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Modern machine learning models are deployed in diverse, non-stationary environments where they must continually adapt to new tasks and evolving knowledge. Continual fine-tuning and in-context learning are costly and brittle, whereas neural…

Machine Learning · Computer Science 2026-03-04 Max S. Bennett , Thomas P. Zollo , Richard Zemel

Pulse-modulated feedback is utilized in drug dosing to mimic sustained over a longer period of time manual discrete dose administration, the latter is in contrast with continuous drug infusion. The intermittent mode of dosing calls for a…

Dynamical Systems · Mathematics 2025-02-28 Alexander Medvedev , Anton V. Proskurnikov , Zhanybai T. Zhusubaliyev

Clinical decision support systems have been developed to help physicians to take clinical guidelines into account during consultations. The ASTI critiquing module is one such systems; it provides the physician with automatic criticisms when…

In continual learning, there is a serious problem of catastrophic forgetting, in which previous knowledge is forgotten when a model learns new tasks. Various methods have been proposed to solve this problem. Replay methods which replay data…

Computer Vision and Pattern Recognition · Computer Science 2024-09-18 Kotaro Nagata , Hiromu Ono , Kazuhiro Hotta

Motivated by a clinical trial conducted by Janssen Pharmaceuticals in which a flexible dosing regimen is compared to placebo, we evaluate how switchers in the treatment arm (i.e., patients who were switched to the higher dose) would have…

Methodology · Statistics 2020-09-07 Kelly Van Lancker , An Vandebosch , Stijn Vansteelandt

The process of electronic approach to writing and sending medical prescription promises to improve patient safety, health outcomes, maintaining patients privacy, promoting clinician acceptance and prescription security when compared with…

Computers and Society · Computer Science 2015-06-12 Adebayo Omotosho , Emuoyibofarhe Justice

Simulation is a useful tool in situations where training data for machine learning models is costly to annotate or even hard to acquire. In this work, we propose a reinforcement learning-based method for automatically adjusting the…

Machine Learning · Computer Science 2019-05-15 Nataniel Ruiz , Samuel Schulter , Manmohan Chandraker

In this paper, a multi-model predictive control approach is used to automate the co-administration of propofol and remifentanil from bispectral index measurement during general anesthesia. To handle the parameter uncertainties in the…

Systems and Control · Electrical Eng. & Systems 2023-09-18 Bob Aubouin-Pairault , Mirko Fiacchini , Thao Dang

The early development and deployment of hospital and healthcare information systems have encouraged the ongoing digitization of processes in hospitals. Many of these processes, which previously required paperwork and telephone arrangements,…

Computers and Society · Computer Science 2022-09-09 Daniel Schlör , Andreas Hotho

With people living longer than ever, the number of cases with dementia such as Alzheimer's disease increases steadily. It affects more than 46 million people worldwide, and it is estimated that in 2050 more than 100 million will be…

Multimedia · Computer Science 2021-01-20 Mariona Caros , Maite Garolera , Petia Radeva , Xavier Giro-i-Nieto

Memory refinements are designed below to detect those sequences of actions that have been repeated a given number n. Subsequently such sequences are permitted to run without CPU involvement. This mimics human learning. Actions are rehearsed…

Artificial Intelligence · Computer Science 2010-09-07 John Robert Burger

Industrial timetabling is a critical task for decision-makers across various sectors to ensure efficient system operation. In real-world settings, it remains challenging because unexpected events often disrupt execution. When such events…

Human-Computer Interaction · Computer Science 2026-01-13 Kévin Ducharlet , Liwen Zhang , Sara Maqrot , Houssem Saidi

Every year, millions of pounds of medicines remain unused in the U.S. and are subject to an in-home disposal, i.e., kept in medicine cabinets, flushed in toilet or thrown in regular trash. In-home disposal, however, can negatively impact…

Computer Vision and Pattern Recognition · Computer Science 2020-07-29 Bahram Marami , Atabak Reza Royaee

Background: Phase I trials desire to identify the maximum tolerated dose (MTD) early and proceed quickly to an expansion cohort or phase II trial for efficacy. We propose an early completion method based on multiple dosages to accelerate…

Quantitative Methods · Quantitative Biology 2021-10-04 Masahiro Kojima

This paper presents the development of an electronic prescription system for pediatricians that considered the factors that influence a childs prescription. The system implements a knowledge base which contains drug information and…

Computers and Society · Computer Science 2017-07-11 Adebayo Omotosho , Ukeme Asanga , Aderogba Fakorede

Calculating mealtime insulin doses poses a significant challenge for individuals with Type 1 Diabetes (T1D). Doses should perfectly compensate for expected post-meal glucose excursions, requiring a profound understanding of the individual's…

Quantitative Methods · Quantitative Biology 2024-06-24 Anas El Fathi , Elliott Pryor , Marc D. Breton

Modern recommendation systems rely on the wisdom of the crowd to learn the optimal course of action. This induces an inherent mis-alignment of incentives between the system's objective to learn (explore) and the individual users' objective…

Computer Science and Game Theory · Computer Science 2018-07-06 Gal Bahar , Rann Smorodinsky , Moshe Tennenholtz

Background: Accurate segmentation of microscopic structures such as bio-artificial capsules in microscopy imaging is a prerequisite to the computer-aided understanding of important biomechanical phenomenons. State-of-the-art segmentation…

Computer Vision and Pattern Recognition · Computer Science 2023-01-10 Arnaud Deleruyelle , Cristian Versari , John Klein

The growing global population of older adults, combined with ongoing healthcare workforce shortages, has increased reliance on informal caregivers, including family members and friends who provide unpaid support to individuals with chronic…

Human-Computer Interaction · Computer Science 2025-12-04 Zhiyin Zhou

Parkinson's Disease (PD) medication management presents unique challenges due to heterogeneous disease progression and treatment response. Neurologists must balance symptom control with optimal dopaminergic dosing based on functional…

Machine Learning · Computer Science 2025-08-15 Ricardo Diaz-Rincon , Muxuan Liang , Adolfo Ramirez-Zamora , Benjamin Shickel