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Recent advances in digital imaging, e.g., increased number of pixels captured, have meant that the volume of data to be processed and analyzed from these images has also increased. Deep learning algorithms are state-of-the-art for analyzing…

Image and Video Processing · Electrical Eng. & Systems 2022-04-20 Maged Abdalla Helmy Abdou , Paulo Ferreira , Eric Jul , Tuyen Trung Truong

Searching for similar images in archives of histology and histopathology images is a crucial task that may aid in patient matching for various purposes, ranging from triaging and diagnosis to prognosis and prediction. Whole slide images…

The field of computational pathology has recently seen rapid advances driven by the development of modern vision foundation models (FMs), typically trained on vast collections of pathology images. Recent studies demonstrate that increasing…

Computer Vision and Pattern Recognition · Computer Science 2025-04-08 Mikhail Karasikov , Joost van Doorn , Nicolas Känzig , Melis Erdal Cesur , Hugo Mark Horlings , Robert Berke , Fei Tang , Sebastian Otálora

The rapidly evolving field of digital oncopathology faces significant challenges, including the need to address diverse and complex clinical questions, often involving rare conditions, with limited availability of labeled data. These…

Image and Video Processing · Electrical Eng. & Systems 2024-09-05 Jonathan Zalach , Inbal Gazy , Assaf Avinoam , Ron Sinai , Eran Shmuel , Inbar Gilboa , Christine Swisher , Naim Matasci , Reva Basho , David B. Agus

Providing high-quality electron images and hyperspectral X-ray maps is a focus of many modern electron microscopy laboratories. Nevertheless, further image processing and annotations are often needed to prepare them for publications and…

Image and Video Processing · Electrical Eng. & Systems 2021-03-24 Noah Kraft , Anette von der Handt

This article presents MuMFiM, an open source application for multiscale modeling of fibrous materials on massively parallel computers. MuMFiM uses two scales to represent fibrous materials such as biological network materials (extracellular…

Distributed, Parallel, and Cluster Computing · Computer Science 2026-05-04 Jacob Merson , Catalin Picu , Mark S. Shephard

Traditional whole slide image (WSI) analysis methods typically rely on the multiple instance learning (MIL) paradigm, which extracts patch-level features at high magnification and aggregates them for slide-level prediction. However, such…

Computer Vision and Pattern Recognition · Computer Science 2026-05-26 Jiusong Ge , Yingkang Zhan , Wenjie Zhao , Di Zhang , Ke Wang , Jiashuai Liu , Chunze Yang , Chengzu Li , Jian Zhang , Yuxin Dong , Ni Zhang , Qidong Liu , Mireia Crispin-Ortuzar , Huazhu Fu , Chen Li , Zeyu Gao

Computational analysis of whole slide images (WSIs) has seen significant research progress in recent years, with applications ranging across important diagnostic and prognostic tasks such as survival or cancer subtype prediction. Many…

Computer Vision and Pattern Recognition · Computer Science 2024-11-28 Zak Buzzard , Konstantin Hemker , Nikola Simidjievski , Mateja Jamnik

When dealing with giga-pixel digital pathology in whole-slide imaging, a notable proportion of data records holds relevance during each analysis operation. For instance, when deploying an image analysis algorithm on whole-slide images…

Image and Video Processing · Electrical Eng. & Systems 2023-08-22 Haoju Leng , Ruining Deng , Shunxing Bao , Dazheng Fang , Bryan A. Millis , Yucheng Tang , Haichun Yang , Xiao Wang , Yifan Peng , Lipeng Wan , Yuankai Huo

The field of computational pathology presents many challenges for computer vision algorithms due to the sheer size of pathology images. Histopathology images are large and need to be split up into image tiles or patches so modern…

Computer Vision and Pattern Recognition · Computer Science 2021-08-25 Rob Jewsbury , Abhir Bhalerao , Nasir Rajpoot

Bio image analysis has recently become one keystone of biological research but biologists tend to get lost in a plethora of available software and the way to adjust available tools to their own image analysis problem. We present BIII,…

Whole slide images (WSIs) are massive digital pathology files illustrating intricate tissue structures. Selecting a small, representative subset of patches from each WSI is essential yet challenging. Therefore, following the "Divide &…

Computer Vision and Pattern Recognition · Computer Science 2023-11-17 Abubakr Shafique , Saghir Alfasly , Areej Alsaafin , Peyman Nejat , Jibran A. Khan , H. R. Tizhoosh

In pathology image analysis, obtaining and maintaining high-quality annotated samples is an extremely labor-intensive task. To overcome this challenge, mixing-based methods have emerged as effective alternatives to traditional preprocessing…

Computer Vision and Pattern Recognition · Computer Science 2023-07-25 Tianyi Zhang , Zhiling Yan , Chunhui Li , Nan Ying , Yanli Lei , Yunlu Feng , Yu Zhao , Guanglei Zhang

Processing of medical images such as MRI or CT presents unique challenges compared to RGB images typically used in computer vision. These include a lack of labels for large datasets, high computational costs, and metadata to describe the…

Image and Video Processing · Electrical Eng. & Systems 2021-08-06 Fernando Pérez-García , Rachel Sparks , Sébastien Ourselin

The growth of the amount of medical image data produced on a daily basis in modern hospitals forces the adaptation of traditional medical image analysis and indexing approaches towards scalable solutions. The number of images and their…

Distributed, Parallel, and Cluster Computing · Computer Science 2015-10-26 Dimitrios Markonis , Roger Schaer , Ivan Eggel , Henning Müller , Adrien Depeursinge

Histopathology whole slide images (WSIs) play a very important role in clinical studies and serve as the gold standard for many cancer diagnoses. However, generating automatic tools for processing WSIs is challenging due to their enormous…

Computer Vision and Pattern Recognition · Computer Science 2022-09-28 Jingwei Zhang , Xin Zhang , Ke Ma , Rajarsi Gupta , Joel Saltz , Maria Vakalopoulou , Dimitris Samaras

The density of mitotic figures within tumor tissue is known to be highly correlated with tumor proliferation and thus is an important marker in tumor grading. Recognition of mitotic figures by pathologists is known to be subject to a strong…

Foundation models have revolutionized the paradigm of digital pathology, as they leverage general-purpose features to emulate real-world pathological practices, enabling the quantitative analysis of critical histological patterns and the…

The search and retrieval of digital histopathology slides is an important task that has yet to be solved. In this case study, we investigate the clinical readiness of three state-of-the-art histopathology slide search engines, Yottixel,…

Pathology images are considered the ``gold standard" for cancer diagnosis and treatment, with gigapixel images providing extensive tissue and cellular information. Existing methods fail to simultaneously extract global structural and local…

Computer Vision and Pattern Recognition · Computer Science 2025-02-17 Haoming Luo , Xiaotian Yu , Shengxuming Zhang , Jiabin Xia , Yang Jian , Yuning Sun , Liang Xue , Mingli Song , Jing Zhang , Xiuming Zhang , Zunlei Feng
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