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Diabetic retinopathy (DR) results in vision loss if not treated early. A computer-aided diagnosis (CAD) system based on retinal fundus images is an efficient and effective method for early DR diagnosis and assisting experts. A…

Computer Vision and Pattern Recognition · Computer Science 2019-08-23 Norah Asiri , Muhammad Hussain , Fadwa Al Adel , Nazih Alzaidi

Automated diagnosis based on color fundus photography is essential for large-scale glaucoma screening. However, existing deep learning models are typically data-driven and lack explicit integration of retinal anatomical knowledge, which…

Computer Vision and Pattern Recognition · Computer Science 2026-04-15 Yuzhuo Zhou , Chi Liu , Sheng Shen , Zongyuan Ge , Fengshi Jing , Shiran Zhang , Yu Jiang , Anli Wang , Wenjian Liu , Feilong Yang , Tianqing Zhu , Xiaotong Han

Diabetic Retinopathy (DR) is a constantly deteriorating disease, being one of the leading causes of vision impairment and blindness. Subtle distinction among different grades and existence of many significant small features make the task of…

Computer Vision and Pattern Recognition · Computer Science 2018-12-31 Sheikh Muhammad Saiful Islam , Md Mahedi Hasan , Sohaib Abdullah

Background: To determine the ability of a commercially available deep learning system, RetCAD v.1.3.1 (Thirona, Nijmegen, The Netherlands) for the automatic detection of referable diabetic retinopathy (DR) on a dataset of colour fundus…

Many diseases are classified based on human-defined rubrics that are prone to bias. Supervised neural networks can automate the grading of retinal fundus images, but require labor-intensive annotations and are restricted to the specific…

Computer Vision and Pattern Recognition · Computer Science 2020-10-26 Baladitya Yellapragada , Sascha Hornhauer , Kiersten Snyder , Stella Yu , Glenn Yiu

Previous approaches using deep learning algorithms to classify glaucomatous damage on fundus photographs have been limited by the requirement for human labeling of a reference training set. We propose a new approach using spectral-domain…

Computer Vision and Pattern Recognition · Computer Science 2018-10-25 Felipe A. Medeiros , Alessandro A. Jammal , Atalie C. Thompson

Age related macular degeneration (AMD) is one of the major causes for blindness in the elderly population. In this report, we propose deep learning based methods for retinal analysis using color fundus images for computer aided diagnosis of…

Image and Video Processing · Electrical Eng. & Systems 2020-09-04 Sharath M Shankaranarayana

Deep learning is currently the state-of-the-art for automated detection of referable diabetic retinopathy (DR) from color fundus photographs (CFP). While the general interest is put on improving results through methodological innovations,…

Image and Video Processing · Electrical Eng. & Systems 2022-10-10 Tomás Castilla , Marcela S. Martínez , Mercedes Leguía , Ignacio Larrabide , José Ignacio Orlando

Diabetic Retinopathy (DR) is a major cause of vision impairment worldwide. However, manual diagnosis is often time-consuming and prone to errors, leading to delays in screening. This paper presents a lightweight automated deep learning…

Computer Vision and Pattern Recognition · Computer Science 2026-02-26 Aadi Joshi , Manav S. Sharma , Vijay Uttam Rathod , Ashlesha Sawant , Prajakta Musale , Asmita B. Kalamkar

Replication studies are essential for validation of new methods, and are crucial to maintain the high standards of scientific publications, and to use the results in practice. We have attempted to replicate the main method in 'Development…

Computer Vision and Pattern Recognition · Computer Science 2019-06-19 Mike Voets , Kajsa Møllersen , Lars Ailo Bongo

Diabetic retinopathy is one of the leading causes of preventable blindness in the world. Its earliest sign are red lesions, a general term that groups both microaneurysms and hemorrhages. In daily clinical practice, these lesions are…

Computer Vision and Pattern Recognition · Computer Science 2017-10-16 José Ignacio Orlando , Elena Prokofyeva , Mariana del Fresno , Matthew B. Blaschko

Ultra-widefield (UWF) imaging is a promising modality that captures a larger retinal field of view compared to traditional fundus photography. Previous studies showed that deep learning (DL) models are effective for detecting retinal…

Image and Video Processing · Electrical Eng. & Systems 2022-03-14 Justin Engelmann , Alice D. McTrusty , Ian J. C. MacCormick , Emma Pead , Amos Storkey , Miguel O. Bernabeu

Machine learning is gaining significant attention as a diagnostic tool in medical imaging, particularly in the analysis of retinal fundus images. However, this approach is not yet clinically applicable, as it still depends on human…

Human-Computer Interaction · Computer Science 2025-10-03 Mattea Reid , Zuhairah Zainal , Khaing Zin Than , Danielle Chan , Jonathan Chan

The joint interpretation of multi-modal and multi-view fundus images is critical for retinopathy prevention, as different views can show the complete 3D eyeball field and different modalities can provide complementary lesion areas. Compared…

Computer Vision and Pattern Recognition · Computer Science 2025-04-15 Yonghao Huang , Leiting Chen , Chuan Zhou

Diabetic retinopathy (DR) is a prevalent complication of diabetes associated with a significant risk of vision loss. Timely identification is critical to curb vision impairment. Algorithms for DR staging from digital fundus images (DFIs)…

Image and Video Processing · Electrical Eng. & Systems 2023-12-25 Yevgeniy Men , Jonathan Fhima , Leo Anthony Celi , Lucas Zago Ribeiro , Luis Filipe Nakayama , Joachim A. Behar

Glaucoma is the leading cause of preventable, irreversible blindness world-wide. The disease can remain asymptomatic until severe, and an estimated 50%-90% of people with glaucoma remain undiagnosed. Glaucoma screening is recommended for…

Parkinson's disease is the world's fastest-growing neurological disorder. Research to elucidate the mechanisms of Parkinson's disease and automate diagnostics would greatly improve the treatment of patients with Parkinson's disease. Current…

Machine Learning · Computer Science 2024-02-20 Charlie Tran , Kai Shen , Kang Liu , Akshay Ashok , Adolfo Ramirez-Zamora , Jinghua Chen , Yulin Li , Ruogu Fang

Fundus photography is prone to suffer from image quality degradation that impacts clinical examination performed by ophthalmologists or intelligent systems. Though enhancement algorithms have been developed to promote fundus observation on…

Image and Video Processing · Electrical Eng. & Systems 2023-09-12 Heng Li , Haofeng Liu , Huazhu Fu , Yanwu Xu , Hui Shu , Ke Niu , Yan Hu , Jiang Liu

Diabetic retinopathy (DR) is a severe complication of diabetes that can cause permanent blindness. Timely diagnosis and treatment of DR are critical to avoid total loss of vision. Manual diagnosis is time consuming and error-prone. In this…

Image and Video Processing · Electrical Eng. & Systems 2021-10-05 Ramya Bygari , Rachita Naik , Uday Kumar P

Fundus photography (FP) remains the primary imaging modality in screening various retinal diseases including age-related macular degeneration, diabetic retinopathy and glaucoma. FP allows the clinician to examine the ocular fundus…

Image and Video Processing · Electrical Eng. & Systems 2023-02-21 Shanmukh Reddy Manne , Jose-Alain Sahel , Jay Chhablani , Kiran Kumar Vupparaboinab , Soumya Jana