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We propose a Bayesian framework for uncertainty quantification and comparison in brain connectivity graph analysis. Standard graph-based approaches typically rely on point estimates of correlation matrices, overlooking the uncertainty…

Methodology · Statistics 2026-05-29 Alice Chevaux , Julyan Arbel , Guillaume Kon Kam King , Sophie Achard

Recent studies on analyzing dynamic brain connectivity rely on sliding-window analysis or time-varying coefficient models which are unable to capture both smooth and abrupt changes simultaneously. Emerging evidence suggests state-related…

Applications · Statistics 2019-07-04 Chee-Ming Ting , Hernando Ombao , S. Balqis Samdin , Sh-Hussain Salleh

The extent to which different neural or artificial neural networks (models) rely on equivalent representations to support similar tasks remains a central question in neuroscience and machine learning. Prior work has typically compared…

Neurons and Cognition · Quantitative Biology 2026-04-06 Jialin Wu , Shreya Saha , Yiqing Bo , Meenakshi Khosla

This study investigated the dynamic connectivity patterns between EEG and fMRI modalities, contributing to our understanding of brain network interactions. By employing a comprehensive approach that integrated static and dynamic analyses of…

Machine Learning · Computer Science 2024-12-02 Guiran Liu , Binrong Zhu

Brain connectivity can be estimated through a wide number of analyses applied to electroencephalographic (EEG) data. However, substantial heterogeneity in the implementation of connectivity methods exist. Heterogeneity in conceptualization…

Neurons and Cognition · Quantitative Biology 2021-09-01 Aleksandra Miljevic , Neil W. Bailey , Fidel Vila-Rodriguez , Sally E. Herring , Paul B. Fitzgerald

Current non-invasive neuroimaging techniques trade off between spatial resolution and temporal resolution. While magnetoencephalography (MEG) can capture rapid neural dynamics and functional magnetic resonance imaging (fMRI) can spatially…

Neurons and Cognition · Quantitative Biology 2025-10-13 Beige Jerry Jin , Leila Wehbe

In many human brain network studies, we do not have sufficient number (n) of images relative to the number (p) of voxels due to the prohibitively expensive cost of scanning enough subjects. Thus, brain network models usually suffer the…

Artificial Intelligence · Computer Science 2016-06-30 Moo K. Chung , Victoria Vilalta-Gil , Paul J. Rathouz , Benjamin B. Lahey , David H. Zald

Electroencephalogram (EEG) microstate analysis entails finding dynamics of quasi-stable and generally recurrent discrete states in multichannel EEG time series data and relating properties of the estimated state-transition dynamics to…

Neurons and Cognition · Quantitative Biology 2024-03-07 Saiful Islam , Pitambar Khanra , Johan Nakuci , Sarah F. Muldoon , Takamitsu Watanabe , Naoki Masuda

Power system frequency could be captured by digital recordings and extracted to compare with a reference database for forensic time-stamp verification. It is known as the electric network frequency (ENF) criterion, enabled by the properties…

Cryptography and Security · Computer Science 2020-11-03 Guang Hua , Qingyi Wang , Dengpan Ye , Haijian Zhang

Cognition is increasingly framed in terms of information processing, yet most fMRI analyses focus on activation or functional connectivity rather than quantifying how information is stored and transferred. To remedy this problem, we propose…

Neurons and Cognition · Quantitative Biology 2026-02-04 Chetan Gohil , Oliver M. Cliff , James M. Shine , Ben D. Fulcher , Joseph T. Lizier

In neuroscience, functional brain connectivity describes the connectivity between brain regions that share functional properties. Neuroscientists often characterize it by a time series of covariance matrices between functional measurements…

Methodology · Statistics 2019-07-09 Zhenhua Lin , Dehan Kong , Qiang Sun

The human brain is a complex network comprised of functionally and anatomically interconnected brain regions. A growing number of studies have suggested that empirical estimates of brain networks may be useful for discovery of biomarkers of…

Neurons and Cognition · Quantitative Biology 2022-11-15 Andrew Hannum , Mario A. Lopez , Saúl A. Blanco , Richard F. Betzel

We propose a matrix factorization technique that decomposes the resting state fMRI (rs-fMRI) correlation matrices for a patient population into a sparse set of representative subnetworks, as modeled by rank one outer products. The…

Signal Processing · Electrical Eng. & Systems 2018-07-26 Niharika Shimona D'Souza , Mary Beth Nebel , Nicholas Wymbs , Stewart Mostofsky , Archana Venkataraman

Objective: Tinnitus affects 10-15% of the population yet lacks objective diagnostic biomarkers. This study applied machine learning to EEG and fMRI data to identify neural signatures distinguishing tinnitus patients from healthy controls.…

Signal Processing · Electrical Eng. & Systems 2025-10-28 Kiana Kiashemshaki , Sina Samieirad , Sarvenaz Erfani , Aryan Jalaeianbanayan , Nasibeh Asadi Isakan , Hossein Najafzadeh

Objective: SNP heritability estimates vary substantially across estimation strategies, yet the downstream consequences for polygenic risk score (PRS) construction remain poorly characterised. We systematically benchmarked heritability…

Genomics · Quantitative Biology 2026-04-06 Muhammad Muneeb , David B. Ascher

One of the central objectives of contemporary neuroimaging research is to create predictive models that can disentangle the connection between patterns of functional connectivity across the entire brain and various behavioral traits.…

Topological data analysis (TDA) has become a powerful approach over the last twenty years, mainly due to its ability to capture the shape and the geometry inherent in the data. Persistence homology, which is a particular tool in TDA, has…

Neurons and Cognition · Quantitative Biology 2024-01-12 Anass B. El-Yaagoubi , Shuhao Jiao , Moo K. Chung , Hernando Ombao

Purpose: Functional Magnetic Resonance Imaging (fMRI) data acquired through resting-state studies have been used to obtain information about the spontaneous activations inside the brain. One of the approaches for analysis and interpretation…

Image and Video Processing · Electrical Eng. & Systems 2022-02-24 Harshit Parmar , Brian Nutter , Rodney Long , Sameer Antani , Sunanda Mitra

Network science has been extensively developed to characterize structural properties of complex systems, including brain networks inferred from neuroimaging data. As a result of the inference process, networks estimated from experimentally…

Neurons and Cognition · Quantitative Biology 2017-03-10 Catalina Obando , Fabrizio De Vico Fallani

Alterations in brain connectivity have been associated with a variety of clinical disorders using functional magnetic resonance imaging (fMRI). We investigated empirically how the number of brain parcels (or scale) impacted the results of a…

Quantitative Methods · Quantitative Biology 2015-01-28 P. Bellec , Y. Benhajali , F. Carbonell , C. Dansereau , G. Albouy , M. Pelland , C. Craddock , O. Collignon , J. Doyon , E. Stip , P. Orban