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Cortical bone is a tough biological material composed of tube-like osteons embedded in the organic matrix surrounded by weak interfaces known as cement lines. The cement lines provide a microstructurally preferable crack path, hence…

Applied Physics · Physics 2024-05-24 Shashank Gupta , Reza Moini

Fracture is a fundamental mechanism of materials failure. Propagating cracks can exhibit a rich dynamical behavior controlled by a subtle interplay between microscopic failure processes in the crack tip region and macroscopic elasticity. We…

Materials Science · Physics 2015-05-18 R. Spatschek , E. Brener , A. Karma

Wide variety of engineering design tasks can be formulated as constrained optimization problems where the shape and topology of the domain are optimized to reduce costs while satisfying certain constraints. Several mathematical approaches…

Optimization and Control · Mathematics 2015-03-10 Igor Ostanin , Denis Zorin , Ivan Oseledets

Accurate segmentation of topological tubular structures, such as blood vessels and roads, is crucial in various fields, ensuring accuracy and efficiency in downstream tasks. However, many factors complicate the task, including thin local…

Computer Vision and Pattern Recognition · Computer Science 2023-08-21 Yaolei Qi , Yuting He , Xiaoming Qi , Yuan Zhang , Guanyu Yang

Tube-like surfaces are widely encountered in geometry processing, engineering structures, and medical anatomy, yet their intrinsic longitudinal and circumferential topology is not well preserved by conventional planar annular or rectangular…

Graphics · Computer Science 2026-05-19 Shunyu Yao , Gary P. T. Choi

The scaled boundary finite element method (SBFEM) has recently been employed as an efficient means to model three-dimensional structures, in particular when the geometry is provided as a voxel-based image. To this end, an octree…

Numerical Analysis · Mathematics 2023-10-31 Hauke Gravenkamp , Albert A. Saputra , Sascha Eisenträger

A new approach is developed for computational modelling of microstructure evolution problems. The approach combines the phase-field method with the recently-developed laminated element technique (LET) which is a simple and efficient method…

Numerical Analysis · Mathematics 2024-02-29 Jedrzej Dobrzanski , Stanislaw Stupkiewicz

The development of novel materials in recent years has been accelerated greatly by the use of computational modelling techniques aimed at elucidating the complex physics controlling microstructure formation in materials, the properties of…

Materials Science · Physics 2025-11-14 Damien Pinto , Michael Greenwood , Nikolas Provatas

We propose and analyze an adaptive finite element method for a phase-field model of dynamic brittle fracture. The model couples a second-order hyperbolic equation for elastodynamics with the Ambrosio-Tortorelli regularization of the…

Numerical Analysis · Mathematics 2025-10-08 Ram Manohar , S. M. Mallikarjuaniah

We present a simple set of data structures, and a collection of methods for constructing and updating the structures, designed to support the use of cohesive elements in simulations of fracture and fragmentation. Initially all interior…

Materials Science · Physics 2016-08-31 Anna Pandolfi , Michael Ortiz

Computer-aided design (CAD) models play a crucial role in the design, manufacturing and maintenance of products. Therefore, the mesh-based finite element descriptions common in structural optimisation must be first translated into CAD…

Graphics · Computer Science 2020-07-15 Ge Yin , Xiao Xiao , Fehmi Cirak

We introduce a model checking approach to diagnose the emerging of bone pathologies. The implementation of a new model of bone remodeling in PRISM has led to an interesting characterization of osteoporosis as a defective bone remodeling…

Logic in Computer Science · Computer Science 2011-11-10 Pietro Liò , Emanuela Merelli , Nicola Paoletti

The complexity and heterogeneity of bone tissue require a multiscale modelling to understand its mechanical behaviour and its remodelling mechanisms. In this paper, a novel multiscale hierarchical approach including microfibril scale based…

Medical Physics · Physics 2014-03-13 Abdelwahed Barkaoui , Abdessalem Chamekh , Merzouki Tarek , Ridha Hambli , Mkaddem Ali

The accurate modeling of biological processes allows to predict the spatio-temporal behavior of living tissues by computer-aided (in-silico) testing, a useful tool for the development of medical strategies, avoiding the expenses and…

The modeling of large deformation fracture mechanics has been a challenging problem regarding the accuracy of numerical methods and their ability to deal with considerable changes in deformations of meshes where having the presence of…

Numerical Analysis · Computer Science 2019-03-21 Hai D. Huynh , Phuong Tran , Xiaoying Zhuang , H. Nguyen-Xuan

The measurement of cellular traction forces on soft elastic substrates has become a standard tool for many labs working on mechanobiology. Here we review the basic principles and different variants of this approach. In general, the…

Quantitative Methods · Quantitative Biology 2015-06-09 Ulrich S. Schwarz , Jerome R. D. Soine

Chaotic free surface flows are challenging problems to simulate numerically, mainly due to the significant changes in geometry and frequent topological changes. Methods that track the evolution of the fluid in a Lagrangian formulation are a…

Fluid Dynamics · Physics 2025-12-24 Thomas Leyssens , Jonathan Lambrechts , Jean-François Remacle

While biological crystallization processes have been studied on the microscale extensively, models addressing the mesoscale aspects of such phenomena are rare. In this work, we investigate whether the phase-field theory developed in…

This research rigorously investigates the convergence of adaptive finite element methods for regularized variational models of quasi-static brittle fracture in elastic solids. We specifically examine a novel Ambrosio-Tortorelli (AT1)…

Numerical Analysis · Mathematics 2025-07-02 Ram Manohar , S. M. Mallikarjunaiah

This work presents a reduced order modelling technique built on a high fidelity embedded mesh finite element method. Such methods, and in particular the CutFEM method, are attractive in the generation of projection-based reduced order…

Numerical Analysis · Mathematics 2023-08-08 Efthymios N. Karatzas , Francesco Ballarin , Gianluigi Rozza
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