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Noninvasive optical imaging modalities can probe patient's tissue in 3D and over time generate gigabytes of clinically relevant data per sample. There is a need for AI models to analyze this data and assist clinical workflow. The lack of…

Machine learning is revolutionizing image-based diagnostics in pathology and radiology. ML models have shown promising results in research settings, but their lack of interoperability has been a major barrier for clinical integration and…

This work addresses how to efficiently classify challenging histopathology images, such as gigapixel whole-slide images for cancer diagnostics with image-level annotation. We use images with annotated tumor regions to identify a set of…

Image and Video Processing · Electrical Eng. & Systems 2024-09-24 Mohammad Iqbal Nouyed , Mary-Anne Hartley , Gianfranco Doretto , Donald A. Adjeroh

The digitization of biological specimens has revolutionized the field of morphology, creating large collections of 3D data, and microCT in particular. This revolution was initially supported by the development of open-source software tools,…

Other Quantitative Biology · Quantitative Biology 2026-01-22 A. Murat Maga , Jean-Christophe Fillion-Robin

Histopathologic Images (HI) are the gold standard for evaluation of some tumors. However, the analysis of such images is challenging even for experienced pathologists, resulting in problems of inter and intra observer. Besides that, the…

Computer Vision and Pattern Recognition · Computer Science 2019-04-18 Jonathan de Matos , Alceu de Souza Britto , Luiz E. S. Oliveira , Alessandro L. Koerich

Quality assurance is a critical but underexplored area in digital pathology, where even minor artifacts can have significant effects. Artifacts have been shown to negatively impact the performance of AI diagnostic models. In current…

Image and Video Processing · Electrical Eng. & Systems 2025-06-13 Meredith VandeHaar , M. Clinch , I. Yilmaz , M. A. Rahman , Y. Xiao , F. Dogany , H. M. Alazab , A. Nassar , Z. Akkus , B. Dangott

Objective: The exchange of health-related data is subject to regional laws and regulations, such as the General Data Protection Regulation (GDPR) in the EU or the Health Insurance Portability and Accountability Act (HIPAA) in the United…

Computers and Society · Computer Science 2024-01-24 Tom Bisson , Michael Franz , Isil Dogan O , Daniel Romberg , Christoph Jansen , Peter Hufnagl , Norman Zerbe

Endomicroscopy is an emerging imaging modality, that facilitates the acquisition of in vivo, in situ optical biopsies, assisting diagnostic and potentially therapeutic interventions. While there is a diverse and constantly expanding range…

Computer Vision and Pattern Recognition · Computer Science 2020-01-01 Antonios Perperidis , Kevin Dhaliwal , Stephen McLaughlin , Tom Vercauteren

Tomographic imaging has benefited from advances in X-ray sources, detectors and optics to enable novel observations in science, engineering and medicine. These advances have come with a dramatic increase of input data in the form of faster…

Distributed, Parallel, and Cluster Computing · Computer Science 2020-12-25 Stefano Marchesini , Anuradha Trivedi , Pablo Enfedaque , Talita Perciano , Dilworth Parkinson

Summary: PDBImages is an innovative, open-source Node.js package that harnesses the power of the popular macromolecule structure visualization software Mol*. Designed for use by the scientific community, PDBImages provides a means to…

Biomolecules · Quantitative Biology 2024-01-03 Adam Midlik , Sreenath Nair , Stephen Anyango , Mandar Deshpande , David Sehnal , Mihaly Varadi , Sameer Velankar

Large-scale image data such as digital whole-slide histology images pose a challenging task at annotation software solutions. Today, a number of good solutions with varying scopes exist. For cell annotation, however, we find that many do…

Computer Vision and Pattern Recognition · Computer Science 2018-10-03 Marc Aubreville , Christof Bertram , Robert Klopfleisch , Andreas Maier

Digital whole slides images contain an enormous amount of information providing a strong motivation for the development of automated image analysis tools. Particularly deep neural networks show high potential with respect to various tasks…

Computer Vision and Pattern Recognition · Computer Science 2023-12-07 Michael Gadermayr , Maximilian Tschuchnig

Whole slide imaging (WSI) has transformed digital pathology by enabling computational analysis of gigapixel histopathology images. Recent foundation model advances have accelerated progress in computational pathology, facilitating joint…

Computer Vision and Pattern Recognition · Computer Science 2026-03-20 Peihang Wu , Zehong Chen , Lijian Xu

QuPath is open-source software for bioimage analysis. As a desktop application that is flexible and easy to install, QuPath is used by labs worldwide to visualise and analyse large and complex images. However, relying only on images stored…

Quantitative Methods · Quantitative Biology 2026-03-18 Léo Leplat , Alan O'Callaghan , Peter Bankhead

Multi-modal medical image fusion (MMIF) is increasingly recognized as an essential technique for enhancing diagnostic precision and facilitating effective clinical decision-making within computer-aided diagnosis systems. MMIF combines data…

Image and Video Processing · Electrical Eng. & Systems 2025-05-22 Muhammad Zubair , Muzammil Hussai , Mousa Ahmad Al-Bashrawi , Malika Bendechache , Muhammad Owais

The computer-aided analysis of medical scans is a longstanding goal in the medical imaging field. Currently, deep learning has became a dominant methodology for supporting pathologists and radiologist. Deep learning algorithms have been…

Machine Learning · Computer Science 2017-12-06 Jakub M. Tomczak , Maximilian Ilse , Max Welling

Over the past decade, deep learning (DL) research in computer vision has been growing rapidly, with many advances in DL-based image analysis methods for biomedical problems. In this work, we introduce MMV_Im2Im, a new open-source python…

Image and Video Processing · Electrical Eng. & Systems 2023-03-20 Justin Sonneck , Jianxu Chen

Modern imaging instruments can produce terabytes to petabytes of data for a single experiment. The biggest barrier to processing big image datasets has been computational, where image analysis algorithms often lack the efficiency needed to…

Computer Vision and Pattern Recognition · Computer Science 2026-03-13 Nicholas Schaub , Andriy Kharchenko , Hamdah Abbasi , Sameeul Samee , Hythem Sidky , Nathan Hotaling

The increasing availability of large institutional and public histopathology image datasets is enabling the searching of these datasets for diagnosis, research, and education. Though these datasets typically have associated metadata such as…

Medical images play a crucial role in modern healthcare by providing vital information for diagnosis, treatment planning, and disease monitoring. Fields such as radiology and pathology rely heavily on accurate image interpretation, with…

Image and Video Processing · Electrical Eng. & Systems 2024-08-06 H. R. Tizhoosh