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Genome assembly from the high-throughput sequencing (HTS) reads is a fundamental yet challenging computational problem. An intrinsic challenge is the uncertainty caused by the widespread repetitive elements. Here we get around the…

Genomics · Quantitative Biology 2016-09-13 Anqi Wang , Zheng Li , Zhanyu Wang , Lei M. Li

Modern key-value stores rely heavily on Log-Structured Merge (LSM) trees for write optimization, but this design introduces significant read amplification. Auxiliary structures like Bloom filters help, but impose memory costs that scale…

Data Structures and Algorithms · Computer Science 2025-08-05 Nicholas Fidalgo , Puyuan Ye

Unrolled neural networks have recently achieved state-of-the-art accelerated MRI reconstruction. These networks unroll iterative optimization algorithms by alternating between physics-based consistency and neural-network based…

Image and Video Processing · Electrical Eng. & Systems 2022-07-19 Batu Ozturkler , Arda Sahiner , Tolga Ergen , Arjun D Desai , Christopher M Sandino , Shreyas Vasanawala , John M Pauly , Morteza Mardani , Mert Pilanci

With the widespread use of deep neural networks(DNNs) in intelligent systems, DNN accelerators with high performance and energy efficiency are greatly demanded. As one of the feasible processing-in-memory(PIM) architectures,…

Hardware Architecture · Computer Science 2023-12-22 Junpeng Wang , Mengke Ge , Bo Ding , Qi Xu , Song Chen , Yi Kang

Image classification is an essential task in computer vision, which aims to categorise a set of images into different groups based on some visual criteria. Existing methods, such as convolutional neural networks, have been successfully…

Neural and Evolutionary Computing · Computer Science 2019-10-01 Benjamin Patrick Evans , Harith Al-Sahaf , Bing Xue , Mengjie Zhang

An important goal in microbial computational genomics is to identify crucial events in the evolution of a gene that severely alter the duplication, loss and mobilization patterns of the gene within the genomes in which it disseminates. In…

Quantitative Methods · Quantitative Biology 2019-12-05 Roni Zoller , Meirav Zehavi , Michal Ziv-Ukelson

This paper deals with the development of a localization methodology for autonomous vehicles using only a $3\Dim$ LIDAR sensor. In the context of this paper, localizing a vehicle in a known 3D global map of the environment is essentially to…

Robotics · Computer Science 2023-02-15 Naga Venkat Adurthi

Modern Machine Learning (ML) training on large-scale datasets is a very time-consuming workload. It relies on the optimization algorithm Stochastic Gradient Descent (SGD) due to its effectiveness, simplicity, and generalization performance.…

Hardware Architecture · Computer Science 2024-09-30 Steve Rhyner , Haocong Luo , Juan Gómez-Luna , Mohammad Sadrosadati , Jiawei Jiang , Ataberk Olgun , Harshita Gupta , Ce Zhang , Onur Mutlu

Generative retrieval (GR) reformulates the Information Retrieval (IR) task as the generation of document identifiers (docIDs). Despite its promise, existing GR models exhibit poor generalization to newly added documents, often failing to…

Information Retrieval · Computer Science 2026-05-12 Zhen Zhang , Zihan Wang , Xinyu Ma , Shuaiqiang Wang , Dawei Yin , Xin Xin , Pengjie Ren , Maarten de Rijke , Zhaochun Ren

There is increasing demand for specialized hardware for training deep neural networks, both in edge/IoT environments and in high-performance computing systems. The design space of such hardware is very large due to the wide range of…

Distributed, Parallel, and Cluster Computing · Computer Science 2022-05-03 Yangjie Qi , Shuo Zhang , Tarek M. Taha

A technique named Feature Learning from Image Markers (FLIM) was recently proposed to estimate convolutional filters, with no backpropagation, from strokes drawn by a user on very few images (e.g., 1-3) per class, and demonstrated for…

Computer Vision and Pattern Recognition · Computer Science 2020-12-23 Barbara C. Benato , Italos E. de Souza , Felipe L. Galvão , Alexandre X. Falcão

DNA sequencing, especially of microbial genomes and metagenomes, has been at the core of recent research advances in large-scale comparative genomics. The data deluge has resulted in exponential growth in genomic datasets over the past…

Computing-in-memory (CIM) is an emerging computing paradigm, offering noteworthy potential for accelerating neural networks with high parallelism, low latency, and energy efficiency compared to conventional von Neumann architectures.…

Neural and Evolutionary Computing · Computer Science 2024-09-30 Kam Chi Loong , Shihao Han , Sishuo Liu , Ning Lin , Zhongrui Wang

This paper proposes an iterative algorithm for choosing gradient directions use to reconstruct white matter fibers in the brain. The present study is not focusing on data acquisition where scanning is performed. The Adaptive Gradient…

Biomolecules · Quantitative Biology 2021-10-05 Ashishi Puri , Sanjeev Kumar

In the current deep learning based recommendation system, the embedding method is generally employed to complete the conversion from the high-dimensional sparse feature vector to the low-dimensional dense feature vector. However, as the…

Information Retrieval · Computer Science 2021-08-10 Huimin Zhou , Qing Li , Yong Jiang , Rongwei Yang , Zhuyun Qi

In this paper, we study the Multi-Round Influence Maximization (MRIM) problem, where influence propagates in multiple rounds independently from possibly different seed sets, and the goal is to select seeds for each round to maximize the…

Social and Information Networks · Computer Science 2019-06-07 Lichao Sun , Weiran Huang , Philip S. Yu , Wei Chen

Motivation: Illumina DNA sequencing is now the predominant source of raw genomic data, and data volumes are growing rapidly. Bioinformatic analysis pipelines are having trouble keeping pace. A common bottleneck in such pipelines is the…

Genomics · Quantitative Biology 2014-09-09 Gregory G. Faust , Ira M. Hall

Motivation: Next generation methods of DNA sequencing produce relatively high rate of reading errors, which interfere with de novo genome assembly of newly sequenced organisms and particularly affect the quality of SNP detection important…

Genomics · Quantitative Biology 2019-07-31 Oleg Fokin , Anastasia Bakulina , Igor Seledtsov , Victor Solovyev

Graph mining applications, such as subgraph pattern matching and mining, are widely used in real-world domains such as bioinformatics, social network analysis, and computer vision. Such applications are considered a new class of…

Hardware Architecture · Computer Science 2023-06-21 Jiya Su , Peng Jiang , Rujia Wang

Accurate mapping of irrigation methods is crucial for sustainable agricultural practices and food systems. However, existing models that rely solely on spectral features from satellite imagery are ineffective due to the complexity of…

Computer Vision and Pattern Recognition · Computer Science 2025-06-06 Oishee Bintey Hoque , Nibir Chandra Mandal , Abhijin Adiga , Samarth Swarup , Sayjro Kossi Nouwakpo , Amanda Wilson , Madhav Marathe
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