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Diffusion Large Language Models (dLLMs) enable breakthroughs in reasoning and parallel decoding but suffer from prohibitive quadratic computational complexity and memory overhead during inference. Current caching techniques accelerate…

Computation and Language · Computer Science 2025-11-06 Yuerong Song , Xiaoran Liu , Ruixiao Li , Zhigeng Liu , Zengfeng Huang , Qipeng Guo , Ziwei He , Xipeng Qiu

Ensemble methods are commonly used to enhance the generalization performance of machine learning models. However, they present a challenge in deep learning systems due to the high computational overhead required to train an ensemble of deep…

Machine Learning · Computer Science 2023-05-24 Hao Guo , Jiyong Jin , Bin Liu

Calculating relative free energies is a topic of substantial interest and has many applications including solvation and binding free energies, which are used in computational drug discovery. However, there remain the challenges of accuracy,…

Chemical Physics · Physics 2016-09-28 Asaf Farhi , Bipin Singh

The rapid adoption of low-precision arithmetic in artificial intelligence and edge computing has created a strong demand for energy-efficient and flexible floating-point multiply-accumulate (MAC) units. This paper presents a dual-precision…

Hardware Architecture · Computer Science 2026-04-10 Shubham Kumar , Vijay Pratap Sharma , Vaibhav Neema , Santosh Kumar Vishvakarma

We present a highly scalable, MPI-parallelized framework for reconstructing the initial cosmic density field, designed to meet the computational demands of next-generation cosmological simulations, particularly the upcoming ELUCID-DESI…

Edge computing must be capable of executing computationally intensive algorithms, such as Deep Neural Networks (DNNs) while operating within a constrained computational resource budget. Such computations involve Matrix Vector…

Hardware Architecture · Computer Science 2023-10-24 Arani Roy , Kaushik Roy

We present the open source distributed software package Poisson-Boltzmann Analytical Method (PB-AM), a fully analytical solution to the linearized Poisson Boltzmann equation, for molecules represented as non-overlapping spherical cavities.…

Biomolecules · Quantitative Biology 2016-09-27 Lisa E. Feldberg , David H. Brookes , Eng-Hui Yap , Elizabeth Jurrus , Nathan Baker , Teresa Head-Gordon

Restricted Boltzmann machines (RBMs) and their extensions, called 'deep-belief networks', are powerful neural networks that have found applications in the fields of machine learning and artificial intelligence. The standard way to training…

Machine Learning · Computer Science 2018-10-25 Haik Manukian , Fabio L. Traversa , Massimiliano Di Ventra

Deep-learning accelerators are increasingly in demand; however, their performance is constrained by the size of the feature map, leading to high bandwidth requirements and large buffer sizes. We propose an adaptive scale feature map…

Computer Vision and Pattern Recognition · Computer Science 2025-03-25 Yuan Yao , Tian-Sheuan Chang

DScribe is a software package for machine learning that provides popular feature transformations ("descriptors") for atomistic materials simulations. DScribe accelerates the application of machine learning for atomistic property prediction…

The present work attempts to integrate the independent efforts in the fast N-body community to create the fastest N-body library for many-core and heterogenous architectures. Focus is placed on low accuracy optimizations, in response to the…

Numerical Analysis · Computer Science 2012-09-20 Rio Yokota

Power consumption has become the major concern in neural network accelerators for edge devices. The novel non-volatile-memory (NVM) based computing-in-memory (CIM) architecture has shown great potential for better energy efficiency.…

Systems and Control · Electrical Eng. & Systems 2024-02-22 Haobo Liu , Zhengyang Qian , Wei Wu , Hongwei Ren , Zhiwei Liu , Leibin Ni

A key motivation in the development of Distributed Model Predictive Control (DMPC) is to accelerate centralized Model Predictive Control (MPC) for large-scale systems. DMPC has the prospect of scaling well by parallelizing computations…

Optimization and Control · Mathematics 2025-04-16 Gösta Stomberg , Maurice Raetsch , Alexander Engelmann , Timm Faulwasser

Combinatorial Optimization (CO) problems exhibit exponential complexity, making their resolution challenging. Simulated Adiabatic Bifurcation (aSB) is a quantum-inspired algorithm to obtain approximate solutions to largescale CO problems…

Systems and Control · Electrical Eng. & Systems 2025-10-16 Fabrizio Orlando , Deborah Volpe , Giacomo Orlandi , Mariagrazia Graziano , Fabrizio Riente , Marco Vacca

We adapted existing polymer growth strategies for equilibrium sampling of peptides described by modern atomistic forcefields with implicit solvent. The main novel feature of our approach is the use of pre-calculated statistical libraries of…

Biological Physics · Physics 2010-03-04 A. B. Mamonov , X. Zhang , D. M. Zuckerman

Scalable and efficient numerical simulations continue to gain importance, as computation is firmly established as the third pillar of discovery, alongside theory and experiment. Meanwhile, the performance of computing hardware grows through…

Distributed, Parallel, and Cluster Computing · Computer Science 2019-06-26 Pietro Incardona , Antonio Leo , Yaroslav Zaluzhnyi , Rajesh Ramaswamy , Ivo F. Sbalzarini

Tensor algebra is a crucial component for data-intensive workloads such as machine learning and scientific computing. As the complexity of data grows, scientists often encounter a dilemma between the highly specialized dense tensor algebra…

Programming Languages · Computer Science 2024-07-19 Mahdi Ghorbani , Emilien Bauer , Tobias Grosser , Amir Shaikhha

We present efficient algorithms to build data structures and the lists needed for fast multipole methods. The algorithms are capable of being efficiently implemented on both serial, data parallel GPU and on distributed architectures. With…

Mathematical Software · Computer Science 2013-01-10 Qi Hu , Nail A. Gumerov , Ramani Duraiswami

Optical computing has been recently proposed as a new compute paradigm to meet the demands of future AI/ML workloads in datacenters and supercomputers. However, proposed implementations so far suffer from lack of scalability, large…

Hardware Architecture · Computer Science 2022-10-21 Daniel Sturm , Sajjad Moazeni

Addressing the growing demands of artificial intelligence (AI) and data analytics requires new computing approaches. In this paper, we propose a reconfigurable hardware accelerator designed specifically for AI and data-intensive…

Hardware Architecture · Computer Science 2026-02-05 Md Rownak Hossain Chowdhury , Mostafizur Rahman
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