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Resting state fMRI (rsfMRI) has been shown to be a promising tool to study intrinsic functional connectivity and assess its integrity in cerebral development. In neonates, where fMRI is limited to few paradigms, rsfMRI was shown to be a…

Image and Video Processing · Electrical Eng. & Systems 2022-04-12 V. Enguix , J. Kenley , D. Luck , J. Cohen-Adad , G. A. Lodygensky

In neuroimaging, extensive post-processing of resting-state functional MRI (rfMRI) data is necessary for its application and investigation in relation to brain-behavior associations. Such post-processing is used to derive brain…

Computational Geometry · Computer Science 2025-09-11 Ty Easley , Kevin Freese , Elizabeth Munch , Janine Bijsterbosch

Functional Magnetic Resonance Imaging (fMRI) is an imaging technique widely used to study human brain activity. fMRI signals in areas across the brain transiently synchronise and desynchronise their activity in a highly structured manner,…

Machine Learning · Computer Science 2025-08-12 Yiran Huang , Amirhossein Nouranizadeh , Christine Ahrends , Mengjia Xu

Motivated by cutting-edge applications like cryo-electron microscopy (cryo-EM), the Multi-Reference Alignment (MRA) model entails the learning of an unknown signal from repeated measurements of its images under the latent action of a group…

Statistics Theory · Mathematics 2022-03-11 Subhro Ghosh , Philippe Rigollet

Understanding the structure of the brain, and how it changes with time and disease, is a core goal of structural neuroimaging. Contemporary approaches to structural brain analysis are dominated by voxel-wise, mass-univariate methods such as…

Algebraic Topology · Mathematics 2026-04-28 Donato Quiccione , Mariam Pirashvili , Nathan Broomhead , Sean J. Fallon

Investigating temporal variability of functional connectivity is an emerging field in connectomics. Entering dynamic functional connectivity by applying sliding window techniques on resting-state fMRI (rs-fMRI) time courses emerged from…

Neurons and Cognition · Quantitative Biology 2015-11-04 Markus Goldhacker , Ana Maria Tomé , Mark W. Greenlee , Elmar W. Lang

Data-driven brain parcellations aim to provide a more accurate representation of an individual's functional connectivity, since they are able to capture individual variability that arises due to development or disease. This renders…

Neurons and Cognition · Quantitative Biology 2017-03-30 Sofia Ira Ktena , Salim Arslan , Sarah Parisot , Daniel Rueckert

Electroencephalogram (EEG) data is crucial for diagnosing mental health conditions but is costly and time-consuming to collect at scale. Synthetic data generation offers a promising solution to augment datasets for machine learning…

Signal Processing · Electrical Eng. & Systems 2025-07-08 Gideon Vos , Maryam Ebrahimpour , Liza van Eijk , Zoltan Sarnyai , Mostafa Rahimi Azghadi

Functional magnetic resonance imaging (fMRI) is an indispensable tool in modern neuroscience, providing a non-invasive window into whole-brain dynamics at millimeter-scale spatial resolution. However, fMRI is constrained by issues such as…

Image and Video Processing · Electrical Eng. & Systems 2025-09-09 Yamin Li , Ange Lou , Ziyuan Xu , Shengchao Zhang , Shiyu Wang , Dario J. Englot , Soheil Kolouri , Daniel Moyer , Roza G. Bayrak , Catie Chang

Connectivity studies using resting-state functional magnetic resonance imaging are increasingly pooling data acquired at multiple sites. While this may allow investigators to speed up recruitment or increase sample size, multisite studies…

Quantitative Methods · Quantitative Biology 2017-02-10 Christian Dansereau , Yassine Benhajali , Celine Risterucci , Emilio Merlo Pich , Pierre Orban , Douglas Arnold , Pierre Bellec

Functional magnetic resonance (fMRI) is an invaluable tool in studying cognitive processes in vivo. Many recent studies use functional connectivity (FC), partial correlation connectivity (PC), or fMRI-derived brain networks to predict…

Neurons and Cognition · Quantitative Biology 2023-08-04 Anton Orlichenko , Gang Qu , Kuan-Jui Su , Anqi Liu , Hui Shen , Hong-Wen Deng , Yu-Ping Wang

We analyze functional magnetic resonance imaging (fMRI) data from the Human Connectome Project (HCP) to match brain activities during a range of cognitive tasks. Our findings demonstrate that even basic linear machine learning models can…

Neurons and Cognition · Quantitative Biology 2025-10-08 Valeriya Kirova , Dzerassa Kadieva , Daniil Vlasenko , Isak B. Blank , Fedor Ratnikov

Machine learning (ML) has the potential to become an essential tool in supporting clinical decision-making processes, offering enhanced diagnostic capabilities and personalized treatment plans. However, outsourcing medical records to train…

We use methods from computational algebraic topology to study functional brain networks, in which nodes represent brain regions and weighted edges encode the similarity of fMRI time series from each region. With these tools, which allow one…

Quantitative Methods · Quantitative Biology 2020-08-27 Bernadette J. Stolz , Tegan Emerson , Satu Nahkuri , Mason A. Porter , Heather A. Harrington

Magnetic resonance imaging (MRI) has played a crucial role in fetal neurodevelopmental research. Structural annotations of MR images are an important step for quantitative analysis of the developing human brain, with Deep Learning providing…

Availability of large and diverse medical datasets is often challenged by privacy and data sharing restrictions. For successful application of machine learning techniques for disease diagnosis, prognosis, and precision medicine, large…

fMRI is a non-invasive technique for investigating brain activity, offering high-resolution insights into neural processes. Understanding and decoding cognitive brain states from fMRI depends on how functional interactions are represented.…

Neurons and Cognition · Quantitative Biology 2026-02-23 Daniil Vlasenko , Vadim Ushakov , Alexey Zaikin , Denis Zakharov

Diffusion-weighted magnetic resonance imaging (dMRI) allows non-invasive investigation of whole-brain connectivity, which can potentially help to reveal the brain's global network architecture and abnormalities involved in neurological and…

The estimation of sparse hierarchical components reflecting patterns of the brain's functional connectivity from rsfMRI data can contribute to our understanding of the brain's functional organization, and can lead to biomarkers of diseases.…

Machine Learning · Computer Science 2021-04-22 Dushyant Sahoo , Christos Davatzikos

In clinical practice, a segmentation network is often required to continually learn on a sequential data stream from multiple sites rather than a consolidated set, due to the storage cost and privacy restriction. However, during the…

Image and Video Processing · Electrical Eng. & Systems 2022-06-28 Jingyang Zhang , Peng Xue , Ran Gu , Yuning Gu , Mianxin Liu , Yongsheng Pan , Zhiming Cui , Jiawei Huang , Lei Ma , Dinggang Shen
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