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Fast Multipole Methods (FMM) are a fundamental operation for the simulation of many physical problems. The high performance design of such methods usually requires to carefully tune the algorithm for both the targeted physics and the…

Distributed, Parallel, and Cluster Computing · Computer Science 2012-06-04 Emmanuel Agullo , Béranger Bramas , Olivier Coulaud , Eric Darve , Matthias Messner , Takahashi Toru

Purpose: The importance of robust proton treatment planning to mitigate the impact of uncertainty is well understood. However, its computational cost grows with the number of uncertainty scenarios, prolonging the treatment planning process.…

Medical Physics · Physics 2023-05-01 Anqi Fu , Vicki T. Taasti , Masoud Zarepisheh

Energy system optimization models are increasing in scope and resolution, yielding large and challenging linear programs. For a long time, the standard way to address such problems has relied on shared-memory interior-point methods (IPM),…

Optimization and Control · Mathematics 2026-05-07 Janina Zittel , Annika Buchholz , Michael Bussieck , Frederik Fiand , Thorsten Koch , Lukas Mehl , Niels Lindner , Manuel Wetzel

Byte-addressable persistent memory (B-APM) presents a new opportunity to bridge the performance gap between main memory and storage. In this paper, we present the usage scenarios for this new technology, based on the capabilities of Intel's…

Distributed, Parallel, and Cluster Computing · Computer Science 2020-12-14 Michele Weiland , Bernhard Homoelle

General-purpose Sparse Matrix-Matrix Multiplication (SpMM) is a fundamental kernel in scientific computing and deep learning. The emergence of new matrix computation units such as Tensor Cores (TCs) brings more opportunities for SpMM…

Distributed, Parallel, and Cluster Computing · Computer Science 2025-01-17 Haisha Zhao , San Li , Jiaheng Wang , Chunbao Zhou , Jue Wang , Zhikuang Xin , Shunde Li , Zhiqiang Liang , Zhijie Pan , Fang Liu , Yan Zeng , Yangang Wang , Xuebin Chi

Diffusion models (DMs) have been adopted across diverse fields with its remarkable abilities in capturing intricate data distributions. In this paper, we propose a Fast Diffusion Model (FDM) to significantly speed up DMs from a stochastic…

Computer Vision and Pattern Recognition · Computer Science 2023-10-05 Zike Wu , Pan Zhou , Kenji Kawaguchi , Hanwang Zhang

The validation, verification, and uncertainty quantification of computationally expensive theoretical models of quantum many-body systems require the construction of fast and accurate emulators. In this work, we develop emulators for…

Exascale systems are predicted to have approximately one billion cores, assuming Gigahertz cores. Limitations on affordable network topologies for distributed memory systems of such massive scale bring new challenges to the current parallel…

Distributed, Parallel, and Cluster Computing · Computer Science 2014-05-27 Huda Ibeid , Rio Yokota , David Keyes

Profile hidden Markov models (pHMMs) are widely employed in various bioinformatics applications to identify similarities between biological sequences, such as DNA or protein sequences. In pHMMs, sequences are represented as graph…

The proliferation of high-throughput sequencing machines ensures rapid generation of up to billions of short nucleotide fragments in a short period of time. This massive amount of sequence data can quickly overwhelm today's storage and…

Distributed, Parallel, and Cluster Computing · Computer Science 2018-11-13 Subho S. Banerjee , Mohamed El-Hadedy , Jong Bin Lim , Zbigniew T. Kalbarczyk , Deming Chen , Steve Lumetta , Ravishankar K. Iyer

Sparse Matrix-matrix Multiplication (SpMM) and Sampled Dense-dense Matrix Multiplication (SDDMM) are important sparse operators in scientific computing and deep learning. Tensor Core Units (TCUs) enhance modern accelerators with superior…

Distributed, Parallel, and Cluster Computing · Computer Science 2024-12-17 Jinliang Shi , Shigang Li , Youxuan Xu , Rongtian Fu , Xueying Wang , Tong Wu

Branching processes are a class of continuous-time Markov chains (CTMCs) prevalent for modeling stochastic population dynamics in ecology, biology, epidemiology, and many other fields. The transient or finite-time behavior of these systems…

Computation · Statistics 2023-02-24 Achal Awasthi , Jason Xu

Mixed-precision quantization is a promising approach for compressing large language models under tight memory budgets. However, existing mixed-precision methods typically suffer from one of two limitations: they either rely on expensive…

Machine Learning · Computer Science 2026-02-03 Xin Nie , Haicheng Zhang , Liang Dong , Beining Feng , Jinhong Weng , Guiling Sun

Large language models have high compute, latency, and memory requirements. While specialized accelerators such as GPUs and TPUs typically run these workloads, CPUs are more widely available and consume less energy. Accelerating LLMs with…

Arbitrary-precision integer multiplication is the core kernel of many applications in simulation, cryptography, etc. Existing acceleration of arbitrary-precision integer multiplication includes CPUs, GPUs, FPGAs, and ASICs. Among these…

Hardware Architecture · Computer Science 2023-09-22 Zhuoping Yang , Jinming Zhuang , Jiaqi Yin , Cunxi Yu , Alex K. Jones , Peipei Zhou

As programmers turn to software-defined hardware (SDH) to maintain a high level of productivity while programming hardware to run complex algorithms, heavy-lifting must be done by the compiler to automatically partition on-chip arrays. In…

Hardware Architecture · Computer Science 2022-03-31 Matthew Feldman , Tian Zhao , Kunle Olukotun

In this article, we present a novel approach for block-structured adaptive mesh refinement (AMR) that is suitable for extreme-scale parallelism. All data structures are designed such that the size of the meta data in each distributed…

Distributed, Parallel, and Cluster Computing · Computer Science 2018-07-24 Florian Schornbaum , Ulrich Rüde

The rapid adaptation of data driven AI models, such as deep learning inference, training, Vision Transformers (ViTs), and other HPC applications, drives a strong need for runtime precision configurable different non linear activation…

Hardware Architecture · Computer Science 2026-02-12 Mukul Lokhande , Gopal Raut , Santosh Kumar Vishvakarma

The increasing computational demands of modern AI systems have exposed fundamental limitations of digital hardware, driving interest in alternative paradigms for efficient large-scale inference. Dense Associative Memory (DenseAM) is a…

Neural and Evolutionary Computing · Computer Science 2025-12-18 Marc Gong Bacvanski , Xincheng You , John Hopfield , Dmitry Krotov

General Matrix Multiplication (GEMM) is a fundamental operation widely used in scientific computations. Its performance and accuracy significantly impact the performance and accuracy of applications that depend on it. One such application…

Distributed, Parallel, and Cluster Computing · Computer Science 2023-06-12 Fumiya Kono , Naohito Nakasato , Maho Nakata