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Asymmetric partition of fate determinants during cell division is a hallmark of cell differentiation. Recent work suggested that such a mechanism is hijacked by cancer cells to increase both their phenotypic heterogeneity and plasticity and…

Flow cytometry is often used to characterize the malignant cells in leukemia and lymphoma patients, traced to the level of the individual cell. Typically, flow cytometric data analysis is performed through a series of 2-dimensional…

Machine Learning · Statistics 2009-11-13 Kevin M. Carter , Raviv Raich , William G. Finn , Alfred O. Hero

Mathematical models of a cellular action potential in cardiac modelling have become increasingly complex, particularly in gating kinetics which control the opening and closing of individual ion channel currents. As cardiac models advance…

Quantitative Methods · Quantitative Biology 2021-04-28 C. Houston , B. Marchand , L. Engelbert , C. D. Cantwell

High-throughput screening using cell images is an efficient method for screening new candidates for pharmaceutical drugs. To complete the screening process, it is essential to have an efficient process for analyzing cell images. This paper…

Computer Vision and Pattern Recognition · Computer Science 2024-02-28 Mizuki Fukasawa , Tomokazu Fukuda , Takuya Akashi

For accurate simulations of rarefied gas flows around moving obstacles, we propose a cut cell method on Cartesian grids: it allows exact conservation and accurate treatment of boundary conditions. Our approach is designed to treat Cartesian…

Numerical Analysis · Mathematics 2016-04-20 Guillaume Dechristé , Luc Mieussens

Medical image segmentation is referred to the segmentation of known anatomic structures from different medical images. Normally, the medical data researches are more complicated and an exclusive structures. This computer aided diagnosis is…

Computer Vision and Pattern Recognition · Computer Science 2013-03-05 A. Meena , K. Raja

While analysing rare blood cell aggregates remains challenging in automated haematology, they could markedly advance label-free functional diagnostics. Conventional flow cytometers efficiently perform cell counting with leukocyte…

We combine confocal imaging, microfluidics and image analysis to record 3D-images of cells in flow. This enables us to recover the full 3D representation of several hundred living cells per minute. Whereas 3D confocal imaging has thus far…

Fluid Dynamics · Physics 2017-09-19 S. Quint , A. F. Christ , A. Guckenberger , S. Himbert , L. Kaestner , S. Gekle , C. Wagner

We present a wide-field multi-pass implementation of label-free imaging flow cytometry. Our technique is shown for high-speed flow imaging of ensembles of human red blood cells with up to four passes, demonstrating x4 enhancement in…

We present an approach for flux analysis in process algebra models of biological systems. We perceive flux as the flow of resources in stochastic simulations. We resort to an established correspondence between event structures, a broadly…

Computational Engineering, Finance, and Science · Computer Science 2010-02-23 Ozan Kahramanoğullari

Flow analysis carried out using phase contrast cardiac magnetic resonance imaging (PC-CMR) enables the quantification of important parameters that are used in the assessment of cardiovascular function. An essential part of this analysis is…

The great majority of current voice technology applications relies on acoustic features characterizing the vocal tract response, such as the widely used MFCC of LPC parameters. Nonetheless, the airflow passing through the vocal folds, and…

Sound · Computer Science 2020-01-01 Thomas Drugman , Paavo Alku , Abeer Alwan , Bayya Yegnanarayana

Modern single-cell flow and mass cytometry technologies measure the expression of several proteins of the individual cells within a blood or tissue sample. Each profiled biological sample is thus represented by a set of hundreds of…

Machine Learning · Computer Science 2022-06-29 Siyuan Shan , Vishal Baskaran , Haidong Yi , Jolene Ranek , Natalie Stanley , Junier Oliva

We present a method for a real time visualization and automatic processing for detection and classification of untouched cancer cells in blood during stain free imaging flow cytometry using digital holographic microscopy and machine…

Biological Physics · Physics 2021-06-15 Noga Nissim , Matan Dudaie , Itay Barnea. , Natan T. Shaked

We present applications of modal analysis techniques to study, model, and control canonical aerodynamic flows. To illustrate how modal analysis techniques can provide physical insights in a complementary manner, we selected four fundamental…

The pathway is a biological term that refers to a series of interactions between molecules in a cell that causes a certain product or a change in the cell. Pathway analysis is a powerful method for gene expression analysis. Through pathway…

Data Structures and Algorithms · Computer Science 2022-01-11 Lingran Xiao , Yanfei Wang , Shiying Li , Lingxi Chen , Shuaicheng Li

Gaussian processes are a versatile framework for learning unknown functions in a manner that permits one to utilize prior information about their properties. Although many different Gaussian process models are readily available when the…

The goal of this paper is to unify the lookdown representation and the stochastic flow of bridges, which are two approaches to construct the $\Lambda$-Fleming-Viot process along with its genealogy. First we introduce the stochastic flow of…

Probability · Mathematics 2014-06-27 Cyril Labbé

We introduce a model of hadronization based on invertible neural networks that faithfully reproduces a simplified version of the Lund string model for meson hadronization. Additionally, we introduce a new training method for normalizing…

High Energy Physics - Phenomenology · Physics 2024-08-14 Christian Bierlich , Phil Ilten , Tony Menzo , Stephen Mrenna , Manuel Szewc , Michael K. Wilkinson , Ahmed Youssef , Jure Zupan

A crucial building block for quantum information processing with trapped ions is a controlled-NOT quantum gate. In this paper, two different sequences of laser pulses implementing such a gate operation are analyzed using quantum process…

Quantum Physics · Physics 2009-01-15 M. Riebe , K. Kim , P. Schindler , T. Monz , P. O. Schmidt , T. K. Koerber , W. Haensel , H. Haeffner , C. F. Roos , R. Blatt