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Interference between pharmacological substances can cause serious medical injuries. Correctly predicting so-called drug-drug interactions (DDI) does not only reduce these cases but can also result in a reduction of drug development cost.…

Machine Learning · Computer Science 2019-08-06 Md. Rezaul Karim , Michael Cochez , Joao Bosco Jares , Mamtaz Uddin , Oya Beyan , Stefan Decker

During the growing popularity of electronic medical records, electronic medical record (EMR) data has exploded increasingly. It is very meaningful to retrieve high quality EMR in mass data. In this paper, an EMR value network with retrieval…

Computer Vision and Pattern Recognition · Computer Science 2019-11-22 Yongpei Zhu , Xuesheng Zhang , Kehong Yuan

Electronic Health Records (EHR) are high-dimensional data with implicit connections among thousands of medical concepts. These connections, for instance, the co-occurrence of diseases and lab-disease correlations can be informative when…

Machine Learning · Computer Science 2021-03-29 Weicheng Zhu , Narges Razavian

We introduce a framework for AI-based medical consultation system with knowledge graph embedding and reinforcement learning components and its implement. Our implement of this framework leverages knowledge organized as a graph to have…

Machine Learning · Computer Science 2021-08-31 Yining Huang , Meilian Chen , Keke Tang

Recommending safe and effective medication combinations from electronic health records (EHRs) is a core clinical AI problem, yet it remains difficult because patient trajectories are long, noisy, and clinically heterogeneous. Existing…

Machine Learning · Computer Science 2026-05-21 Krati Saxena , Tomohiro Shibata

Nowadays Knowledge Graphs constitute a mainstream approach for the representation of relational information on big heterogeneous data, however, they may contain a big amount of imputed noise when constructed automatically. To address this…

Machine Learning · Computer Science 2020-12-15 K. Bougiatiotis , R. Fasoulis , F. Aisopos , A. Nentidis , G. Paliouras

A large-scale knowledge graph enhances reproducibility in biomedical data discovery by providing a standardized, integrated framework that ensures consistent interpretation across diverse datasets. It improves generalizability by connecting…

Methodology · Statistics 2024-10-11 Suqi Liu , Tianxi Cai , Xiaoou Li

Item recommendation tasks are a widely studied topic. Recent developments in deep learning and spectral methods paved a path towards efficient graph embedding techniques. But little research has been done on applying these graph embedding…

Social and Information Networks · Computer Science 2019-08-27 Vishwas Sathish , Tanya Mehrotra , Simran Dhinwa , Bhaskarjyoti Das

Multi-behavior recommendation (MBR) aims to improve the performance w.r.t. the target behavior (i.e., purchase) by leveraging auxiliary behaviors (e.g., click, favourite). However, in real-world scenarios, a recommendation method often…

Information Retrieval · Computer Science 2026-01-13 Wenhao Lai , Weike Pan , Zhong Ming

Personalized recommendations are popular in these days of Internet driven activities, specifically shopping. Recommendation methods can be grouped into three major categories, content based filtering, collaborative filtering and machine…

Information Retrieval · Computer Science 2021-01-11 Yuhao Mao , Serguei A. Mokhov , Sudhir P. Mudur

Large language models (LLMs) are rapidly transforming various domains, including biomedicine and healthcare, and demonstrate remarkable potential from scientific research to new drug discovery. Graph-based retrieval-augmented generation…

Quantitative Methods · Quantitative Biology 2025-11-14 Guofeng Meng , Li Shen , Qiuyan Zhong , Wei Wang , Haizhou Zhang , Xiaozhen Wang

Data in Knowledge Graphs often represents part of the current state of the real world. Thus, to stay up-to-date the graph data needs to be updated frequently. To utilize information from Knowledge Graphs, many state-of-the-art machine…

Machine Learning · Computer Science 2021-09-23 Christopher Wewer , Florian Lemmerich , Michael Cochez

Rule mining on knowledge graphs allows for explainable link prediction. Contrarily, embedding-based methods for link prediction are well known for their generalization capabilities, but their predictions are not interpretable. Several…

Artificial Intelligence · Computer Science 2024-06-17 N'Dah Jean Kouagou , Arif Yilmaz , Michel Dumontier , Axel-Cyrille Ngonga Ngomo

Knowledge graphs capture structured information and relations between a set of entities or items. As such knowledge graphs represent an attractive source of information that could help improve recommender systems. However, existing…

Machine Learning · Computer Science 2019-06-17 Hongwei Wang , Fuzheng Zhang , Mengdi Zhang , Jure Leskovec , Miao Zhao , Wenjie Li , Zhongyuan Wang

Designing a new clinical trial entails many decisions, such as defining a cohort and setting the study objectives to name a few, and therefore can benefit from recommendations based on exhaustive mining of past clinical trial records. Here,…

Artificial Intelligence · Computer Science 2023-09-29 Murthy V. Devarakonda , Smita Mohanty , Raja Rao Sunkishala , Nag Mallampalli , Xiong Liu

Multimodal electronic health record (EHR) data is useful for disease risk prediction based on medical domain knowledge. However, general medical knowledge must be adapted to specific healthcare settings and patient populations to achieve…

Artificial Intelligence · Computer Science 2025-09-29 Mbithe Nzomo , Deshendran Moodley

Multiple sclerosis (MS) is a chronic autoimmune disease that affects the central nervous system. The progression and severity of MS varies by individual, but it is generally a disabling disease. Although medications have been developed to…

Applications · Statistics 2013-03-06 Joyce C. Ho , Joydeep Ghosh , KP Unnikrishnan

Reasoning is essential for the development of large knowledge graphs, especially for completion, which aims to infer new triples based on existing ones. Both rules and embeddings can be used for knowledge graph reasoning and they have their…

Artificial Intelligence · Computer Science 2019-03-22 Wen Zhang , Bibek Paudel , Liang Wang , Jiaoyan Chen , Hai Zhu , Wei Zhang , Abraham Bernstein , Huajun Chen

As science advances, the academic community has published millions of research papers. Researchers devote time and effort to search relevant manuscripts when writing a paper or simply to keep up with current research. In this paper, we…

Information Retrieval · Computer Science 2018-12-11 Haofeng Jia , Erik Saule

MultiModal Recommendation (MMR) systems have emerged as a promising solution for improving recommendation quality by leveraging rich item-side modality information, prompting a surge of diverse methods. Despite these advances, existing…

Information Retrieval · Computer Science 2025-08-25 Xiaoxiong Zhang , Xin Zhou , Zhiwei Zeng , Yongjie Wang , Dusit Niyato , Zhiqi Shen