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Knowledge Graphs have been one of the fundamental methods for integrating heterogeneous data sources. Integrating heterogeneous data sources is crucial, especially in the biomedical domain, where central data-driven tasks such as drug…

Machine Learning · Computer Science 2020-12-22 Islam Akef Ebeid , Majdi Hassan , Tingyi Wanyan , Jack Roper , Abhik Seal , Ying Ding

Background: Identifying new indications for approved drugs is a complex and time-consuming process that requires extensive knowledge of pharmacology, clinical data, and advanced computational methods. Recently, deep learning (DL) methods…

Machine Learning · Computer Science 2025-11-13 Shuting Jin , Yi Jiang , Yimin Liu , Tengfei Ma , Dongsheng Cao , Leyi Wei , Xiangrong Liu , Xiangxiang Zeng

Question answering is a natural language understanding task that involves reasoning over both explicit context, and unstated relevant domain knowledge. Despite the high cost of training, large language models (LLMs) -- the backbone of most…

Computation and Language · Computer Science 2025-04-24 Laura Cabello , Carmen Martin-Turrero , Uchenna Akujuobi , Anders Søgaard , Carlos Bobed

The objective of this work is to develop an Electronic Medical Record (EMR) data processing tool that confers clinical context to Machine Learning (ML) algorithms for error handling, bias mitigation and interpretability. We present…

Knowledge Graph Completion has been increasingly adopted as a useful method for helping address several tasks in biomedical research, such as drug repurposing or drug-target identification. To that end, a variety of datasets and Knowledge…

Machine Learning · Computer Science 2025-11-07 Alberto Cattaneo , Stephen Bonner , Thomas Martynec , Edward Morrissey , Carlo Luschi , Ian P Barrett , Daniel Justus

Medical knowledge graphs (KGs) constructed from Electronic Medical Records (EMR) contain abundant information about patients and medical entities. The utilization of KG embedding models on these data has proven to be efficient for different…

Information Retrieval · Computer Science 2021-04-06 Aynur Guluzade , Endri Kacupaj , Maria Maleshkova

Electronic Medical Records (EMRs), while integral to modern healthcare, present challenges for clinical reasoning and diagnosis due to their complexity and information redundancy. To address this, we proposed medIKAL (Integrating Knowledge…

Computation and Language · Computer Science 2025-02-18 Mingyi Jia , Junwen Duan , Yan Song , Jianxin Wang

Knowledge graphs have proven to be effective for modeling entities and their relationships through the use of ontologies. The recent emergence in interest for using knowledge graphs as a form of information modeling has led to their…

Artificial Intelligence · Computer Science 2023-07-21 Ngoc Luyen Le , Marie-Hélène Abel , Philippe Gouspillou

Electronic medical record (EMR) data contains historical sequences of visits of patients, and each visit contains rich information, such as patient demographics, hospital utilisation and medical codes, including diagnosis, procedure and…

Machine Learning · Computer Science 2020-07-24 Bhagya Hettige , Yuan-Fang Li , Weiqing Wang , Suong Le , Wray Buntine

In clinical treatment, identifying potential adverse reactions of drugs can help assist doctors in making medication decisions. In response to the problems in previous studies that features are high-dimensional and sparse, independent…

Quantitative Methods · Quantitative Biology 2024-07-30 Yufeng Li , Wenchao Zhao , Bo Dang , Xu Yan , Weimin Wang , Min Gao , Mingxuan Xiao

Learning low-dimensional embeddings of knowledge graphs is a powerful approach used to predict unobserved or missing edges between entities. However, an open challenge in this area is developing techniques that can go beyond simple edge…

Social and Information Networks · Computer Science 2019-10-30 William L. Hamilton , Payal Bajaj , Marinka Zitnik , Dan Jurafsky , Jure Leskovec

Medical deep learning models depend heavily on domain-specific knowledge to perform well on knowledge-intensive clinical tasks. Prior work has primarily leveraged unimodal knowledge graphs, such as the Unified Medical Language System…

Artificial Intelligence · Computer Science 2025-05-26 Xiaochen Wang , Yuan Zhong , Lingwei Zhang , Lisong Dai , Ting Wang , Fenglong Ma

Embeddings of medical concepts such as medication, procedure and diagnosis codes in Electronic Medical Records (EMRs) are central to healthcare analytics. Previous work on medical concept embedding takes medical concepts and EMRs as words…

Computation and Language · Computer Science 2018-06-11 Xiangrui Cai , Jinyang Gao , Kee Yuan Ngiam , Beng Chin Ooi , Ying Zhang , Xiaojie Yuan

Recommender systems have become an essential component of many online platforms, providing personalized recommendations to users. A crucial aspect is embedding techniques that convert the high-dimensional discrete features, such as user and…

Information Retrieval · Computer Science 2025-10-23 Maolin Wang , Xinjian Zhao , Wanyu Wang , Sheng Zhang , Jiansheng Li , Bowen Yu , Binhao Wang , Shucheng Zhou , Dawei Yin , Qing Li , Ruocheng Guo , Xiangyu Zhao

The multimodal recommendation has gradually become the infrastructure of online media platforms, enabling them to provide personalized service to users through a joint modeling of user historical behaviors (e.g., purchases, clicks) and item…

Information Retrieval · Computer Science 2024-04-19 Zhiqiang Guo , Jianjun Li , Guohui Li , Chaoyang Wang , Si Shi , Bin Ruan

Risk adjustment has become an increasingly important tool in healthcare. It has been extensively applied to payment adjustment for health plans to reflect the expected cost of providing coverage for members. Risk adjustment models are…

Machine Learning · Computer Science 2019-07-16 Qiu-Yue Zhong , Andrew H. Fairless , Jasmine M. McCammon , Farbod Rahmanian

Schema matching is a critical task in data integration, particularly in the medical domain where disparate Electronic Health Record (EHR) systems must be aligned to standard models like OMOP CDM. While Large Language Models (LLMs) have…

Artificial Intelligence · Computer Science 2025-12-02 Mingyu Jeon , Jaeyoung Suh , Suwan Cho

Distributed representations of medical concepts have been used to support downstream clinical tasks recently. Electronic Health Records (EHR) capture different aspects of patients' hospital encounters and serve as a rich source for…

Computation and Language · Computer Science 2020-01-07 Shaika Chowdhury , Chenwei Zhang , Philip S. Yu , Yuan Luo

Knowledge Graph embedding provides a versatile technique for representing knowledge. These techniques can be used in a variety of applications such as completion of knowledge graph to predict missing information, recommender systems,…

Information Retrieval · Computer Science 2021-07-19 Shivani Choudhary , Tarun Luthra , Ashima Mittal , Rajat Singh

As an efficient model for knowledge organization, the knowledge graph has been widely adopted in several fields, e.g., biomedicine, sociology, and education. And there is a steady trend of learning embedding representations of knowledge…

Computation and Language · Computer Science 2024-04-01 Siyu Yao , Ruijie Wang , Shen Sun , Derui Bu , Jun Liu