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We present in this article a novel Lagrangian measurement technique: an instrumented particle which continuously transmits the force/acceleration acting on it as it is advected in a flow. We develop signal processing methods to extract…

In applications of optical multipass cells in photochemical reactors and laser excitation of weak transitions, estimation of the radiation dose in a volume of interest allows to assess the performance and optimize the design of the cell. We…

Flow cytometry (FCM) is the standard multi-parameter assay for measuring single cell phenotype and functionality. It is commonly used for quantifying the relative frequencies of cell subsets in blood and disaggregated tissues. A typical…

Applications · Statistics 2020-09-01 Shai Gorsky , Cliburn Chan , Li Ma

Flow cytometry (FCM) is an analytic technique that is capable of detecting and recording the emission of fluorescence and light scattering of cells or particles (that are collectively called "events") in a population. A typical FCM…

Quantitative Methods · Quantitative Biology 2020-11-20 Nathan Wong , Daehwan Kim , Zachery Robinson , Connie Huang , Irina M. Conboy

Actigraphy has been widely used for the analysis of circadian rhythm. Current practice applies regression analysis to data from multiple days to estimate the circadian phase. This paper presents a filtering method for online processing of…

Systems and Control · Computer Science 2018-04-03 Wei Qiao , Kyle Altman , Agung Julius , Bernard Possidente , John T. Wen

In this paper, we introduce the notion of Gaussian processes indexed by probability density functions for extending the Mat\'ern family of covariance functions. We use some tools from information geometry to improve the efficiency and the…

Methodology · Statistics 2020-11-09 A. Fradi , Y. Feunteun , C. Samir , M. Baklouti , F. Bachoc , J-M. Loubes

Critical slowing down and topological freezing severely hinder Monte Carlo sampling of lattice field theories as the continuum limit is approached. Recently, significant progress has been made in applying a class of generative machine…

High Energy Physics - Lattice · Physics 2024-01-25 Gurtej Kanwar

Gaussian processes are a key component of many flexible statistical and machine learning models. However, they exhibit cubic computational complexity and high memory constraints due to the need of inverting and storing a full covariance…

Machine Learning · Statistics 2025-10-07 Teemu Härkönen , Sara Wade , Kody Law , Lassi Roininen

Increasing demand for understanding the vast heterogeneity of cellular phenotypes has driven the development of imaging flow cytometry (IFC), that combines features of flow cytometry with fluorescence and bright field microscopy. IFC…

Quantitative Methods · Quantitative Biology 2019-02-06 Yuanyuan Han , Rui Tang , Yi Gu , Alex Ce Zhang , Wei Cai , Violet Castor , Sung Hwan Cho , William Alaynick , Yu-Hwa Lo

While aquaporin (AQP) gating dynamically regulates transmembrane water permeability for cellular homeostasis, its mechanisms remain poorly understood compared to ion channels. A central challenge is the lack of methods to measure water flow…

Biological Physics · Physics 2025-08-04 Hong Jiang , Jinnawat Jongkhumkrong , Y. J. Chao , Qian Wang , Guiren Wang

Generative approaches to clustering provide information on geometric properties of clusters, whereas discriminative approaches provide boundaries between clusters. Ideas from both approaches are incorporated to present a fully unsupervised,…

Machine Learning · Statistics 2026-04-28 Mackenzie R. Neal , Paul D. McNicholas , Arthur White

Advances in computational science offer a principled pipeline for predictive modeling of cardiovascular flows and aspire to provide a valuable tool for monitoring, diagnostics and surgical planning. Such models can be nowadays deployed on…

Machine Learning · Computer Science 2019-09-19 Georgios Kissas , Yibo Yang , Eileen Hwuang , Walter R. Witschey , John A. Detre , Paris Perdikaris

Gait analysis is the study of the systematic methods that assess and quantify animal locomotion. Gait finds a unique importance among the many state-of-the-art biometric systems since it does not require the subject's cooperation to the…

Computer Vision and Pattern Recognition · Computer Science 2021-11-15 Ebenezer R. H. P. Isaac

In this paper, a second-order accurate method was developed for calculating fluid flows in complex geometries. This method uses cut-Cartesian cell mesh in finite volume framework. Calculus is employed to relate fluxes and gradients along…

Numerical Analysis · Mathematics 2023-04-11 Zhaohui Qin

Material Flow Analysis (MFA) is used to quantify and understand the life cycles of materials from production to end of use, which enables environmental, social and economic impacts and interventions. MFA is challenging as available data is…

Flowgraph models provide an alternative approach in modeling a multi-state stochastic process. One of the most widely used stochastic processes that have many real-world applications especially in actuarial models is the Markov jump process…

Applications · Statistics 2016-11-07 Muhammad Fikri Budiana , Murwan H. M. A. Siddig

Information flow analysis has largely ignored the setting where the analyst has neither control over nor a complete model of the analyzed system. We formalize such limited information flow analyses and study an instance of it: detecting the…

Cryptography and Security · Computer Science 2014-05-13 Michael Carl Tschantz , Amit Datta , Anupam Datta , Jeannette M. Wing

We present cytometric classification of live healthy and cancer cells by using the spatial morphological and textural information found in the label-free quantitative phase images of the cells. We compare both healthy cells to primary tumor…

Quantitative Methods · Quantitative Biology 2020-01-23 Darina Roitshtain , Lauren Wolbromsky , Evgeny Bal , Hayit Greenspan , Lisa L. Satterwhite , Natan T. Shaked

Molecular motion through pores plays a crucial role in various natural and industrial processes. One of the most fascinating features of biological channel-facilitated transport is a stochastic gating process, when the channels dynamically…

Chemical Physics · Physics 2018-12-20 Aram Davtyan , Anatoly B. Kolomeisky

We present a formulation of flow matching as variational inference, which we refer to as variational flow matching (VFM). Based on this formulation we develop CatFlow, a flow matching method for categorical data. CatFlow is easy to…

Machine Learning · Computer Science 2025-08-19 Floor Eijkelboom , Grigory Bartosh , Christian Andersson Naesseth , Max Welling , Jan-Willem van de Meent