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In this paper, we propose a recurrent neural network (RNN) with residual attention (RRA) to learn long-range dependencies from sequential data. We propose to add residual connections across timesteps to RNN, which explicitly enhances the…

Machine Learning · Computer Science 2017-09-19 Cheng Wang

The identification of DNA-binding proteins (DBPs) is essential due to their significant impact on various biological activities. Understanding the mechanisms underlying protein-DNA interactions is essential for elucidating various life…

Machine Learning · Computer Science 2026-01-27 A. Quadir , M. Sajid , M. Tanveer

A Relational Dependency Network (RDN) is a directed graphical model widely used for multi-relational data. These networks allow cyclic dependencies, necessary to represent relational autocorrelations. We describe an approach for learning…

Machine Learning · Computer Science 2014-12-10 Oliver Schulte , Zhensong Qian , Arthur E. Kirkpatrick , Xiaoqian Yin , Yan Sun

Most recent gains in visual recognition have originated from the inclusion of attention mechanisms in deep convolutional networks (DCNs). Because these networks are optimized for object recognition, they learn where to attend using only a…

Computer Vision and Pattern Recognition · Computer Science 2019-06-12 Drew Linsley , Dan Shiebler , Sven Eberhardt , Thomas Serre

Accurate pedestrian detection has a primary role in automotive safety: for example, by issuing warnings to the driver or acting actively on car's brakes, it helps decreasing the probability of injuries and human fatalities. In order to…

Computer Vision and Pattern Recognition · Computer Science 2018-08-09 Denis Tome' , Luca Bondi , Emanuele Plebani , Luca Baroffio , Danilo Pau , Stefano Tubaro

Understanding protein-metal interactions is central to structural biology, with metal ions being vital for catalysis, stability, and signal transduction. Predicting metal-binding residues and metal types remains challenging due to the…

Machine Learning · Computer Science 2026-02-23 Sayedmohammadreza Rastegari , Sina Tabakhi , Xianyuan Liu , Tianyi Jiang , Wei Sang , Haiping Lu

Empirical scoring functions based on either molecular force fields or cheminformatics descriptors are widely used, in conjunction with molecular docking, during the early stages of drug discovery to predict potency and binding affinity of a…

Machine Learning · Computer Science 2017-03-31 Joseph Gomes , Bharath Ramsundar , Evan N. Feinberg , Vijay S. Pande

We proposed a deep learning method for interpretable diabetic retinopathy (DR) detection. The visual-interpretable feature of the proposed method is achieved by adding the regression activation map (RAM) after the global averaging pooling…

Computer Vision and Pattern Recognition · Computer Science 2019-12-04 Zhiguang Wang , Jianbo Yang

In this work, we aim to predict human eye fixation with view-free scenes based on an end-to-end deep learning architecture. Although Convolutional Neural Networks (CNNs) have made substantial improvement on human attention prediction, it is…

Computer Vision and Pattern Recognition · Computer Science 2018-03-26 Wenguan Wang , Jianbing Shen

In recent years, channel attention mechanism has been widely investigated due to its great potential in improving the performance of deep convolutional neural networks (CNNs) in many vision tasks. However, in most of the existing methods,…

Computer Vision and Pattern Recognition · Computer Science 2022-06-02 Yue Zhao , Junzhou Chen , Zirui Zhang , Ronghui Zhang

Identifying transcription factor binding sites (TFBS) is crucial for understanding gene regulation, as these sites enable transcription factors (TFs) to bind to DNA and modulate gene expression. Despite advances in high-throughput…

Machine Learning · Computer Science 2025-03-18 Jonas Chris Ferrao , Dickson Dias , Sweta Morajkar , Manisha Gokuldas Fal Dessai

Summary: We introduce RBPBind, a web-based tool for the quantitative prediction of RNA-protein interactions. Given a user-specified RNA and a protein selected from a set of several common RNA-binding proteins, RBPBind computes the binding…

Biomolecules · Quantitative Biology 2016-11-07 Jeff Gaither , Yi-Hsuan Lin , Ralf Bundschuh

Composed of amino acid chains that influence how they fold and thus dictating their function and features, proteins are a class of macromolecules that play a central role in major biological processes and are required for the structure,…

Quantitative Methods · Quantitative Biology 2022-07-15 Aaron Wang

Porting state of the art deep learning algorithms to resource constrained compute platforms (e.g. VR, AR, wearables) is extremely challenging. We propose a fast, compact, and accurate model for convolutional neural networks that enables…

Computer Vision and Pattern Recognition · Computer Science 2017-06-14 Hessam Bagherinezhad , Mohammad Rastegari , Ali Farhadi

DNA-binding proteins are a class of proteins which have a specific or general affinity to DNA and include three important components: transcription factors; nucleases, and histones. DNA-binding proteins also perform important roles in many…

Computer Vision and Pattern Recognition · Computer Science 2012-07-12 Sokyna Qatawneh , Afaf Alneaimi , Thamer Rawashdeh , Mmohammad Muhairat , Rami Qahwaji , Stan Ipson

In this article we investigate the efficiency of deep learning algorithms in solving the task of detecting anatomical reference points on radiological images of the head in lateral projection using a fully convolutional neural network and a…

Image and Video Processing · Electrical Eng. & Systems 2020-06-19 Konstantin Dobratulin , Andrey Gaidel , Irina Aupova , Anna Ivleva , Aleksandr Kapishnikov , Pavel Zelter

Whereas deep neural networks were first mostly used for classification tasks, they are rapidly expanding in the realm of structured output problems, where the observed target is composed of multiple random variables that have a rich joint…

Neural and Evolutionary Computing · Computer Science 2016-11-15 Kyunghyun Cho , Aaron Courville , Yoshua Bengio

Convolutional neural networks (CNNs) have proven effective for image processing tasks, such as object recognition and classification. Recently, CNNs have been enhanced with concepts of attention, similar to those found in biology. Much of…

Computer Vision and Pattern Recognition · Computer Science 2015-12-10 Grace W. Lindsay

Motivation: MicroRNAs (miRNAs) play pivotal roles in gene expression regulation by binding to target sites of messenger RNAs (mRNAs). While identifying functional targets of miRNAs is of utmost importance, their prediction remains a great…

Genomics · Quantitative Biology 2021-10-14 Seonwoo Min , Byunghan Lee , Sungroh Yoon

Protein function prediction is a crucial task in bioinformatics, with significant implications for understanding biological processes and disease mechanisms. While the relationship between sequence and function has been extensively…

Quantitative Methods · Quantitative Biology 2024-09-04 Shania Mitra , Lei Huang , Manolis Kellis