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Recently, Big Data applications have rapidly expanded into different industries. Healthcare is also one the industries willing to use big data platforms so that some big data analytics tools have been adopted in this field to some extent.…

Distributed, Parallel, and Cluster Computing · Computer Science 2016-03-24 Saman Sarraf , Mehdi Ostadhashem

Causal relations among neuronal populations of the brain are studied through the so-called effective connectivity (EC) network. The latter is estimated from EEG or fMRI measurements, by inverting a generative model of the corresponding…

Systems and Control · Computer Science 2018-02-16 Giulia Prando , Mattia Zorzi , Alessandra Bertoldo , Alessandro Chiuso

In recent years there has been growing interest in measuring time-varying functional connectivity between different brain regions using resting-state functional magnetic resonance imaging (rs-fMRI) data. One way to assess the relationship…

Signal Processing · Electrical Eng. & Systems 2020-09-23 Hamed Honari , Ann S. Choe , Martin A. Lindquist

This paper describes an approach of using dynamic Structural Equation Modeling (SEM) analysis to estimate the connectivity networks from resting-state fMRI data measured by a multiband EPI sequence. Two structural equation models were…

Neurons and Cognition · Quantitative Biology 2017-04-03 Jiancheng Zhuang

In modern neuroscience, functional magnetic resonance imaging (fMRI) has been a crucial and irreplaceable tool that provides a non-invasive window into the dynamics of whole-brain activity. Nevertheless, fMRI is limited by hemodynamic…

Signal Processing · Electrical Eng. & Systems 2024-01-26 Yamin Li , Ange Lou , Ziyuan Xu , Shiyu Wang , Catie Chang

We conduct an imaging genetics study to explore how effective brain connectivity in the default mode network (DMN) may be related to genetics within the context of Alzheimer's disease and mild cognitive impairment. We develop an analysis of…

Neurons and Cognition · Quantitative Biology 2020-06-03 Yunlong Nie , Eugene Opoku , Laila Yasmin , Yin Song , Jie Wang , Sidi Wu , Vanessa Scarapicchia , Jodie Gawryluk , Liangliang Wang , Jiguo Cao , Farouk S. Nathoo

Large-scale biobanks are being collected around the world in efforts to better understand human health and risk factors for disease. They often survey hundreds of thousands of individuals, combining questionnaires with clinical, genetic,…

Quantitative Methods · Quantitative Biology 2019-03-19 Qifan Yang , Gennady V. Roshchupkin , Wiro J. Niessen , Sarah E. Medland , Alyssa H. Zhu , Paul M. Thompson , Neda Jahanshad

Matrix factorization techniques, especially Nonnegative Matrix Factorization (NMF), have been widely used for dimensionality reduction and interpretable data representation. However, existing NMF-based methods are inherently single-scale…

Machine Learning · Computer Science 2026-02-27 Jichao Zhang , Ran Miao , Limin Li

We present Entropic Mutual-Information Geometry Large-Language Model Alignment (ENIGMA), a novel approach to Large-Language Model (LLM) training that jointly improves reasoning, alignment and robustness by treating an organisation's…

Machine Learning · Computer Science 2025-10-17 Gareth Seneque , Lap-Hang Ho , Nafise Erfanian Saeedi , Jeffrey Molendijk , Ariel Kuperman , Tim Elson

As machine learning continues to gain momentum in the neuroscience community, we witness the emergence of novel applications such as diagnostics, characterization, and treatment outcome prediction for psychiatric and neurological disorders,…

Computer Vision and Pattern Recognition · Computer Science 2018-04-27 Maxim Sharaev , Alexander Andreev , Alexey Artemov , Alexander Bernstein , Evgeny Burnaev , Ekaterina Kondratyeva , Svetlana Sushchinskaya , Renat Akzhigitov

Recent years have witnessed an emerging trend in neuromorphic computing that centers around the use of brain connectomics as a blueprint for artificial neural networks. Connectomics-based neuromorphic computing has primarily focused on…

Neurons and Cognition · Quantitative Biology 2025-01-28 Bach Nguyen , Tianlong Chen , Shu Yang , Bojian Hou , Li Shen , Duy Duong-Tran

Diffusion imaging is an important method in the field of neuroscience, as it is sensitive to changes within the tissue microstructure of the human brain. However, a major challenge when using MRI to derive quantitative measures is that the…

Computer Vision and Pattern Recognition · Computer Science 2018-08-07 Simon Koppers , Luke Bloy , Jeffrey I. Berman , Chantal M. W. Tax , J. Christopher Edgar , Dorit Merhof

Functional Magnetic Resonance Imaging (fMRI) relies on multi-step data processing pipelines to accurately determine brain activity; among them, the crucial step of spatial smoothing. These pipelines are commonly suboptimal, given the local…

Computer Vision and Pattern Recognition · Computer Science 2017-10-03 Albert Vilamala , Kristoffer Hougaard Madsen , Lars Kai Hansen

The use of EEG biometrics, for the purpose of automatic people recognition, has received increasing attention in the recent years. Most of current analysis rely on the extraction of features characterizing the activity of single brain…

Neurons and Cognition · Quantitative Biology 2014-09-10 Daria La Rocca , Patrizio Campisi , Balazs Vegso , Peter Cserti , Gyorgy Kozmann , Fabio Babiloni , Fabrizio De Vico Fallani

Background: As an important branch of machine learning pipelines in medical imaging, radiomics faces two major challenges namely reproducibility and accessibility. In this work, we introduce open-radiomics, a set of radiomics datasets along…

Quantitative Methods · Quantitative Biology 2025-03-04 Khashayar Namdar , Matthias W. Wagner , Birgit B. Ertl-Wagner , Farzad Khalvati

Multimodal neuroimaging modeling has becomes a widely used approach but confronts considerable challenges due to heterogeneity, which encompasses variability in data types, scales, and formats across modalities. This variability…

Neurons and Cognition · Quantitative Biology 2025-04-15 Gang Qu , Ziyu Zhou , Vince D. Calhoun , Aiying Zhang , Yu-Ping Wang

In this paper, we propose a reservoir computing-based and directed graph analysis pipeline. The goal of this pipeline is to define an efficient brain representation for connectivity in stroke data derived from magnetic resonance imaging.…

Machine Learning · Computer Science 2025-01-28 Wojciech Ciezobka , Joan Falco-Roget , Cemal Koba , Alessandro Crimi

Resting State Networks (RSNs) of the brain extracted from Resting State functional Magnetic Resonance Imaging (RS-fMRI) are used in the pre-surgical planning to guide the neurosurgeon. This is difficult, though, as expert knowledge is…

The human brain exhibits large-scale spontaneous fluctuations that account for most of its total energy metabolism. Independent of any overt function, this immense ongoing activity likely creates or maintains a potential functional brain…

Neurons and Cognition · Quantitative Biology 2021-02-23 Ze Wang

The resting-state brain networks (RSNs) reflects the functional connectivity patterns between brain modules, providing essential foundations for decoding intrinsic neural information within the brain. It serves as one of the primary tools…

Human-Computer Interaction · Computer Science 2025-01-22 Shiang Hu , Xiao Gong , Xiaolong Huang , Jie Ruan , Pedro Antonio Valdes-Sosa