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Knowledge of x-ray attenuation is essential for developing and evaluating x-ray imaging technologies. In mammography, measurement of breast density, dose estimation, and differentiation between cysts and solid tumours are example…

Cosmic-ray positrons have long been considered a powerful probe of dark matter annihilation. In particular, myriad studies of the unexpected rise in the positron fraction have debated its dark matter or pulsar origins. In this paper, we…

High Energy Astrophysical Phenomena · Physics 2022-01-07 Isabelle John , Tim Linden

Histopathology, the study and diagnosis of disease through analysis of tissue samples, is an indispensable part of modern medicine. However, the practice is time consuming and labor intensive, compelling efforts to improve the process and…

A brief review is given of recent positron studies of metal and semiconductor nanocrystals. The prospects offered by positron annihilation as a sensitive method to access nanocrystal (NC) properties are described and compared with other…

Materials Science · Physics 2007-10-11 S. W. H. Eijt , B. Barbiellini , A. J. Houtepen , D. Vanmaekelbergh , P. E. Mijnarends , A. Bansil

Positron Emission Tomography (PET) is a Nuclear Medicine technique that creates images that allow the study of metabolic activity and organ function using radiopharmaceuticals. Continuous improvement of scintillation detectors for radiation…

One of the features of the triplet state of positronium (ortho-Positronium)atoms is its relatively longer lifetime when compared to the singlet states ofpositronium (para-Positronium) atoms. The most probable decay of ortho-Positronium is…

Instrumentation and Detectors · Physics 2020-02-19 Juhi Raj , Kamil Dilski , Eryk Czerwinski

In this study, a fully self-consistent method was developed to obtain the wave functions of the positron and electrons in molecules simultaneously. The wave function of a positron at room temperature , with a characteristic energy of…

Atomic and Molecular Clusters · Physics 2020-06-24 Lin Tang , Xiaoguang Ma , Jipeng Sui , Meishan Wang , Chuanlu Yang

Positron scattering and annihilation on noble gas atoms below the positronium formation threshold is studied ab initio using many-body theory methods. The many-body theory provides a near-complete understanding of the…

Atomic Physics · Physics 2014-09-12 D. G. Green , J. A. Ludlow , G. F. Gribakin

Multiplex immunofluorescence (mIF) imaging technology facilitates the study of the tumour microenvironment in cancer patients. Due to the capabilities of this emerging bioimaging technique, it is possible to statistically analyse, for…

Applications · Statistics 2023-07-07 Jonatan A. González , Julia Wrobel , Simon Vandekar , Paula Moraga

The e$^+$ e$^-$ annihilation line at 511 keV provides a unique probe for studying the distribution and origin of positrons in our Galaxy. The SPI spectrometer on INTEGRAL has observed this gamma-ray line for two decades. We analyze 20 years…

High Energy Astrophysical Phenomena · Physics 2025-10-29 Hiroki Yoneda , Thomas Siegert , Saurabh Mittal

The application of information theory in medical imaging, particularly in magnetic resonance imaging (MRI), offers powerful quantitative tools for analyzing structural differences in brain tissues. This study utilizes mutual information…

Medical Physics · Physics 2025-05-13 Mazaher Kabiri , Shahd Qasem Mahd Tarman

Malignant brain tumors are among the deadliest neoplasms with the lowest survival rates of any cancer type. In considering surgical tumor resection, suboptimal extent of resection is linked to poor clinical outcomes and lower overall…

Image and Video Processing · Electrical Eng. & Systems 2020-09-23 Benjamin R. Ecclestone , Kevan Bell , Saad Abbasi , Deepak Dinakaran , Frank K. H. van Landeghem , John R. Mackey , Paul Fieguth , Parsin Haji Reza

We describe a novel method to use a scintillating fiber detector similar to the Fast Annihilation Cryogenic Tracking (FACT) used at the antimatter experiment AEgIS to monitor the presence of ortho-positronium. A single scintillating fiber…

Breast cancer is the most common type of cancer among women worldwide. The standard histopathology of breast tissue, the primary means of disease diagnosis, involves manual microscopic examination of stained tissue by a pathologist. Because…

Quantitative Methods · Quantitative Biology 2017-11-07 Hassaan Majeed , Tan Huu Nguyen , Mikhail Eugene Kandel , Andre Kajdacsy-Balla , Gabriel Popescu

The electron-positron annihilation spectrum observed by SPI/INTEGRAL during deep Galactic Center region exposure is reported. The line energy (510.954$\pm$0.075 keV) is consistent with the unshifted annihilation line. The width of the…

Astrophysics · Physics 2009-11-10 E. Churazov , R. Sunyaev , S. Sazonov , M. Revnivtsev , D. Varshalovich

Breast cancer survival prediction in computational pathology presents a remarkable challenge due to tumor heterogeneity. For instance, different regions of the same tumor in the pathology image can show distinct morphological and molecular…

Image and Video Processing · Electrical Eng. & Systems 2025-03-25 Yang Luo , Shiru Wang , Jun Liu , Jiaxuan Xiao , Rundong Xue , Zeyu Zhang , Hao Zhang , Yu Lu , Yang Zhao , Yutong Xie

This manuscript introduces a novel method to assess tissue oxygen concentration via the quantum entanglement (QE) of photons originating from positronium which is produced within the patient's body during positron emission tomography. We…

Medical Physics · Physics 2026-05-05 Pawel Moskal

The differential sparing of normal tissues relative to tumor control observed at ultra-high dose rates, referred to as the FLASH effect, has recently gained considerable attention. The therapeutic advantages of FLASH radiotherapy are…

The present paper proposes a novel model for estimating the free-volume size of porous materials based on the analysis of various experimental ortho-positronium ($o$-Ps) lifetime data. The model is derived by combining the semi-classical…

We develop a positronium imaging method for the Jagiellonian PET (J-PET) scanners based on the time-of-flight maximum likelihood expectation maximisation (TOF MLEM). The system matrix elements are calculated on-the-fly for the coincidences…

Instrumentation and Detectors · Physics 2023-10-19 Roman Y. Shopa , Kamil Dulski