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Representation learning on electronic health records (EHRs) plays a vital role in downstream medical prediction tasks. Although natural language processing techniques, such as recurrent neural networks, and self-attention, have been adapted…

Artificial Intelligence · Computer Science 2026-01-12 Xueping Peng , Guodong Long , Tao Shen , Sen Wang , Chengqi Zhang , Allison Clarke , Clement Schlegel

Drug repurposing has historically been an economically infeasible process for identifying novel uses for abandoned drugs. Modern machine learning has enabled the identification of complex biochemical intricacies in candidate drugs; however,…

Machine Learning · Computer Science 2025-09-16 Luke Delzer , Robert Kroleski , Ali K. AlShami , Jugal Kalita

Medication recommendation is a crucial task for intelligent healthcare systems. Previous studies mainly recommend medications with electronic health records (EHRs). However, some details of interactions between doctors and patients may be…

Computation and Language · Computer Science 2022-09-16 Zhenfeng He , Yuqiang Han , Zhenqiu Ouyang , Wei Gao , Hongxu Chen , Guandong Xu , Jian Wu

Biomedical Knowledge Graphs (BKGs) integrate diverse datasets to elucidate complex relationships within the biomedical field. Effective link prediction on these graphs can uncover valuable connections, such as potential novel drug-disease…

Computation and Language · Computer Science 2025-07-01 Tien Dang , Viet Thanh Duy Nguyen , Minh Tuan Le , Truong-Son Hy

Graph embeddings have become a key and widely used technique within the field of graph mining, proving to be successful across a broad range of domains including social, citation, transportation and biological. Graph embedding techniques…

Machine Learning · Computer Science 2018-06-21 Stephen Bonner , Ibad Kureshi , John Brennan , Georgios Theodoropoulos , Andrew Stephen McGough , Boguslaw Obara

Recently there has been a surge of interest in designing graph embedding methods. Few, if any, can scale to a large-sized graph with millions of nodes due to both computational complexity and memory requirements. In this paper, we relax…

Artificial Intelligence · Computer Science 2020-08-17 Jiongqian Liang , Saket Gurukar , Srinivasan Parthasarathy

As large language models (LLMs) continue to grow in size, their abilities to tackle complex tasks have significantly improved. However, issues such as hallucination and the lack of up-to-date knowledge largely remain unresolved. Knowledge…

Artificial Intelligence · Computer Science 2026-03-17 Lihui Liu

An embedding is a mapping from a set of nodes of a network into a real vector space. Embeddings can have various aims like capturing the underlying graph topology and structure, node-to-node relationship, or other relevant information about…

Machine Learning · Computer Science 2023-06-21 Ashkan Dehghan , Kinga Siuta , Agata Skorupka , Andrei Betlen , David Miller , Bogumil Kaminski , Pawel Pralat

Graph embedding provides an efficient solution for graph analysis by converting the graph into a low-dimensional space which preserves the structure information. In contrast to the graph structure data, the i.i.d. node embedding can be…

Machine Learning · Computer Science 2017-05-16 Hongyun Cai , Vincent W. Zheng , Kevin Chen-Chuan Chang

In recent years, we have witnessed the proliferation of knowledge graphs (KG) in various domains, aiming to support applications like question answering, recommendations, etc. A frequent task when integrating knowledge from different KGs is…

Databases · Computer Science 2023-06-08 Nikolaos Fanourakis , Vasilis Efthymiou , Dimitris Kotzinos , Vassilis Christophides

In electronic health record (EHR) mining, learning high-quality representations of medical concepts (e.g., standardized diagnosis, medication, and procedure codes) is fundamental for downstream clinical prediction. However, ro bust concept…

Machine Learning · Computer Science 2026-05-05 Mohsen Nayebi Kerdabadi , Arya Hadizadeh Moghaddam , Chen Chen , Dongjie Wang , Zijun Yao

With the explosive growth of Internet data, users are facing the problem of information overload, which makes it a challenge to efficiently obtain the required resources. Recommendation systems have emerged in this context. By filtering…

Information Retrieval · Computer Science 2024-10-22 Wenyi Liu , Rui Wang , Yuanshuai Luo , Jianjun Wei , Zihao Zhao , Junming Huang

Drug combination therapy is a well-established strategy for disease treatment with better effectiveness and less safety degradation. However, identifying novel drug combinations through wet-lab experiments is resource intensive due to the…

Machine Learning · Computer Science 2023-01-18 Zhihang Hu , Qinze Yu , Yucheng Guo , Taifeng Wang , Irwin King , Xin Gao , Le Song , Yu Li

Medication recommendation systems have gained significant attention in healthcare as a means of providing tailored and effective drug combinations based on patients' clinical information. However, existing approaches often suffer from…

Machine Learning · Computer Science 2024-08-13 Zihao Zhao , Yi Jing , Fuli Feng , Jiancan Wu , Chongming Gao , Xiangnan He

The integration of multimodal Electronic Health Records (EHR) data has significantly improved clinical predictive capabilities. Leveraging clinical notes and multivariate time-series EHR, existing models often lack the medical context…

Artificial Intelligence · Computer Science 2024-02-13 Yinghao Zhu , Changyu Ren , Shiyun Xie , Shukai Liu , Hangyuan Ji , Zixiang Wang , Tao Sun , Long He , Zhoujun Li , Xi Zhu , Chengwei Pan

Network embedding maps the nodes of a given network into a low-dimensional space such that the semantic similarities among the nodes can be effectively inferred. Most existing approaches use inner-product of node embedding to measure the…

Social and Information Networks · Computer Science 2021-01-21 Luodi Xie , Hong Shen , Jiaxin Ren

Knowledge graphs (KGs) have been increasingly employed for link prediction and recommendation using real-world datasets. However, the majority of current methods rely on static data, neglecting the dynamic nature and the hidden…

Artificial Intelligence · Computer Science 2024-02-20 Ruiyi Yang , Flora D. Salim , Hao Xue

Motivation: Biomedical knowledge graphs (KGs) are crucial for drug discovery and disease understanding, yet their completion and reasoning are challenging. Knowledge Embedding (KE) methods capture global semantics but struggle with dynamic…

Artificial Intelligence · Computer Science 2025-07-23 Yitong Lin , Jiaying He , Jiahe Chen , Xinnan Zhu , Jianwei Zheng , Tao Bo

Deep learning models have shown tremendous potential in learning representations, which are able to capture some key properties of the data. This makes them great candidates for transfer learning: Exploiting commonalities between different…

Knowledge graphs (KGs) have become vitally important in modern recommender systems, effectively improving performance and interpretability. Fundamentally, recommender systems aim to identify user interests based on historical interactions…

Information Retrieval · Computer Science 2024-03-20 Zezhong Xu , Yincen Qu , Wen Zhang , Lei Liang , Huajun Chen
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