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Related papers: A phase field approach to trabecular bone remodeli…

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A model of multicellular systems with several types of cells is developed from the phase field model. The model is presented as a set of partial differential equations of the field variables, each of which expresses the shape of one cell.…

Biological Physics · Physics 2015-05-30 Makiko Nonomura

Studying cell morphology changes in time is critical to understanding cell migration mechanisms. In this work, we present a deep learning-based workflow to segment cancer cells embedded in 3D collagen matrices and imaged with phase-contrast…

Computer Vision and Pattern Recognition · Computer Science 2021-12-17 Estibaliz Gómez-de-Mariscal , Hasini Jayatilaka , Özgün Çiçek , Thomas Brox , Denis Wirtz , Arrate Muñoz-Barrutia

In this work, two-dimensional simulations of the microwave dielectric properties of models with ellipses and realistic models of trabecular bone tissue are performed. In these simulations, finite difference time domain methodology has been…

Medical Physics · Physics 2019-07-30 Ramiro M. Irastorza , C. Manuel Carlevaro , Fernando Vericat

For the study of complex synthetic and biological molecular systems by computer simulations one is still restricted to simple model systems or to by far too small time scales. To overcome this problem multiscale techniques are being…

Statistical Mechanics · Physics 2007-05-23 Matej Praprotnik , Kurt Kremer , Luigi Delle Site

We investigate the potential of quasi-Newton methods in facilitating convergence of monolithic solution schemes for phase field fracture modelling. Several paradigmatic boundary value problems are addressed, spanning the fields of…

Numerical Analysis · Mathematics 2019-12-19 Philip K. Kristensen , Emilio Martínez-Pañeda

In this work, we develop an adaptive algorithm for the efficient numerical solution of the minimum compliance problem in topology optimization. The algorithm employs the phase field approximation and continuous density field. The adaptive…

Optimization and Control · Mathematics 2024-04-18 Bangti Jin , Jing Li , Yifeng Xu , Shengfeng Zhu

Porous structures are materials consisting of minuscule pores, where the microstructure morphology significantly impacts their macroscopic properties. Integrating different porous structures through a blending method is indispensable to…

Graphics · Computer Science 2024-06-03 Depeng Gao , Yang Gao , Yuanzhi Zhang , Hongwei Lin

We study local approximation properties in hierarchical spline spaces through a twofold approach. First, we design and analyze a robust adaptive refinement algorithm to construct locally graded meshes. Second, we establish rigorous…

Numerical Analysis · Mathematics 2026-04-22 Gustavo A. Fernandez Lezcano , Eduardo M. Garau , Bárbara Ivaniszyn

Adaptive Finite Element Method (adaptivity) is known to be an effective numerical tool for some ill-posed problems. The key advantage of the adaptivity is the image improvement with local mesh refinements. A rigorous proof of this property…

Mathematical Physics · Physics 2012-10-30 Larisa Beilina , Michael V. Klibanov

This work concerns a structural topology optimisation problem for 4D printing based on the phase field approach. The concept of 4D printing as a targeted evolution of 3D printed structures can be realised in a two-step process. One first…

Optimization and Control · Mathematics 2023-05-03 Harald Garcke , Kei Fong Lam , Robert Nürnberg , Andrea Signori

We briefly review the state-of-the-art in phase-field modeling of microstructure evolution. The focus is placed on recent applications of phase-field simulations of solid-state microstructure evolution and solidification that have been…

Materials Science · Physics 2021-10-14 D. Tourret , H. Liu , J. LLorca

Throughout the process of aging, deterioration of bone macro- and micro-architecture, as well as material decomposition result in a loss of strength and therefore in an increased likelihood of fractures. To date, precise contributions of…

Quantitative Methods · Quantitative Biology 2020-02-19 Pouyan Asgharzadeh , Oliver Röhrle , Bettina M. Willie , Annette I. Birkhold

We advance a combined filtered/phase-field approach to topology optimization in the setting of linearized elasticity. Existence of minimizers is proved and rigorous parameter asymptotics are discussed by means of variational convergence…

Optimization and Control · Mathematics 2024-01-24 Ferdinando Auricchio , Michele Marino , Idriss Mazari , Ulisse Stefanelli

A multiscale scheme combining molecular dynamics (MD) and microscopic phase-field theory is proposed to study the structural phase transformations in solids with inhomogeneous strain field. The approach calculates strain response based on…

Materials Science · Physics 2007-05-23 Zhi-Rong Liu , Huajian Gao

We present a new phase field crystal model for structural transformations in multi-component alloys. The formalism builds upon the two-point correlation kernel developed in Greenwood et al. for describing structural transformations in pure…

Materials Science · Physics 2015-06-12 Nana Ofori-Opoku , Vahid Fallah , Michael Greenwood , Shahrzad Esmaeili , Nikolas Provatas

The outcome of vertebroplasty is hard to predict due to its dependence on complex factors like bone cement and marrow rheologies. Cement leakage could occur if the procedure is done incorrectly, potentially causing adverse complications. A…

Reconstructing the surfaces of deformable objects from correspondences between a 3D template and a 2D image is well studied under Shape-from-Template (SfT) methods; however, existing approaches break down when topological changes accompany…

Computer Vision and Pattern Recognition · Computer Science 2025-11-06 Kevin Manogue , Tomasz M Schang , Dilara Kuş , Jonas Müller , Stefan Zachow , Agniva Sengupta

Shape reconstruction from imaging volumes is a recurring need in medical image analysis. Common workflows start with a segmentation step, followed by careful post-processing and,finally, ad hoc meshing algorithms. As this sequence can be…

Computer Vision and Pattern Recognition · Computer Science 2025-07-11 Antonio Pepe , Richard Schussnig , Jianning Li , Christina Gsaxner , Dieter Schmalstieg , Jan Egger

Remodelling of biological tissue, due to changes in microstructure, is treated in the continuum mechanical setting. Microstructural change is expressed as an evolution of the reference configuration. This evolution is expressed as a…

Quantitative Methods · Quantitative Biology 2007-05-23 K. Garikipati , H. Narayanan , E. M. Arruda , K. Grosh , S. Calve

This paper presents a phase-field model for simulating the three-dimensional deformation of vesicle membranes, incorporating area-difference elasticity, with constraints on bulk volume and surface area. We develop efficient numerical…

Numerical Analysis · Mathematics 2025-11-19 Yihong Liang , Emine Celiker , Ping Lin
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