in retinal fundus images, but to what extent these images can be used for a…

Widespread outreach programs using remote retinal imaging have proven to decrease the risk from diabetic retinopathy, the leading cause of blindness in the US. However, this process still requires manual verification of image quality and…

Computer Vision and Pattern Recognition · Computer Science 2016-12-14 Arjun Raj Rajanna , Kamelia Aryafar , Rajeev Ramchandran , Christye Sisson , Ali Shokoufandeh , Raymond Ptucha

Age-related macular degeneration (AMD) is the leading cause of visual impairment among elderly in the world. Early detection of AMD is of great importance, as the vision loss caused by this disease is irreversible and permanent. Color…

Purpose: To assess the utility of deep learning in the detection of geographic atrophy (GA) from color fundus photographs; secondary aim to explore potential utility in detecting central GA (CGA). Design: A deep learning model was developed…

Image and Video Processing · Electrical Eng. & Systems 2019-06-10 Tiarnan D. Keenan , Shazia Dharssi , Yifan Peng , Qingyu Chen , Elvira Agrón , Wai T. Wong , Zhiyong Lu , Emily Y. Chew

Refractive error is the most common eye disorder and is the key cause behind correctable visual impairment, responsible for nearly 80% of the visual impairment in the US. Refractive error can be diagnosed using multiple methods, including…

Human-Computer Interaction · Computer Science 2022-08-12 Aditya Aggarwal , Siddhartha Gairola , Uddeshya Upadhyay , Akshay P Vasishta , Diwakar Rao , Aditya Goyal , Kaushik Murali , Nipun Kwatra , Mohit Jain

An overview of the applications of deep learning in ophthalmic diagnosis using retinal fundus images is presented. We also review various retinal image datasets that can be used for deep learning purposes. Applications of deep learning for…

Computer Vision and Pattern Recognition · Computer Science 2020-01-24 Sourya Sengupta , Amitojdeep Singh , Henry A. Leopold , Tanmay Gulati , Vasudevan Lakshminarayanan